anti-Human Complement Factor I antibody for Western Blotting

Recommended Complement Factor I Antibody (supplied by: Log in to see )

Antigen
Complement Factor I (CFI) Antibodies
  • cfi
  • MGC53615
  • Cfi
  • factor I
  • IF
  • gb:ai721528
  • ahus3
  • c3b-ina
  • c3bc4bi
  • c3bina
  • kaf
  • CFI
  • AHUS3
  • C3BINA
  • C3b-INA
  • FI
  • KAF
  • complement factor I
  • Factor I C3b/C4b inactivator (serine protease)
  • complement component factor i
  • complement factor I-like
  • cfi
  • Cfi
  • CFI
  • LOC100516921
Epitope
N-Term
43
7
6
4
3
2
2
1
1
1
1
1
1
1
Reactivity
Human
137
6
6
1
1
1
1
1
1
1
Host
Rabbit
96
39
2
2
Clonality
Polyclonal
Conjugate
This Complement Factor I antibody is un-conjugated
5
5
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
122
59
22
20
15
11
11
10
6
5
4
3
3
2
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Catalog No. ABIN2789418
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.906104 ABIN4299991 IHC WB Mouse IgG2a Log in to see 7C9
2.906104 ABIN1858385 ICC IHC IP WB Rabbit IgG AA 340-583 Log in to see Polyclonal
2.906104 ABIN4299989 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
2.906104 ABIN516816 ELISA WB Mouse IgG2b kappa AA 19-118, partial Log in to see 1B3
2.906104 ABIN516813 WB Mouse AA 1-377, full length Log in to see Polyclonal
2.906104 ABIN516814 WB Mouse AA 1-377, full length Log in to see Polyclonal
2.906104 ABIN516815 WB Rabbit AA 1-377, full length Log in to see Polyclonal
2.906104 ABIN1851162 ELISA WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN315441 FACS IHC (p) IP IHC ELISA WB Mouse IgG1 Log in to see OX-21 1
1 ABIN951648 EIA FACS IP RIA WB FITC Mouse IgG1 Log in to see OX-21 1
1 ABIN4886537 WB Rabbit IgG AA 19-220 Log in to see Polyclonal
1 ABIN181115 EIA Func IHC (fro) WB Mouse IgG1 Log in to see 3R-8 2
1 ABIN951647 EIA FACS IP RIA WB Biotin Mouse IgG1 Log in to see OX-21 4
1 ABIN2487190 EIA FACS IHC (p) IP WB Mouse IgG1 Log in to see OX-21
1 ABIN1451187 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 2
1 ABIN118974 EIA IP RIA WB Mouse IgG1 Log in to see OX-21 1
1 ABIN5514688 WB Rabbit C-Term Log in to see Polyclonal
1 ABIN799400 WB Rabbit AA 145-194 Log in to see Polyclonal
1 ABIN316381 ELISA WB Mouse IgG1 kappa Log in to see 9-00E11
1 ABIN2619180 FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see OX-21

General

Antigen Complement Factor I (CFI) Antibodies
Epitope N-Term
(43), (7), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(137), (6), (6), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(96), (39), (2), (2)
Clonality
Polyclonal
Conjugate This Complement Factor I antibody is un-conjugated
(5), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(122), (59), (22), (20), (15), (11), (11), (10), (6), (5), (4), (3), (3), (2)
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Product Details anti-Complement Factor I Antibody

Target Details Complement Factor I Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN974872
Sequence WSMREANVAC LDLGFQQGAD TQRRFKLSDL SINSTECLHV HCRGLETSLA
Predicted Reactivity Human: 100%
Characteristics This is a rabbit polyclonal antibody against CFI. It was validated on Western Blot.
Purification Affinity Purified

Target Details Complement Factor I

Product Details anti-Complement Factor I Antibody Application Details Handling Images back to top
Antigen
Alternative Name CFI (CFI Antibody Abstract)
Background This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene.
Alias Symbols: AHUS3, C3BINA, C3b-INA, FI, IF, KAF
Protein Interaction Partner: GLP1R, CFH, C3,
Protein Size: 583
Molecular Weight 64 kDa
Gene ID 3426
NCBI Accession NM_000204, NP_000195
UniProt P05156
Pathways Complement System

Application Details

Product Details anti-Complement Factor I Antibody Target Details Complement Factor I Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 583 AA

Restrictions For Research Use only

Handling

Product Details anti-Complement Factor I Antibody Target Details Complement Factor I Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-Complement Factor I Antibody Target Details Complement Factor I Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Complement Factor I (CFI) (N-Term) antibody (ABIN2789418) anti-Complement Factor I (CFI) (N-Term) antibody