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Browse our anti-Complement Factor B (CFB) Antibodies

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anti-Complement Factor B Antibodies (CFB)
On are 194 Complement Factor B (CFB) Antibodies from 18 different suppliers available. Additionally we are shipping Complement Factor B Kits (73) and Complement Factor B Proteins (31) and many more products for this protein. A total of 301 Complement Factor B products are currently listed.
AHUS4, AI195813, AI255840, B, BF, Bf-1, bf/c2, Bf B, bfb-A, BFD, Brre-Bf, C2, CFAB, CFB, Da1-24, Fb, FBI12, fc04c04, GBG, H2-Bf, LOC397725, PBF2, Sp152, wu:fc04c04, zgc:114032
list all antibodies Gene Name GeneID UniProt
CFB 362749 Q5XIM4
CFB 629 P00751
CFB 14962  

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anti-Rat (Rattus) Complement Factor B Antibodies:

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anti-Mouse (Murine) Complement Factor B Antibodies:

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Top referenced anti-Complement Factor B Antibodies

  1. Human Monoclonal Complement Factor B Primary Antibody for EIA, Func - ABIN181128 : Xu, Narayana, Volanakis: Structural biology of the alternative pathway convertase. in Immunological reviews 2001 (PubMed)
    Show all 2 references for ABIN181128

  2. Human Monoclonal Complement Factor B Primary Antibody for EIA, IP - ABIN1106808 : Oppermann, Kurts, Zierz, Quentin, Weber, Götze: Elevated plasma levels of the immunosuppressive complement fragment Ba in renal failure. in Kidney international 1992 (PubMed)

More Antibodies against Complement Factor B Interaction Partners

Human Complement Factor B (CFB) interaction partners

  1. CFB is downregulated in non-small cell lung cancer patients compared to those with benign lung disease or no lung disease.

  2. individuals with the chronic hepatitis B (CHB) risk genotype CC of rs12614 had significantly lower CFB concentrations than those carrying one or two rs12614 T alleles (CT or TT carriers) both in normal populations and CHB patients

  3. Complement factor B is a novel biomarker candidate for pancreatic ductal adenocarcinoma.

  4. complement factor B has an important role in the etiology of familial C3 glomerulonephritis

  5. A mutation in complement factor B was associated with a case of C3 glomerulonephritis.

  6. The C2 and CFB gene variants were shown to be associated with polypoidal CNV. Typical PCV was not associated with variants in these genes.

  7. Complement factor B is potently upregulated locally in inflammatory bowel disease in addition to having a possible central role in systemic complement activation.

  8. ARMS2 (show ARMS2 Antibodies) and C3 are major contributors to advanced age-related macular degeneration in Mexican patients, while the contributions of CFH (show CFH Antibodies), C2, and CFB are minor to those of other populations.

  9. The CFB (R32Q) polymorphism was associated with age-related macular degeneration characterized by small drusen only, and appeared to be protective of large drusen.

  10. we have assessed the relationship between GA and previously identified AMD (show AMD1 Antibodies)-associated variants of genes (CFH (show CFH Antibodies), CFB, C3, FHR1 (show CFHR1 Antibodies), FRH3, and ARMS2 (show ARMS2 Antibodies)/HTRA (show HTRA1 Antibodies)).

Mouse (Murine) Complement Factor B (CFB) interaction partners

  1. AP inhibitors not only prevent, but have the potential to accelerate the clearance of complement-mediated ocular injury. Improving our understanding of the regulation of the AP is paramount to developing novel treatment approaches for AMD (show AMD1 Antibodies).

  2. The roles of C3, CfB, and C3a (show C3 Antibodies) receptor in the severity of S. aureus induced septic arthritis are reported.

  3. Study shows that Factor B regulates UVA and UVB induced immunosuppression, UV induced edema and mast cell infiltration into the skin

  4. Mouse RPE (show RPE Antibodies) cells express and secrete CFB sufficient to promote RPE (show RPE Antibodies) damage and CNV.

  5. Properdin-deficient mice developed less severe collagen-antibody-induced arthritis than did wild-type mice.

  6. Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6 (show IL6 Antibodies)-dependent manner.

  7. A2E accumulation altered retinal microglial complement regulation by increasing complement factor B (and decreasing complement factor H (show CFH Antibodies) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  8. study found that Streptococcus pneumoniae induced increased gene expression of factor B of the alternative complement pathway and C3 in mouse middle ear epithelium

  9. TLR4 (show TLR4 Antibodies) stimulation or activation of RNA-sensing mechanisms results in synthesis and release of factor B by macrophages through distinct but overlapping mechanisms

  10. Study identified novel mutations in CFH (show CFH Antibodies), CFHR5 (show CFHR5 Antibodies), CFI (show CFI Antibodies), CFB and C3 in American patients with atypical hemolytic uremic syndrome.

Complement Factor B (CFB) Antigen Profile

Antigen Summary

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Alternative names and synonyms associated with Complement Factor B (CFB)

  • complement factor B (CFB) antibody
  • complement factor B (cfb) antibody
  • complement factor B (Bf) antibody
  • complement factor B (bfb-A) antibody
  • complement factor B (LOC397725) antibody
  • zgc:158446 (zgc:158446) antibody
  • complement factor B (bf/c2) antibody
  • ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) (Atp5s) antibody
  • complement factor B (Cfb) antibody
  • complement factor B-like (LOC100355944) antibody
  • AHUS4 antibody
  • AI195813 antibody
  • AI255840 antibody
  • B antibody
  • BF antibody
  • Bf-1 antibody
  • bf/c2 antibody
  • Bf B antibody
  • bfb-A antibody
  • BFD antibody
  • Brre-Bf antibody
  • C2 antibody
  • CFAB antibody
  • CFB antibody
  • Da1-24 antibody
  • Fb antibody
  • FBI12 antibody
  • fc04c04 antibody
  • GBG antibody
  • H2-Bf antibody
  • LOC397725 antibody
  • PBF2 antibody
  • Sp152 antibody
  • wu:fc04c04 antibody
  • zgc:114032 antibody

Protein level used designations for CFB

complement component factor B , complement factor B , complement component 2 , complement factor Bf-1 , ATP synthase subunit s, mitochondrial , ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) , ATP synthase-coupling factor B , Factor B , mitochondrial ATP synthase regulatory component factor B , B-factor, properdin , C3 proaccelerator , C3 proactivator , C3/C5 convertase , glycine-rich beta glycoprotein , glycine-rich beta-glycoprotein , properdin factor B , alternative-complement pathway C3/C5 convertase , complement component 2 (within H-2S) , histocompatibility 2, complement component factor B , properdin , EC-VMFB

716809 Macaca mulatta
30604 Danio rerio
373308 Strongylocentrotus purpuratus
373577 Xenopus laevis
397725 Xenopus laevis
792472 Danio rerio
100049430 Oryzias latipes
100136605 Oncorhynchus mykiss
100555981 Anolis carolinensis
362749 Rattus norvegicus
629 Homo sapiens
14962 Mus musculus
100688056 Canis lupus familiaris
100715616 Cavia porcellus
100124383 Sus scrofa
294257 Rattus norvegicus
514076 Bos taurus
101115072 Ovis aries
100051124 Equus caballus
494140 Pan troglodytes
100355944 Oryctolagus cuniculus
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