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Browse our Kallikrein 3 Proteins (KLK3)

Full name:
Kallikrein-Related Peptidase 3 Proteins (KLK3)
On www.antibodies-online.com are 3 Kallikrein-Related Peptidase 3 (KLK3) Proteins from 3 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 4 Kallikrein 3 products are currently listed.
Synonyms:
APS, hK3, KLK2A1, KLK3, KLKB1, PSA
list all proteins Gene Name GeneID UniProt
KLK3 354 P07288
KLK3    

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Kallikrein 3 Proteins (KLK3) by Origin

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Human Kallikrein-Related Peptidase 3 (KLK3) interaction partners

  1. Distinctive immunohistochemical expression of PAX8 (show PAX8 Proteins) and lack of prostate-specific antigen can help in distinguishing this benign entity from prostatic adenocarcinoma.

  2. Circulating prostate-derived PSA and membrane PSM mRNA pre- and post-radical prostatectomy improves accuracy of a nomogram to predict biochemical recurrence of prostate cancer.

  3. Purified PSA (show PLAG1 Proteins) cleaves complement factor iC3b in a previously uncharacterized function of PSA (show PLAG1 Proteins) as an immunoregulatory serine protease (show F2 Proteins) that can help create an environment hospitable to malignancy through proteolysis of the complement system.

  4. Extended follow-up of the PLCO trial over a median of 15 years continues to indicate no reduction in prostate cancer mortality for the intervention arm versus the control arm. Because of the high rate of control-arm PSA (show PLAG1 Proteins) testing, this finding can be viewed as showing no benefit of organized screening versus opportunistic screening

  5. Data indicate that prostate specific antigen (PSA) is a negative predictive biomarker for local recurrence during follow-up.

  6. The prostate-specific antigen density (PSAD) cutoff level generated for Nigerian men in this study is 0.04 which is relatively different from international consensus. This PSAD cutoff level has a positive correlation with histology and could detect patients with prostate cancer who have "grey zone PSA (show PLAG1 Proteins)."

  7. In conclusion, serum levels of BSP (show KLK6 Proteins), ALP (show ALP Proteins), ICTP, and PSA (show PLAG1 Proteins) increased in patients with bone metastases, and combined detection of all markers could improve the positive-predictive value.

  8. The combined efficacies of whole-body magnetic resonance imaging, bone scintigraphy and PSA (show PLAG1 Proteins) levels were desired in identifying prostate cancer lesions and prognosis.

  9. A combination of high preoperative serum PSA (show PLAG1 Proteins) and high expression of TMPRSS2 (show TMPRSS2 Proteins)-ERG (show ERG Proteins) could be promising in distinguishing those tumors that are aggressive and life-threatening.

  10. Higher miR (show MLXIP Proteins)-139-5p expression in prostate cancer patients was observed to be associated with certain clinicopathological parameters, including PSA (show PLAG1 Proteins) greater than 20ng/ml, pathological tumor stage, and Gleason score.

Kallikrein 3 (KLK3) Protein Profile

Protein Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Alternative names and synonyms associated with Kallikrein 3 (KLK3)

  • kallikrein-related peptidase 3 (KLK3)
  • kallikrein B, plasma (Fletcher factor) 1 (KLKB1)
  • APS protein
  • hK3 protein
  • KLK2A1 protein
  • KLK3 protein
  • KLKB1 protein
  • PSA protein

Protein level used designations for KLK3

P-30 antigen , gamma-seminoprotein , kallikrein-3 , prostate specific antigen , prostate-specific antigen , semenogelase , seminin , plasma kallikrein B1 , kallikrein-related peptidase 3

GENE ID SPECIES
354 Homo sapiens
100127349 Papio anubis
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