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Show all synonyms
Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 (show TP53 ELISA Kits) and inhibits AP-1 (show FOSB ELISA Kits) pathway.
TTC5 and EP300 (show EP300 ELISA Kits) cooperate to prevent excessive accumulation of MYC (show MYC ELISA Kits) in AML (show RUNX1 ELISA Kits) cells and their sensitization to cell death.
TTC5 is a novel cofactor regulating GR function in a stress-dependent manner.
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
tetratricopeptide repeat domain 5
, tetratricopeptide repeat protein 5
, tetratricopeptide repeat protein 5-like
, TPR repeat protein 5
, stress-responsive activator of p300