Browse our anti-Complement Factor H (CFH) Antibodies

Full name:
anti-Complement Factor H Antibodies (CFH)
On www.antibodies-online.com are 258 Complement Factor H (CFH) Antibodies from 27 different suppliers available. Additionally we are shipping Complement Factor H Kits (56) and Complement Factor H Proteins (18) and many more products for this protein. A total of 341 Complement Factor H products are currently listed.
Synonyms:
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2
list all antibodies Gene Name GeneID UniProt
CFH 12628 P06909
CFH 3075 P08603
CFH 155012  

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Most Popular Reactivities for anti-Complement Factor H (CFH) Antibodies

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anti-Mouse (Murine) Complement Factor H Antibodies:

anti-Human Complement Factor H Antibodies:

anti-Rat (Rattus) Complement Factor H Antibodies:

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Top referenced anti-Complement Factor H Antibodies

  1. Human Monoclonal Complement Factor H Primary Antibody for FACS - ABIN2660858 : Ripoche, Day, Harris, Sim: The complete amino acid sequence of human complement factor H. in The Biochemical journal 1988 (PubMed)
    Show all 6 references for 2660858

  2. Human Polyclonal Complement Factor H Primary Antibody for EIA, IF - ABIN951646 : Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement. in Infection and immunity 2010 (PubMed)
    Show all 3 references for 951646

  3. Human Polyclonal Complement Factor H Primary Antibody for IF, IHC (p) - ABIN654896 : Scambi, La Verde, De Franceschi, Barausse, Poli, Benedetti, Sorio, Deriu, Roncada, Bortolami, Turrini, Caramaschi, Stranieri, Bambara, Biasi: Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. in PLoS ONE 2010 (PubMed)
    Show all 2 references for 654896

  4. Human Monoclonal Complement Factor H Primary Antibody for EIA, FACS - ABIN181114 : Alexander, Quigg: The simple design of complement factor H: Looks can be deceiving. in Molecular immunology 2006 (PubMed)
    Show all 2 references for 181114

  5. Horse (Equine) Polyclonal Complement Factor H Primary Antibody for EIA, ID - ABIN113017 : Chung, Liszewski, Nybakken, Davis, Townsend, Fremont, Atkinson, Diamond: West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  6. Human Polyclonal Complement Factor H Primary Antibody for ID, WB - ABIN253380 : Radu, Hu, Yuan, Welch, Makshanoff, Lloyd, McMullen, Travis, Bok: Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration. in The Journal of biological chemistry 2011 (PubMed)

  7. Human Polyclonal Complement Factor H Primary Antibody for ELISA, WB - ABIN250548 : Klein, Zeiss, Chew, Tsai, Sackler, Haynes, Henning, SanGiovanni, Mane, Mayne, Bracken, Ferris, Ott, Barnstable, Hoh: Complement factor H polymorphism in age-related macular degeneration. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against Complement Factor H Interaction Partners

Chimpanzee Complement Factor H (CFH) interaction partners

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) interaction partners

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (show CFHR1 Antibodies)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) interaction partners

  1. environmental factors can drive retinal disease in these mice when linked to complement deficits impairing immune function. Both groups of mice had similar levels of retinal amyloid beta accumulation. Consequently there is no direct link between this and inflammation in Cfh(-/-) mice.

  2. absence of plasma CfH conferred susceptibility to glomerulonephritis

  3. This new understanding of the complicated interactions of CFH in AMD (show AMD1 Antibodies)-like pathology provides an improved foundation for the development of targeted therapies for AMD (show AMD1 Antibodies)

  4. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  5. Cfh and Cfhr2 (show CFHR2 Antibodies) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  6. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  7. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (show MASP1 Antibodies) did not ameliorate either the plasma Complement C3 (show C3 Antibodies) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  8. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (show CFB Antibodies) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  9. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (show C5AR1 Antibodies)(-/-) double knockout mice, highlighting the C5aR (show C5AR1 Antibodies) dependence.

  10. Properdin (show CFB Antibodies) deficiency exacerbated renal injury in mice lacking complement factor H.

Human Complement Factor H (CFH) interaction partners

  1. Data suggest that disease-linked mutations in complement factor H (CFH) affect pivotal role of CFH in regulation of complement activation; mutations studied include those linked to atypical hemolytic uremic syndrome and age-related macular degeneration.

  2. Fibrinogen gamma chain (show FGG Antibodies) and complement factor H were found to be bound as a protein complex in the plasma of a patient with advanced ovarian cancer

  3. Factor I binds C3b-Factor H between Factor H domains 2 and 3 and a reoriented C3b C-terminal domain and docks onto the first scissile bond, while stabilizing its catalytic domain for proteolytic activity.

  4. The VEGF (show VEGFA Antibodies) haplotype TGA (show TBX1 Antibodies) could be used as a marker for poor visual prognosis in Tunisian patients with neovascular AMD (show AMD1 Antibodies) treated with bevacizumab.

  5. Two protective, low-frequency, non-synonymous variants were significantly associated with a decrease in age-related macular degeneration (AMD (show AMD1 Antibodies))risk: A307V in PELI3 (show PELI3 Antibodies) and N1050Y in CFH .We also identified a strong protective signal for a common variant (rs8056814) near CTRB1 (show CTRB1 Antibodies) associated with a decrease in AMD (show AMD1 Antibodies) risk (logistic regression: OR = 0.71, P = 1.8 x 10-07).

  6. this study shows that RNA interference of factor H in dendritic cells increased alloantigen-specific T-cell proliferation

  7. monomeric CRP (show CRP Antibodies) (mCRP) but not the pentameric form (pCRP) upregulates IL-8 (show IL8 Antibodies) and CCL2 (show CCL2 Antibodies) levels in retinal pigment epithelial cells. Complement factor H (FH) binds mCRP to dampen its proinflammatory activity. FH from AMD (show AMD1 Antibodies) patients carrying the "risk" His402 polymorphism displays impaired binding to mCRP.

  8. The uromodulin (show UMOD Antibodies)-CFH interaction enhanced the cofactor activity of CFH for factor I-mediated cleavage of C3b to inactivated C3b.

  9. Our results revealed that SNPs CD59 (show CD59 Antibodies)-rs831626 and CFH-rs1065489 were associated with the susceptibility of acute anterior uveitis.

  10. Our results show that age-related macular degeneration donors carrying the high risk allele for CFH (C) had significantly more mtDNA damage compared with donors having the wild-type genetic profile.

Pig (Porcine) Complement Factor H (CFH) interaction partners

Complement Factor H (CFH) Antigen Profile

Antigen Summary

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) antibody
  • complement factor H (cfh) antibody
  • complement component factor h (Cfh) antibody
  • complement factor H (Cfh) antibody
  • AHUS1 antibody
  • AMBP1 antibody
  • ARMD4 antibody
  • ARMS1 antibody
  • CFH antibody
  • CFHL3 antibody
  • fH antibody
  • FHL1 antibody
  • HF antibody
  • HF1 antibody
  • HF2 antibody
  • HUS antibody
  • im:7147412 antibody
  • Mud-1 antibody
  • NOM antibody
  • Sas-1 antibody
  • Sas1 antibody
  • si:ch211-207o17.2 antibody

Protein level used designations for CFH

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

GENE ID SPECIES
457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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