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A combination of high preoperative serum PSA (show PLAG1 Proteins) and high expression of TMPRSS2 (show TMPRSS2 Proteins)-ERG (show ERG Proteins) could be promising in distinguishing those tumors that are aggressive and life-threatening.
Higher miR (show MLXIP Proteins)-139-5p expression in prostate cancer patients was observed to be associated with certain clinicopathological parameters, including PSA (show PLAG1 Proteins) greater than 20ng/ml, pathological tumor stage, and Gleason score.
PSA (show PLAG1 Proteins) velocity can be more predictive after surgery and PSA (show PLAG1 Proteins) doubling time can be more predictive after radiation therapy.
Salvage radiotherapy conferred better prostate cancer control when administered at the very first sign of PSA (show PLAG1 Proteins) rise.
Dynamic changes of ALP (show ALP Proteins), LDH and PSA (show PLAG1 Proteins) during Abiraterone-therapy are associated with best clinical benefit and OS in bone metastatic castration resistant prostate cancer
Studies indicate that the prostate health index (phi) is a biomarker panel that includes free prostate-specific antigen (PSA), total PSA (show PLAG1 Proteins), and [-2]proPSA.
PSCA (show PSCA Proteins) TT genotype is associated with a more than a threefold increase in the prevalence and the extent of gastric mucosal intestinal mucosa compared to C allele carriers among H. pylori-infected Bhutanese.
Prostate magnetic resonance imaging before prostate biopsy appeared to offer similar diagnostic accuracy compared with routine transrectal ultrasound-guided random biopsy in the diagnosis of suspected prostate cancer based on elevated prostate specific antigen values.
We observed an association of higher Ki-67 (show MKI67 Proteins) expression with Gleason sum National Comprehensive Cancer Network risk (P=0.013) and PSA (show PLAG1 Proteins) recurrence
Results show that urinary PSA (show PLAG1 Proteins) glycoforms are able to discriminate prostate cancer from protastatic hyperplasia with higher sensitivity and specificity for prostate cancer than those of the serum PSA (show PLAG1 Proteins) marker.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
, prostate specific antigen
, prostate-specific antigen
, plasma kallikrein B1
, kallikrein-related peptidase 3