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Browse our C1QB Proteins (C1QB)

Full name:
Complement Component 1, Q Subcomponent, B Chain Proteins (C1QB)
On are 6 Complement Component 1, Q Subcomponent, B Chain (C1QB) Proteins from 4 different suppliers available. Additionally we are shipping C1QB Antibodies (47) and C1QB Kits (4) and many more products for this protein. A total of 67 C1QB products are currently listed.
list all proteins Gene Name GeneID UniProt
C1QB 713 P02746
C1QB 29687 P31721
C1QB 12260 P14106

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Human Complement Component 1, Q Subcomponent, B Chain (C1QB) interaction partners

  1. no significant association found to either rs15940 (C1QA (show C1QA Proteins)) or rs172378 (C1QC (show C1QC Proteins)) when analysed in just Parkinson disease cases , just controls or combined

  2. Data indicate that Cna binds to C1q.

  3. Analysis of its interaction properties by surface plasmon resonance shows that rC1q retains the ability of serum C1q to associate with the C1s (show C1S Proteins)-C1r-C1r (show C1R Proteins)-C1s (show C1S Proteins) tetramer, to recognize physiological C1q ligands such as IgG and pentraxin 3 (show PTX3 Proteins)

  4. Single nucleotide polymorphisms in and around the C1q genes, C1qA (show C1QA Proteins), C1qB and C1qC (show C1QC Proteins), correlated with C1q serum levels and may be a risk for the development of rheumatoid arthritis.

  5. The susceptibility for schizophrenia was particularly associated with C1QB rs291982 GG genotype.

  6. a 2-gene signature consisting of PLEK2 (show PLEK2 Proteins) and C1QB led to the best result that correctly classified 93.3% melanoma patients and 90% healthy controls

  7. Data show that C1q, C4, C3, and C9 bind to thrombin receptor (show F2R Proteins)-activating peptide-activated platelets in lepirudin-anticoagulated platelet-rich plasma (PRP (show C4BPA Proteins)) and whole blood.

  8. Experiments with recombinant globular head domains of human C1q A, B, and C chains indicated that C1q interacts with PTX3 (show PITX3 Proteins) via its globular head region. Binding of C1q to immobilized PTX3 (show PITX3 Proteins) induced activation of the classical complement pathway.

  9. The structure refined to 1.9 A of resolution of C1q reveals the conformation of subunits A, B, and C and their compact, almost spherical heterotrimeric assembly held together mainly by non-polar interactions, with a Ca2 (show CA2 Proteins)+ ion bound at the top.

  10. results suggest that charged residues belonging to the apex (show APEX1 Proteins) of the gC1q heterotrimer (with participation of all three chains) as well as the side of the ghB are crucial for C1q binding to ligands, IgG1, C-reactive protein (show CRP Proteins), and pentraxin 3 (show PTX3 Proteins).

Mouse (Murine) Complement Component 1, Q Subcomponent, B Chain (C1QB) interaction partners

  1. The mRNA levels of H2-d1 in the prefrontal cortex, hippocampus, and hypothalamus and C1qb in the hippocampus of the DBA (show RPS19 Proteins)/2 J strain were significantly down-regulated as compared to those in the C57BL/6 J strain

C1QB Protein Profile

Protein Summary

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q

Alternative names and synonyms associated with C1QB

  • complement component 1, q subcomponent, B chain (C1QB)
  • complement component 1, q subcomponent, B chain (C1qb)
  • complement component 1, q subcomponent, beta polypeptide (C1qb)

Protein level used designations for C1QB

complement C1q subcomponent subunit B , complement component 1, q subcomponent, beta polypeptide , complement component C1q, B chain , complement subcomponent C1q chain B , complement C1qB

713 Homo sapiens
487381 Canis lupus familiaris
29687 Rattus norvegicus
100518846 Sus scrofa
617435 Bos taurus
12260 Mus musculus
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