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|Antigen||Kallikrein 2 (KLK2) Antibodies|
|Conjugate||This Kallikrein 2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|2 references available|
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Product Details anti-Kallikrein 2 AntibodyTarget Details Kallikrein 2 Application Details Handling References for anti-Kallikrein 2 antibody (ABIN358874) Images
|Specificity||This antibody reacts to Kallikrein 2 (KLK2).|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK2.|
Target Details Kallikrein 2Product Details anti-Kallikrein 2 Antibody Application Details Handling References for anti-Kallikrein 2 antibody (ABIN358874) Images back to top
|Alternative Name||KLK2 / Kallikrein-2 (KLK2 Antibody Abstract)|
|Background||Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2, encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.Synonyms: Glandular kallikrein-1, Kallikrein 2, Kallikrein2, Tissue kallikrein-2, hGK-1, hK2|
Application DetailsProduct Details anti-Kallikrein 2 Antibody Target Details Kallikrein 2 Handling References for anti-Kallikrein 2 antibody (ABIN358874) Images back to top
ELISA: 1/1,000. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Kallikrein 2 Antibody Target Details Kallikrein 2 Application Details References for anti-Kallikrein 2 antibody (ABIN358874) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-Kallikrein 2 antibody (ABIN358874)Product Details anti-Kallikrein 2 Antibody Target Details Kallikrein 2 Application Details Handling Images back to top
Haese, Vaisanen, Lilja, Kattan, Rittenhouse, Pettersson, Chan, Huland, Sokoll, Partin et al.: "Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage ..." in: The Journal of urology, Vol. 173, Issue 3, pp. 752-6, 2005
Chiang, Hong, Chang, Chang, Chen: "Human kallikrein-2 gene polymorphism is associated with the occurrence of prostate cancer." in: The Journal of urology, Vol. 173, Issue 2, pp. 429-32, 2005
ImagesProduct Details anti-Kallikrein 2 Antibody Target Details Kallikrein 2 Application Details Handling References for anti-Kallikrein 2 antibody (ABIN358874) back to top