anti-Human CD59 antibody for Immunocytochemistry

Recommended CD59 Antibody (supplied by: Log in to see )

Antigen
CD59 Antibodies
  • 16.3A5
  • 1F5
  • EJ16
  • EJ30
  • EL32
  • G344
  • HRF-20
  • HRF20
  • MAC-IP
  • MACIF
  • MEM43
  • MIC11
  • MIN1
  • MIN2
  • MIN3
  • MIRL
  • MSK21
  • p18-20
  • Cd59a
  • Cd59b
  • MACIP
  • AA987121
  • Cd59
  • protectin
  • CD59 molecule, complement regulatory protein
  • CD59a antigen
  • CD59b antigen
  • CD59
  • Cd59
  • Cd59a
  • Cd59b
Epitope
AA 31-111
20
15
11
10
10
9
7
7
6
5
5
5
4
3
2
1
1
Reactivity
Human
510
43
38
23
17
14
9
8
2
2
1
1
Host
Mouse
408
125
41
7
1
Clonality
Monoclonal
Conjugate
This CD59 antibody is un-conjugated
63
53
44
14
12
12
12
11
11
10
10
10
10
10
10
10
6
6
5
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
423
207
193
129
112
90
83
47
44
25
13
9
8
4
3
2
1
1
1
1
1
1
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Catalog No. ABIN1098134
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1491388 ELISA FACS ICC IF IHC (p) WB Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN260113 Func ICC FACS IHC (fro) IF IHC (p) IHC WB Rat IgG2b Log in to see YTH53-1
1 ABIN4880618 ELISA FACS ICC IHC WB Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN4294895 CyTOF ELISA FACS ICC IF IHC WB Mouse IgG1 Log in to see 8D2B8
1 ABIN1174495 ICC IHC IP WB Rabbit IgG AA 26-102 Log in to see Polyclonal
1 ABIN5625552 ELISA FACS ICC IF IHC WB Alexa Fluor 700 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625554 ELISA ICC IF IHC WB Biotin Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625556 ELISA FACS ICC IF IHC WB DyLight 405 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625558 ELISA FACS ICC IF IHC WB DyLight 550 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625559 ELISA FACS ICC IF IHC WB DyLight 650 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625557 ELISA FACS ICC IF IHC WB DyLight 488 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625549 ELISA FACS ICC IF IHC WB Alexa Fluor 405 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625551 ELISA FACS ICC IF IHC WB Alexa Fluor 647 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625550 ELISA FACS ICC IF IHC WB Alexa Fluor 488 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625555 ELISA FACS ICC IF IHC WB DyLight 350 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625560 ELISA FACS ICC IF IHC WB DyLight 680 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625561 ELISA FACS ICC IF IHC WB DyLight 755 Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN5625562 ELISA FACS ICC IF IHC FITC Mouse IgG1 AA 31-111 Log in to see 8D2B8
1 ABIN4295045 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 405 Rat IgG2b Log in to see YTH53-1
1 ABIN4295054 FACS ICC IF IHC (fro) IHC (p) WB DyLight 488 Rat IgG2b Log in to see YTH53-1

General

Antigen CD59 Antibodies
Epitope AA 31-111
(20), (15), (11), (10), (10), (9), (7), (7), (6), (5), (5), (5), (4), (3), (2), (1), (1)
Reactivity Human
(510), (43), (38), (23), (17), (14), (9), (8), (2), (2), (1), (1)
Host Mouse
(408), (125), (41), (7), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD59 antibody is un-conjugated
(63), (53), (44), (14), (12), (12), (12), (11), (11), (10), (10), (10), (10), (10), (10), (10), (6), (6), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(423), (207), (193), (129), (112), (90), (83), (47), (44), (25), (13), (9), (8), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CD59 Antibody

Target Details CD59 Application Details Handling References for anti-CD59 antibody (ABIN1098134) Images
Purification Purified
Immunogen Purified recombinant fragment of human CD59 (AA 31-111) expressed in E. Coli.
Clone 8D2B8
Isotype IgG1

Target Details CD59

Product Details anti-CD59 Antibody Application Details Handling References for anti-CD59 antibody (ABIN1098134) Images back to top
Antigen
Alternative Name CD59 (CD59 Antibody Abstract)
Background This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. , ,
Molecular Weight 14.2 kDa
Gene ID 966
HGNC 966
Research Area Cardiovascular, Atherosclerosis, Hematopoietic Progenitors, Tyrosine Kinases, Innate Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways Complement System

Application Details

Product Details anti-CD59 Antibody Target Details CD59 Handling References for anti-CD59 antibody (ABIN1098134) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:50 -1:200, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-CD59 Antibody Target Details CD59 Application Details References for anti-CD59 antibody (ABIN1098134) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-CD59 antibody (ABIN1098134)

Product Details anti-CD59 Antibody Target Details CD59 Application Details Handling Images back to top
Product cited in:

Alegretti, Mucenic, Merzoni, Faulhaber, Silla, Xavier: "Expression of CD55 and CD59 on peripheral blood cells from systemic lupus erythematosus (SLE) patients." in: Cellular immunology, Vol. 265, Issue 2, pp. 127-32, 2010

Ma, Chang, Qin, Sun, Huang, He: "Decreased expression of complement regulatory proteins, CD55 and CD59, on peripheral blood leucocytes in patients with type 2 diabetes and macrovascular diseases." in: Chinese medical journal, Vol. 122, Issue 18, pp. 2123-8, 2009

Images

Product Details anti-CD59 Antibody Target Details CD59 Application Details Handling References for anti-CD59 antibody (ABIN1098134) back to top
Supplier Images
ELISA image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 2: Flow cytometric analysis of HeLa cells using CD59 mouse mAb (green) and neg...
Immunocytochemistry (ICC) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 3: Immunofluorescence analysis of Hela cells using CD59 mouse mAb (green) . Bl...
Immunocytochemistry (ICC) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 4: Immunofluorescence analysis of MCF-7 cells using CD59 mouse mAb (green) . B...
Immunohistochemistry (IHC) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 5: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues us...
Immunohistochemistry (IHC) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues...
Western Blotting (WB) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 7: Western blot analysis using CD59 mAb against human CD59 recombinant protein...
Western Blotting (WB) image for anti-CD59 (CD59) (AA 31-111) antibody (ABIN1098134) Figure 8: Western blot analysis using CD59 mAb against HEK293 (1) and CD59 (AA: 31-11...