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anti-Human C3 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended C3 Antibody (supplied by: Log in to see )

Antigen
Complement Component 3 (C3) Antibodies
  • C3
  • C3-1
  • sb:cb26
  • si:dkey-76b14.4
  • wu:fi34b03
  • wu:fj86e11
  • asp
  • cpamd1
  • AI255234
  • ASP
  • HSE-MSF
  • Plp
  • AHUS5
  • ARMD9
  • C3a
  • C3b
  • CPAMD1
  • C3d
  • c3
  • c3_D
  • complement component c3a
  • complement component 3
  • complement C3-like
  • complement component C3
  • endogenous retrovirus group K, member 13
  • c3a
  • C3
  • c3
  • LOC100060539
  • c3-1
  • ERVK-13
Epitope
AA 1611-1631
16
14
6
6
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
264
72
60
14
7
6
5
4
3
1
1
1
Host
Rabbit
134
109
91
25
14
8
Clonality
Polyclonal
Conjugate
This C3 antibody is un-conjugated
31
29
18
5
5
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
194
182
69
64
60
52
45
42
42
38
35
24
11
5
4
3
2
2
2
1
1
1
1
1
1
1
1
Options
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Catalog No. ABIN681913
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN885903 IF (p) Alexa Fluor 488 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN885905 IF (p) Alexa Fluor 350 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN885906 IF (p) Alexa Fluor 647 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN885904 IF (p) Alexa Fluor 555 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN2811825 IF (p) Alexa Fluor 594 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN2811826 IF (p) Alexa Fluor 594 Rabbit IgG AA 660-710 Log in to see Polyclonal
1 ABIN681918 IF (p) Cy5.5 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN681916 IF (p) Cy3 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN681919 IF (p) Cy7 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN681917 IF (p) Cy5 Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN681920 IF (p) FITC Rabbit IgG AA 1611-1631 Log in to see Polyclonal
1 ABIN1396857 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN1396859 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1396856 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN1396861 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN1396858 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1414733 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN1414734 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN1414735 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1414732 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal

Top referenced anti-C3 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-C3 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
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Cytometry by Time of Flight (CyTOF) 2 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies
Western Blotting (WB) 123 Antibodies 48 Antibodies 18 Antibodies
Turbidimetry (TB) 2 Antibodies
Thin Layer Immunoassay (TIA) 1 Antibodies
Radioimmunoassay (RIA) 3 Antibodies
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General

Antigen Complement Component 3 (C3) Antibodies
Epitope AA 1611-1631
(16), (14), (6), (6), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(264), (72), (60), (14), (7), (6), (5), (4), (3), (1), (1), (1)
Host Rabbit
(134), (109), (91), (25), (14), (8)
Clonality
Polyclonal
Conjugate This C3 antibody is un-conjugated
(31), (29), (18), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(194), (182), (69), (64), (60), (52), (45), (42), (42), (38), (35), (24), (11), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-C3 Antibody

Target Details C3 Application Details Handling References for anti-C3 Antibody (ABIN681913) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Complement C3 alpha chain
Isotype IgG

Target Details C3

Product Details anti-C3 Antibody Application Details Handling References for anti-C3 Antibody (ABIN681913) Images back to top
Antigen
Alternative Name Complement C3 (C3 Antibody Abstract)
Background

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2 (PubMed:837664, PubMed:29953, PubMed:959512, PubMed:1432298, PubMed:15833747, PubMed:16333141, PubMed:1961575).

Subcellular location: Secreted


Synonyms: ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1, HEL-S-62p, Complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3
Gene ID 718
UniProt P01024
Research Area Complement Factors
Pathways Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling

Application Details

Product Details anti-C3 Antibody Target Details C3 Handling References for anti-C3 Antibody (ABIN681913) Images back to top
Application Notes IHC-P(1:100-500), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-C3 Antibody Target Details C3 Application Details References for anti-C3 Antibody (ABIN681913) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-C3 Antibody (ABIN681913)

Product Details anti-C3 Antibody Target Details C3 Application Details Handling Images back to top
Product cited in:

Zhuang, Han, Li, Kienhöfer, Lee, Shumyak, Meyerholz, Rosadzinski, Rosner, Chan, Xu, Segal, Sobel, Yang, Hoffmann, Reeves: "A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 68, Issue 12, pp. 2917-2928, 2016

Trang, Hirai, Nabeta, Fuke, Yamaguchi: "Membranoproliferative glomerulonephritis in a calf with nephrotic syndrome." in: Journal of comparative pathology, Vol. 151, Issue 2-3, pp. 162-5, 2014

Images

Product Details anti-C3 Antibody Target Details C3 Application Details Handling References for anti-C3 Antibody (ABIN681913) back to top
Supplier Images
Immunofluorescence (IF) image for anti-C3 antibody (Complement Component 3) (AA 1611-1631) (ABIN681913) Formalin-fixed and paraffin embedded rat liver labeled with Anti-C3 Polyclonal Antibo...
Immunofluorescence (IF) image for anti-C3 antibody (Complement Component 3) (AA 1611-1631) (ABIN681913) Formalin-fixed and paraffin embedded mouse kidney labeled with Anti-C3 Polyclonal Ant...
ELISA image for anti-C3 antibody (Complement Component 3) (AA 1611-1631) (ABIN681913) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...