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anti-Pig (Porcine) CD59 antibody for Functional Studies

Recommended CD59 Antibody (supplied by: Log in to see )

Antigen
CD59 Antibodies
  • 1F5
  • 16.3A5
  • AA987121
  • Cd59
  • Cd59a
  • Cd59b
  • EJ16
  • EJ30
  • EL32
  • G344
  • HRF-20
  • HRF20
  • MAC-IP
  • MACIF
  • MACIP
  • MEM43
  • MIC11
  • MIN1
  • MIN2
  • MIN3
  • MIRL
  • MSK21
  • p18-20
  • protectin
Reactivity
Human, Pig (Porcine)
340
22
19
9
9
7
2
2
2
1
1
Host
Mouse
248
109
25
7
1
Clonality
Monoclonal
Conjugate
This CD59 antibody is un-conjugated
57
48
38
10
9
2
2
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS)
244
138
96
78
76
70
31
29
16
14
11
6
5
3
2
2
1
Supplier
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Catalog No. ABIN120694
$ 286.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000873873 ABIN94204 Func FACS Mouse IgM Log in to see MEM-129 6
0.000873873 ABIN269160 Func FACS Mouse IgM Log in to see MEM-129
0.000873873 ABIN3199956 FACS Func Mouse IgM Log in to see MEM-129
0.000873873 ABIN3037467 Func FACS Mouse IgM Log in to see

Top referenced anti-CD59 antibody for Functional Studies

Similar anti-CD59 Antibodies

Application / Reactivity Pig (Porcine) Human
ELISA 4 Antibodies 68 Antibodies
Flow Cytometry (FACS) 5 Antibodies 241 Antibodies
Functional Studies (Func) 5 Antibodies 18 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies
Western Blotting (WB) 4 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies

General

Antigen CD59 Antibodies
Reactivity Human, Pig (Porcine)
(340), (22), (19), (9), (9), (7), (2), (2), (2), (1), (1)
Host Mouse
(248), (109), (25), (7), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD59 antibody is un-conjugated
(57), (48), (38), (10), (9), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS)
(244), (138), (96), (78), (76), (70), (31), (29), (16), (14), (11), (6), (5), (3), (2), (2), (1)
Pubmed 1 reference available
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Product Details anti-CD59 Antibody

Target Details CD59 Application Details Handling References for anti-CD59 Antibody (ABIN120694) Images
Specificity The antibody MEM-129 reacts with CD59 (Protectin).
Purification Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
Purity > 95 % (by SDS-PAGE).
Immunogen Human peripheral blood lymphocytes
Clone MEM-129
Isotype IgM

Target Details CD59

Product Details anti-CD59 Antibody Application Details Handling References for anti-CD59 Antibody (ABIN120694) Images back to top
Antigen
Alternative Name CD59 (CD59 Antibody Abstract)
Background CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
Gene ID 966
UniProt P13987
Research Area Cardiovascular, Atherosclerosis, Hematopoietic Progenitors, Tyrosine Kinases, Innate Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways Complement System

Application Details

Product Details anti-CD59 Antibody Target Details CD59 Handling References for anti-CD59 Antibody (ABIN120694) Images back to top
Application Notes Flow Cytometry. Functional Studies (The antibody activates T-cells).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CD59 Antibody Target Details CD59 Application Details References for anti-CD59 Antibody (ABIN120694) Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
Preservative Azide free
Storage 4 °C
Storage Comment Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch.
Expiry Date 12 months

References for anti-CD59 Antibody (ABIN120694)

Product Details anti-CD59 Antibody Target Details CD59 Application Details Handling Images back to top
Background publications

Pizzo, Giurisato, Tassi, Benedetti, Pozzan, Viola: "Lipid rafts and T cell receptor signaling: a critical re-evaluation." in: European journal of immunology, Vol. 32, Issue 11, pp. 3082-91, 2003