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anti-Human C3 antibody for Flow Cytometry

Recommended C3 Antibody (supplied by: Log in to see )

Antigen
Complement Component 3 (C3) Antibodies
  • AHUS5
  • AI255234
  • ARMD9
  • asp
  • ASP
  • c3
  • C3
  • C3-1
  • C3a
  • C3b
  • C3d
  • c3_D
  • CPAMD1
  • cpamd1
  • HSE-MSF
  • Plp
  • sb:cb26
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11
Reactivity
Human
245
67
56
18
13
5
5
5
3
2
1
Host
Mouse
142
103
86
25
13
8
Clonality
Monoclonal
Conjugate
This C3 antibody is un-conjugated
34
31
20
6
6
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
195
191
71
70
61
47
45
42
42
35
33
26
22
5
4
1
1
1
1
1
1
1
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Catalog No. ABIN317012
$ 731.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010482287 ABIN181107 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 053A-1149-3-1-4 (1003) 2
0.0010482287 ABIN181106 EIA FACS IHC (fro) WB Mouse IgG1 Log in to see 10-02A 1
0.0010482287 ABIN181129 EIA FACS IHC (fro) Mouse IgG1 Log in to see 053A-514-3-1-4 2
0.0010482287 ABIN951635 EIA FACS WB Chicken Ig Log in to see Polyclonal 1
0.0010482287 ABIN308050 FACS ELISA FITC Mouse IgG1 Log in to see 6C9
0.0010482287 ABIN951634 EIA FACS WB HRP Chicken Ig Log in to see Polyclonal 1
0.0010482287 ABIN308054 FACS ELISA PE Mouse IgG1 Log in to see 10C7
0.0010482287 ABIN308052 FACS ELISA Biotin Mouse IgG1 Log in to see 10C7
0.0010482287 ABIN308049 FACS ELISA Biotin Mouse IgG1 Log in to see 6C9
0.0010482287 ABIN308053 FACS FITC Mouse IgG1 Log in to see 10C7
0.0010482287 ABIN308051 FACS ELISA PE Mouse IgG1 Log in to see 6C9
0.0010482287 ABIN212862 FACS ELISA Mouse IgG1 Log in to see 6C9
0.0010482287 ABIN212863 FACS ELISA Mouse IgG1 Log in to see 10C7
0.0010482287 ABIN601079 IHC (fro) FACS ELISA WB Mouse IgG2b Log in to see 013III-1-16
0.0010482287 ABIN601081 IHC (fro) FACS IHC (p) ELISA WB Mouse IgG1 Log in to see
0.0010482287 ABIN601082 IHC (fro) FACS IHC (p) ELISA Mouse IgG1 Log in to see
0.0010482287 ABIN2191942 IA FACS WB Mouse IgG1 Log in to see 755 2
0.0010482287 ABIN965475 FACS IP Lbl IHC ELISA WB Goat Log in to see
0.0010482287 ABIN2477804 IHC (fro) FACS ELISA Mouse IgG1 Log in to see 053A-514-3-1-4 2
0.0010482287 ABIN206674 FACS IHC (fro) ELISA Mouse IgG1 Log in to see

Top referenced anti-C3 antibody for Flow Cytometry

Similar anti-C3 Antibodies

Application / Reactivity Human
Dot Blot (DB) 2 Antibodies
ELISA 119 Antibodies
Enzyme Immunoassay (EIA) 29 Antibodies
Flow Cytometry (FACS) 26 Antibodies
Immunoassay (IA) 5 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunodiffusion (ID) 12 Antibodies
Immunoelectrophoresis (IEP) 1 Antibodies
Immunofluorescence (IF) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 17 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 36 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 18 Antibodies
Immunoturbidimetry (IT) 1 Antibodies
Labeling (Lbl) 1 Antibodies
Radial Immunodiffusion (RID) 1 Antibodies
Radioimmunoassay (RIA) 4 Antibodies

General

Antigen Complement Component 3 (C3) Antibodies
Reactivity Human
(245), (67), (56), (18), (13), (5), (5), (5), (3), (2), (1)
Host Mouse
(142), (103), (86), (25), (13), (8)
Clonality (Clone)
Monoclonal   ( )
Conjugate This C3 antibody is un-conjugated
(34), (31), (20), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(195), (191), (71), (70), (61), (47), (45), (42), (42), (35), (33), (26), (22), (5), (4), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-C3 Antibody

Target Details C3 Application Details Handling References for anti-C3 Antibody (ABIN317012) Images
Specificity AM05608PU-N Recognises 42 kDa inactive complement component 3b (iC3b) neoantigen present in blood serum.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Characteristics Synonyms: CPAMD1, Complement component 3, C3 and PZP-like alpha-2-macroglobulindomain-containing protein 1
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Purified Human iC3b
Clone 013III-1-16
Isotype IgG2b

Target Details C3

Product Details anti-C3 Antibody Application Details Handling References for anti-C3 Antibody (ABIN317012) Images back to top
Antigen
Alternative Name Complement C3 (C3 Antibody Abstract)
Background Cleavage of C3b into iC3b by the protease factor I, in the presence of cofactors, changes the structure and resulting binding properties, preventing binding by complement factor B and properdin. This prevents further progression of the complement pathway, providing another mechanism by which the complement pathway may be regulated. iC3b is thought to play a role in inducing tolerance, binding complement receptor type 3 on antigen presenting cells and stimulating them to produce transforming growth factor beta2 and interleukin-10. It is thought to stimulate B-cells via the CD21 receptor providing a link between the innate and adaptive immune responses. Additionally iC3b acts as an opsonin which is recognised by complement receptor 3 expressed on leukocytes or complement receptor of the immunoglobulin superfamily (CRIg) on Kupffer cells, stimulating phagocytosis of the tagged cells. iC3b levels are often elevated in diseases such as Systemic Lupus Erythematosis and Rheumatoid arthritis.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
Gene ID 718
UniProt P01024
Research Area Complement Factors
Pathways Complement System

Application Details

Product Details anti-C3 Antibody Target Details C3 Handling References for anti-C3 Antibody (ABIN317012) Images back to top
Application Notes ELISA. Western blot. Flow cytometry. Immunohistochemistry on Frozen Sections. Histology Positive Control Tissue: Kidney from post streptoccal glomerulonephritispatients.
Restrictions For Research Use only

Handling

Product Details anti-C3 Antibody Target Details C3 Application Details References for anti-C3 Antibody (ABIN317012) Images back to top
Concentration 1.0 mg/mL
Buffer Borate buffered saline pH 8.2-8.4, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-C3 Antibody (ABIN317012)

Product Details anti-C3 Antibody Target Details C3 Application Details Handling Images back to top
Background publications

Janssen, Gros: "Structural insights into the central complement component C3." in: Molecular immunology, Vol. 44, Issue 1-3, pp. 3-10, 2006

Bergmann-Leitner, Leitner, Tsokos: "Complement 3d: from molecular adjuvant to target of immune escape mechanisms." in: Clinical immunology (Orlando, Fla.), Vol. 121, Issue 2, pp. 177-85, 2006

Sohn, Bora, Suk, Molina, Kaplan, Bora: "Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells." in: Nature medicine, Vol. 9, Issue 2, pp. 206-12, 2003