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anti-Human CR1 antibody for Immunohistochemistry (Formalin-fixed Sections)

Recommended CR1 Antibody (supplied by: Log in to see )

Antigen
Complement Component Receptor 1 (CD35) (CR1) Antibodies
  • C3BR
  • C3DR
  • C4BR
  • CD21
  • CD35
  • Cr-1
  • Cr-2
  • Cr1
  • KN
Reactivity
Human, Non-Human Primate
193
17
14
10
10
6
4
2
Host
Mouse
167
28
2
Clonality
Monoclonal
Conjugate
This CR1 antibody is un-conjugated
33
30
10
3
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
148
75
59
42
42
37
20
20
11
11
10
4
4
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2749062
$ 231.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00086925825 ABIN2749128 IHC (f) ICC FACS IP IHC (p) WB FITC Mouse IgG1 Log in to see E11 2
0.00086925825 ABIN2749129 IHC (f) ICC FACS IP IHC (p) WB PE Mouse IgG1 Log in to see E11 3
0.00086925825 ABIN2145119 IHC (f) ICC FACS IP IHC (p) WB Mouse IgG1 Log in to see 4AE11
0.00086925825 ABIN2145121 IHC (f) ICC FACS IP IHC (p) WB Mouse IgG1 Log in to see 4AE11
0.00086925825 ABIN2144577 IHC (f) ICC FACS IP IHC (p) WB FITC Mouse IgG1 Log in to see 4AE11
0.00086925825 ABIN2144575 IHC (f) ICC FACS IP IHC (p) WB FITC Mouse IgG1 Log in to see 4AE11
0.00086925825 ABIN2144862 IHC (f) ICC FACS IP IHC (p) WB PE Mouse IgG1 Log in to see 4AE11
0.00086925825 ABIN2144864 IHC (f) ICC FACS IP IHC (p) WB PE Mouse IgG1 Log in to see 4AE11
0.00086925825 ABIN1099623 IHC (f) FACS WB Mouse IgG1 Log in to see To5
0.00086925825 ABIN1099625 IHC (f) FACS WB Biotin Mouse IgG1 Log in to see To5

Top referenced anti-CR1 antibody for Immunohistochemistry (Formalin-fixed Sections)

Similar anti-CR1 Antibodies

Application / Reactivity Non-Human Primate Human
Flow Cytometry (FACS) 5 Antibodies 147 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 21 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 3 Antibodies
ELISA 11 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Functional Studies (Func) 1 Antibodies
Immunoassay (IA) 1 Antibodies
Immunofluorescence (IF) 20 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 43 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 4 Antibodies

General

Antigen Complement Component Receptor 1 (CD35) (CR1) Antibodies
Reactivity Human, Non-Human Primate
(193), (17), (14), (10), (10), (6), (4), (2)
Host Mouse
(167), (28), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CR1 antibody is un-conjugated
(33), (30), (10), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(148), (75), (59), (42), (42), (37), (20), (20), (11), (11), (10), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CR1 Antibody

Target Details CR1 Application Details Handling References for anti-CR1 Antibody (ABIN2749062) Images
Specificity The mouse monoclonal antibody E11 recognizes CD35 (CR1), a type I glycoprotein expressed on granulocytes, monocytes, B cells, folicular dendritic cells, erythrocytes, NK and T cell subsets, as well as e.g. on glomerulal podocytes.
Purification purified.
Immunogen Acute monocytic leukemia cells and normal blood monocytes
Clone E11
Isotype IgG1

Target Details CR1

Product Details anti-CR1 Antibody Application Details Handling References for anti-CR1 Antibody (ABIN2749062) Images back to top
Antigen
Alternative Name CD35 (CR1 Antibody Abstract)
Background CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Complement System

Application Details

Product Details anti-CR1 Antibody Target Details CR1 Handling References for anti-CR1 Antibody (ABIN2749062) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CR1 Antibody Target Details CR1 Application Details References for anti-CR1 Antibody (ABIN2749062) Images back to top
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-CR1 Antibody (ABIN2749062)

Product Details anti-CR1 Antibody Target Details CR1 Application Details Handling Images back to top
Background publications

Kremlitzka, Polgár, Fülöp, Kiss, Poór, Erdei: "Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients." in: International immunology, Vol. 25, Issue 1, pp. 25-33, 2013

Product cited in:

Hogg, Ross, Jones, Slusarenko, Walport, Lachmann: "Identification of an anti-monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1)." in: European journal of immunology, Vol. 14, Issue 3, pp. 236-43, 1984