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Browse our CD59 (CD59) ELISA Kits

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CD59 ELISA Kits (CD59)
On are 40 CD59 ELISA Kits from 8 different suppliers available. Additionally we are shipping CD59 Antibodies (391) and CD59 Proteins (34) and many more products for this protein. A total of 475 CD59 products are currently listed.
1F5, 16.3A5, AA987121, Cd59, Cd59a, Cd59b, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MACIP, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin

More ELISA Kits for CD59 Interaction Partners

Human CD59 interaction partners

  1. Decreased CD59 expression in threatened miscarriage at late gestational ages leads to additional activation of a maternal immune response and serves as a possible predictor for premature birth.

  2. Data show that the palmitoylation mutation of linker for activation of T cells (LAT (show LAT ELISA Kits))attenuated the signal transduction induced by glycosylphosphatidylinositol-anchored CD59 antigen in T cells.

  3. After blockage of CD59 function, the reactive Abs, regardless of their neutralizing activities, significantly enhanced specific ADCML of HIV-1 virions

  4. Genetic risk at the CFH (show CFH ELISA Kits)-to-F13B (show F13B ELISA Kits) locus was associated with higher levels of complement activation at the human macular RPE-choroid interface, as was cigarette smoking. Levels of CRP (show CRP ELISA Kits) were substantially elevated in risk donors with smoking history.

  5. A primary homozygous Cys89Tyr CD59 deficiency in humans resulted in the amino acid substitution p.Cys89Tyr with ensuing failure of proper localization of the CD59 protein to the cell surface. (Review)

  6. Increased CD59 protein expression is associated with the outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP (show DDIT3 ELISA Kits) antineoplastic protocol.

  7. Data suggest that microRNA-224 directly down-regulates CD59 antigen expression in diffuse large B-cell lymphoma by binding to CD59 3'-untranslated region.

  8. Expression of membrane complement regulators, CD46 (show CD46 ELISA Kits), CD55 (show CD55 ELISA Kits) and CD59, in mesothelial cells of patients on peritoneal dialysis therapy.

  9. The presence of CD55 (show CD55 ELISA Kits)- and/or CD59-deficient erythrocytic populations in patients with rheumatic diseases reflects an immune-mediated bone-marrow derived phenomenon.

  10. Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells.

Pig (Porcine) CD59 interaction partners

  1. Data demonstrate that the resistance of neonatal porcine Sertoli cells to human xenoantibody and complement-mediated lysis is associated with low expression of xenoantigen alpha-Gal and high production of the complement inhibitors clusterin (show CLU ELISA Kits) and CD59.

Mouse (Murine) CD59 interaction partners

  1. Varicella-zoster virus infection upregulates host CD59 expression in a tissue-specific manner.

  2. This study support a role of Cd59a in controlling the innate immune status of the RPE-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging

  3. results implicate CD59 as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology.

  4. Soluble forms of CD59 (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration.

  5. both CD59 and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells

  6. CD59a inhibits systemic autoimmunity in MRL/lpr (show FAS ELISA Kits) mice through a complement-independent mechanism.

  7. While the connection between CFH (show CFH ELISA Kits) deficiency and failure to upregulate CD59a remains unknown, these results suggest that expression of CD59 is tissue-specific and that neuroretinal regulation depends on CFH (show CFH ELISA Kits).

  8. Actively immunized experimental autoimmune myasthenia gravis mice deficient in either CD55 (show CD55 ELISA Kits) or CD59 showed significant differences in adaptive immune responses and worsened disease outcome associated with increased levels of serum cytokines, modified production of acetylcholine receptor (show CHRNB1 ELISA Kits) antibodies, and more complement deposition at the neuromuscular junction.

  9. HBx can up-regulate CD59 and Crry (show CR1L ELISA Kits) expression in podocytes through activating the P38 (show CRK ELISA Kits) pathway.

  10. CD59 has a role in growth of the choroidal neovascular complex in mice

CD59 Antigen Profile

Antigen Summary

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Alternative names and synonyms associated with CD59

  • CD59 molecule, complement regulatory protein (CD59) Elisa Kit
  • CD59 molecule, complement regulatory protein (Cd59) Elisa Kit
  • CD59a antigen (Cd59a) Elisa Kit
  • CD59b antigen (Cd59b) Elisa Kit
  • 1F5 Elisa Kit
  • 16.3A5 Elisa Kit
  • AA987121 Elisa Kit
  • Cd59 Elisa Kit
  • Cd59a Elisa Kit
  • Cd59b Elisa Kit
  • EJ16 Elisa Kit
  • EJ30 Elisa Kit
  • EL32 Elisa Kit
  • G344 Elisa Kit
  • HRF-20 Elisa Kit
  • HRF20 Elisa Kit
  • MAC-IP Elisa Kit
  • MACIF Elisa Kit
  • MACIP Elisa Kit
  • MEM43 Elisa Kit
  • MIC11 Elisa Kit
  • MIN1 Elisa Kit
  • MIN2 Elisa Kit
  • MIN3 Elisa Kit
  • MIRL Elisa Kit
  • MSK21 Elisa Kit
  • p18-20 Elisa Kit
  • protectin Elisa Kit

Protein level used designations for CD59 (CD59) ELISA Kits

1F5 antigen , 20 kDa homologous restriction factor , CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) , CD59 glycoprotein , Ly-6-like protein , MEM43 antigen , T cell-activating protein , human leukocyte antigen MIC11 , lymphocytic antigen CD59/MEM43 , membrane attack complex (MAC) inhibition factor , membrane attack complex inhibition factor , membrane inhibitor of reactive lysis , protectin , surface anitgen recognized by monoclonal antibody 16.3A5 , MAC-IP , MAC-inhibitory protein , MACIF , CD59 antigen , CD59b moleucle, complement regulatory protein , Cb59b molecule , CD59 homolog , CD59A glycoprotein , CD59B glycoprotein

966 Homo sapiens
397347 Sus scrofa
25407 Rattus norvegicus
739046 Pan troglodytes
100009459 Oryctolagus cuniculus
101102670 Ovis aries
100173870 Pongo abelii
12509 Mus musculus
333883 Mus musculus
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