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anti-Human C3 antibody for Enzyme Immunoassay

Recommended C3 Antibody (supplied by: Log in to see )

Antigen
Complement Component 3 (C3) Antibodies
  • AHUS5
  • AI255234
  • ARMD9
  • asp
  • ASP
  • c3
  • C3
  • C3-1
  • C3a
  • C3b
  • C3d
  • c3_D
  • CPAMD1
  • cpamd1
  • HSE-MSF
  • Plp
  • sb:cb26
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11
Epitope
C-Term
13
11
6
5
5
4
3
3
3
3
2
2
1
1
1
1
Reactivity
Human
242
65
55
18
13
5
5
5
3
2
1
Host
Mouse
140
102
86
24
13
7
Clonality
Monoclonal
Conjugate
This C3 antibody is un-conjugated
34
31
20
6
6
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
193
187
71
67
59
45
44
42
40
35
33
24
20
5
4
1
1
1
1
1
1
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Catalog No. ABIN1106781
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008854274 ABIN181105 EIA WB Mouse IgG1 Log in to see 01-10-21 2
0.0008854274 ABIN317012 EIA FACS IHC (fro) WB Mouse IgG2b Log in to see 013III-1-16 3
0.0008854274 ABIN1106782 EIA WB Mouse IgG1 C-Term Log in to see 755 1
0.0008854274 ABIN1106783 EIA WB Biotin Mouse IgG1 Log in to see 474 4
0.0008854274 ABIN112153 EIA IHC (fro) WB Mouse IgG1 Log in to see H206 1
0.0008854274 ABIN1106778 EIA WB Mouse IgG1 Log in to see 474 4
0.0008854274 ABIN1107627 EIA IP Rat IgG1 Log in to see 9 5
0.0008854274 ABIN111064 EIA IHC (fro) WB Mouse IgG2b Log in to see H13 3
0.0008854274 ABIN181107 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 053A-1149-3-1-4 (1003) 2
0.0008854274 ABIN181106 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 10-02A 1
0.0008854274 ABIN181129 EIA FACS IHC (fro) Mouse IgG1 Log in to see 053A-514-3-1-4 2
0.0008854274 ABIN951635 EIA FACS WB Chicken Ig Log in to see Polyclonal 1
0.0008854274 ABIN113306 EIA WB HRP Sheep Log in to see Polyclonal 1
0.0008854274 ABIN784157 EIA IHC (fro) IHC (p) Sheep IgG Log in to see Polyclonal
0.0008854274 ABIN951634 EIA FACS WB HRP Chicken Ig Log in to see Polyclonal 1
0.0008854274 ABIN1106776 EIA IHC (fro) IHC (p) Mouse IgG2a Log in to see bH6 2
0.0008854274 ABIN568570 DB EIA ID IHC (fro) IF IP WB Biotin Goat IgG Log in to see Polyclonal
0.0008854274 ABIN568574 EIA ID IHC (fro) IF IP TRITC Goat IgG Log in to see Polyclonal
0.0008854274 ABIN568571 EIA ID IHC (fro) IF IP FITC Goat IgG Log in to see Polyclonal
0.0008854274 ABIN568572 DB EIA ID IHC (fro) IF IP WB HRP Goat IgG Log in to see Polyclonal

Top referenced anti-C3 antibody for Enzyme Immunoassay

Similar anti-C3 Antibodies

Application / Reactivity Human
Dot Blot (DB) 2 Antibodies
ELISA 119 Antibodies
Enzyme Immunoassay (EIA) 29 Antibodies
Flow Cytometry (FACS) 26 Antibodies
Immunoassay (IA) 5 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunodiffusion (ID) 12 Antibodies
Immunoelectrophoresis (IEP) 1 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 17 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 36 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 17 Antibodies
Immunoturbidimetry (IT) 1 Antibodies
Labeling (Lbl) 1 Antibodies
Radial Immunodiffusion (RID) 1 Antibodies
Radioimmunoassay (RIA) 4 Antibodies

General

Antigen Complement Component 3 (C3) Antibodies
Epitope C-Term
(13), (11), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human
(242), (65), (55), (18), (13), (5), (5), (5), (3), (2), (1)
Host Mouse
(140), (102), (86), (24), (13), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This C3 antibody is un-conjugated
(34), (31), (20), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(193), (187), (71), (67), (59), (45), (44), (42), (40), (35), (33), (24), (20), (5), (4), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-C3 Antibody

Target Details C3 Application Details Handling References for anti-C3 Antibody (ABIN1106781) Images
Sequence CARASHLGLA
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein G
Immunogen Peptide (last nine amino acids of C3a-desArg)
Clone 2898
Isotype IgG1

Target Details C3

Product Details anti-C3 Antibody Application Details Handling References for anti-C3 Antibody (ABIN1106781) Images back to top
Antigen
Alternative Name Complement C3 (C3 Antibody Abstract)
Background C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/mL. The complement system is an important part of the humoral response in innate immunity, consisting of three different pathways. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. Monoclonal antibodies detecting neo-epitopes have been used for direct quantification of activation at different steps in the complement cascade. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. An inherited deficiency of C3 predisposes the person to frequent assaults of bacterial infections. In ulcerative colitis, and idiopathic chronic inflammatory bowel disease, the deposition of C3 in the diseased mucosa has been reported. Proteolysis by certain enzymes results in the cleavage of C3 releasing C3a anaphylatoxin and C3b. C3a is a protein of 74 amino acids. C3a itself is very short-lived and in serum is cleaved rapidly into the more stable C3a-desArg (also called acylation stimulating protein, ASP). Therefore, measurement of C3a-desArg allows reliable conclusions about the level of complement activation in the test samples. C3a is a mediator of local inflammatory processes. It induces smooth muscle contraction, increases vascular permeability, and causes histamine release from mast cells and basophilic leukocytes. C3a is involved in inflammatory reactions seen in gram-negative bacterial sepsis, trauma, ischemic heart disease, post-dialysis syndrome and a variety of autoimmune diseases.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
Gene ID 9606
UniProt P01024
Research Area Complement Factors
Pathways Complement System

Application Details

Product Details anti-C3 Antibody Target Details C3 Handling References for anti-C3 Antibody (ABIN1106781) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-C3 Antibody Target Details C3 Application Details References for anti-C3 Antibody (ABIN1106781) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-C3 Antibody (ABIN1106781)

Product Details anti-C3 Antibody Target Details C3 Application Details Handling Images back to top
Background publications

Smalley, Root, Cho, Ross, Ley: "Proteomic discovery of 21 proteins expressed in human plasma-derived but not platelet-derived microparticles." in: Thrombosis and haemostasis, Vol. 97, Issue 1, pp. 67-80, 2007

Hartmann, Lübbers, Casaretto, Bautsch, Klos, Köhl: "Rapid quantification of C3a and C5a using a combination of chromatographic and immunoassay procedures." in: Journal of immunological methods, Vol. 166, Issue 1, pp. 35-44, 1993