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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||9 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||6 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Western Blotting (WB)||52 Antibodies|
|Antigen||Kallikrein 5 (KLK5) Antibodies|
|Epitope||Middle Region Alternatives|
|Conjugate||This Kallikrein 5 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-Kallikrein 5 AntibodyTarget Details Kallikrein 5 Application Details Handling References for anti-Kallikrein 5 Antibody (ABIN358888) Images
|Specificity||This antibody reacts to Kallikrein 5 (KLK5).|
|Purification||Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human KLK5.|
Target Details Kallikrein 5Product Details anti-Kallikrein 5 Antibody Application Details Handling References for anti-Kallikrein 5 Antibody (ABIN358888) Images back to top
|Alternative Name||KLK5 / Kallikrein-5 (KLK5 Antibody Abstract)|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.Synonyms: KLK-5, KLK-L2, Kallikrein-Like Protein 2, SCTE, Stratum corneum tryptic enzyme|
|Gene ID||25818, 9606|
Application DetailsProduct Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Handling References for anti-Kallikrein 5 Antibody (ABIN358888) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Application Details References for anti-Kallikrein 5 Antibody (ABIN358888) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-Kallikrein 5 Antibody (ABIN358888)Product Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Application Details Handling Images back to top
Planque, de Monte, Guyetant et al.: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." in: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, 2005 (PubMed).
Michael, Sotiropoulou, Pampalakis et al.: "Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 14628-35, 2005 (PubMed).
Ishida-Yamamoto, Deraison, Bonnart et al.: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." in: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, 2005 (PubMed).
Brattsand, Stefansson, Lundh et al.: "A proteolytic cascade of kallikreins in the stratum corneum." in: The Journal of investigative dermatology, Vol. 124, Issue 1, pp. 198-203, 2005 (PubMed).
Caubet, Jonca, Brattsand et al.: "Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7." in: The Journal of investigative dermatology, Vol. 122, Issue 5, pp. 1235-44, 2004 (PubMed).
ImagesProduct Details anti-Kallikrein 5 Antibody Target Details Kallikrein 5 Application Details Handling References for anti-Kallikrein 5 Antibody (ABIN358888) back to top