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|Antigen||Complement Factor P (CFP) Antibodies|
|Conjugate||This CFP antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
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Product Details anti-CFP AntibodyTarget Details CFP Application Details Handling Images
|Specificity||This antibody recognises human factor P, a 53 kDa glycosylated protein present in blood serum.|
|Characteristics||Synonyms: CFP, PFC, Complement factor P|
|Purification||Affinity chromatography on Protein A|
|Immunogen||Native purified factor P from human serum.|
Target Details CFPProduct Details anti-CFP Antibody Application Details Handling Images back to top
|Alternative Name||Properdin (CFP Antibody Abstract)|
|Background||Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.Synonyms: CFP, Complement factor P, PFC|
Application DetailsProduct Details anti-CFP Antibody Target Details CFP Handling Images back to top
ELISA. Functional Assays. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CFP Antibody Target Details CFP Application Details Images back to top
|Buffer||Borate buffered saline pH 8.2 containing 0.02 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|