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anti-Human CD59 antibody for Blocking Antibody

Recommended CD59 Antibody (supplied by: Log in to see )

Antigen
CD59 Antibodies
  • 1F5
  • 16.3A5
  • AA987121
  • Cd59
  • Cd59a
  • Cd59b
  • EJ16
  • EJ30
  • EL32
  • G344
  • HRF-20
  • HRF20
  • MAC-IP
  • MACIF
  • MACIP
  • MEM43
  • MIC11
  • MIN1
  • MIN2
  • MIN3
  • MIRL
  • MSK21
  • p18-20
  • protectin
Reactivity
Human
503
36
33
24
17
15
9
7
2
2
1
1
Host
Mouse
405
110
44
7
1
Clonality
Monoclonal
Conjugate
This CD59 antibody is un-conjugated
63
58
44
14
11
11
10
9
9
9
9
9
9
9
9
9
9
5
5
1
1
1
1
1
1
1
1
1
Application
Blocking Antibody (Inhibition), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
417
194
187
103
97
96
73
48
34
32
11
6
5
3
2
2
Supplier
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Catalog No. ABIN2191998
$ 555.23
Plus shipping costs $45.00

Top referenced anti-CD59 antibody for Blocking Antibody

Similar anti-CD59 Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 1 Antibodies
ELISA 69 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 393 Antibodies
Functional Studies (Func) 31 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 27 Antibodies
Immunofluorescence (IF) 73 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 89 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 6 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 41 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 187 Antibodies
Immunoprecipitation (IP) 80 Antibodies

General

Antigen CD59 Antibodies
Reactivity Human
(503), (36), (33), (24), (17), (15), (9), (7), (2), (2), (1), (1)
Host Mouse
(405), (110), (44), (7), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD59 antibody is un-conjugated
(63), (58), (44), (14), (11), (11), (10), (9), (9), (9), (9), (9), (9), (9), (9), (9), (9), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Antibody (Inhibition), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(417), (194), (187), (103), (97), (96), (73), (48), (34), (32), (11), (6), (5), (3), (2), (2)
Pubmed 2 references available
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Product Details anti-CD59 Antibody

Target Details CD59 Application Details Handling References for anti-CD59 Antibody (ABIN2191998) Images
Sterility 0.2 μm filtered
Endotoxin Level Low endotoxin level
Clone MEM-43

Target Details CD59

Product Details anti-CD59 Antibody Application Details Handling References for anti-CD59 Antibody (ABIN2191998) Images back to top
Antigen
Alternative Name CD59 (CD59 Antibody Abstract)
Background The antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitope (W40, R-53) on CD59 Molecule.
Pathways Complement System

Application Details

Product Details anti-CD59 Antibody Target Details CD59 Handling References for anti-CD59 Antibody (ABIN2191998) Images back to top
Application Notes For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts endotoxin to be inactivated.
Restrictions For Research Use only

Handling

Product Details anti-CD59 Antibody Target Details CD59 Application Details References for anti-CD59 Antibody (ABIN2191998) Images back to top
Buffer PBS and 0.1 % bovine serum albumin with low endotoxin level.
Storage 4 °C
Storage Comment Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Expiry Date 12 months

References for anti-CD59 Antibody (ABIN2191998)

Product Details anti-CD59 Antibody Target Details CD59 Application Details Handling Images back to top
Product cited in:

Yamamoto, Nakane, Doi, Osaki: "Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14." in: Cellular signalling, Vol. 15, Issue 9, pp. 861-9, 2003

Background publications

Cebecauer, Cerný, Horejsí: "Incorporation of leucocyte GPI-anchored proteins and protein tyrosine kinases into lipid-rich membrane domains of COS-7 cells." in: Biochemical and biophysical research communications, Vol. 243, Issue 3, pp. 706-10, 1998