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anti-Human C1QA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended C1QA Antibody (supplied by: Log in to see )

Antigen
Complement Component 1, Q Subcomponent, A Chain (C1QA) Antibodies
  • AI255395
  • C1q
  • C1QA
  • zgc:109903
Epitope
AA 198-227, C-Term
6
6
4
4
3
2
2
1
1
1
Reactivity
Human
51
8
5
Host
Rabbit
34
11
5
3
2
1
Clonality
Polyclonal
Conjugate
This C1QA antibody is un-conjugated
4
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
21
8
4
4
4
3
2
2
1
1
1
1
1
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Catalog No. ABIN391492
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089850504 ABIN1019924 IHC (p) Rabbit IgG C-Term Log in to see EPR2980Y
0.00089850504 ABIN1805228 FACS IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Top referenced anti-C1QA antibody for Immunohistochemistry (Paraffin-embedded Sections)

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Immunohistochemistry (IHC) 8 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
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General

Antigen Complement Component 1, Q Subcomponent, A Chain (C1QA) Antibodies
Epitope AA 198-227, C-Term
(6), (6), (4), (4), (3), (2), (2), (1), (1), (1)
Reactivity Human
(51), (8), (5)
Host Rabbit
(34), (11), (5), (3), (2), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This C1QA antibody is un-conjugated
(4), (2)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(38), (21), (8), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-C1QA Antibody

Target Details C1QA Application Details Handling References for anti-C1QA Antibody (ABIN391492) Images
Specificity This C1QA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205~235 amino acids from the C-terminal region of human C1QA.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This C1QA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 AA from the C-terminal region of human C1QA.
Clone RB18692
Isotype Ig

Target Details C1QA

Product Details anti-C1QA Antibody Application Details Handling References for anti-C1QA Antibody (ABIN391492) Images back to top
Antigen
Alternative Name C1QA (C1QA Antibody Abstract)
Background C1QA is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on hromosome 1.
Synonyms: Complement C1q subcomponent subunit A, C1QA
Molecular Weight 26017 DA
Gene ID 712
UniProt P02745
Research Area Cancer, Cell Structure
Pathways Complement System

Application Details

Product Details anti-C1QA Antibody Target Details C1QA Handling References for anti-C1QA Antibody (ABIN391492) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-C1QA Antibody Target Details C1QA Application Details References for anti-C1QA Antibody (ABIN391492) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-C1QA Antibody (ABIN391492)

Product Details anti-C1QA Antibody Target Details C1QA Application Details Handling Images back to top
Background publications

Sjöberg, Nyström, Hammarström, Blom: "Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly." in: Molecular immunology, Vol. 45, Issue 11, pp. 3213-21, 2008

Images

Product Details anti-C1QA Antibody Target Details C1QA Application Details Handling References for anti-C1QA Antibody (ABIN391492) back to top
Supplier Images
Western Blotting (WB) image for anti-C1QA antibody (Complement Component 1, Q Subcomponent, A Chain) (AA 198-227) (ABIN391492) Western blot analysis of C1QA antibody (C-term) (ABIN391492) in Jurkat cell line lysa...
Immunohistochemistry (IHC) image for anti-C1QA antibody (Complement Component 1, Q Subcomponent, A Chain) (AA 198-227) (ABIN391492) C1QA Antibody (C-term) (ABIN391492) IHC analysis in formalin fixed and paraffin embed...
Flow Cytometry (FACS) image for anti-C1QA antibody (Complement Component 1, Q Subcomponent, A Chain) (AA 198-227) (ABIN391492) C1QA Antibody (C-term) (ABIN391492) FC analysis of MCF-7 cells (bottom histogram) com...