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anti-Dog (Canine) Kallikrein 6 antibody for Immunohistochemistry

Recommended Kallikrein 6 Antibody (supplied by: Log in to see )

Antigen
Kallikrein 6 (KLK6) Antibodies
  • klk6
  • KLK8
  • Klk1b21
  • Klk6
  • rGK-8
  • rk8
  • AI849898
  • BSP
  • Bssp
  • Klk29
  • MSP
  • Prss18
  • Prss9
  • neurosin
  • Klk7
  • PRSS18
  • PRSS9
  • SP59
  • hK6
  • kallikrein 6
  • kallikrein 1-related peptidase C8
  • kallikrein related-peptidase 6
  • kallikrein-related peptidase 6
  • klk6
  • Klk1c8
  • Klk6
  • KLK6
Epitope
N-Term
17
15
9
6
5
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Dog (Canine), Horse (Equine), Human
68
28
28
4
2
Host
Rabbit
65
21
10
Clonality
Polyclonal
Conjugate
This Kallikrein 6 antibody is un-conjugated
7
5
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
68
47
19
13
13
8
6
3
3
2
2
2
1
1
1
1
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Catalog No. ABIN2778179
$ 289.00
Plus shipping costs $45.00

Top referenced anti-Kallikrein 6 antibody for Immunohistochemistry

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General

Antigen Kallikrein 6 (KLK6) Antibodies
Epitope N-Term
(17), (15), (9), (6), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Horse (Equine), Human
(68), (28), (28), (4), (2)
Host Rabbit
(65), (21), (10)
Clonality
Polyclonal
Conjugate This Kallikrein 6 antibody is un-conjugated
(7), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(68), (47), (19), (13), (13), (8), (6), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Kallikrein 6 Antibody

Target Details Kallikrein 6 Application Details Handling References for anti-Kallikrein 6 Antibody (ABIN2778179) Images
Blocking Peptide Blocking peptide for this product available: ABIN979080
Sequence KHNLRQRESS QEQSSVVRAV IHPDYDAASH DQDIMLLRLA RPAKLSELIQ
Predicted Reactivity Dog: 92%, Horse: 92%, Human: 100%
Characteristics This is a rabbit polyclonal antibody against KLK6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human KLK6

Target Details Kallikrein 6

Product Details anti-Kallikrein 6 Antibody Application Details Handling References for anti-Kallikrein 6 Antibody (ABIN2778179) Images back to top
Antigen
Alternative Name KLK6 (KLK6 Antibody Abstract)
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Alias Symbols: Bssp, Klk7, MGC9355, NEUROSIN, PRSS18, PRSS9, SP59, ZYME, hK6
Protein Interaction Partner: SNCA, SERPINF2, SERPINC1,
Protein Size: 244
Molecular Weight 25 kDa
Gene ID 5653
NCBI Accession NM_001012964, NP_001012982
UniProt Q92876
Pathways Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling

Application Details

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Handling References for anti-Kallikrein 6 Antibody (ABIN2778179) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 244 AA

Restrictions For Research Use only

Handling

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Application Details References for anti-Kallikrein 6 Antibody (ABIN2778179) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Kallikrein 6 Antibody (ABIN2778179)

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Application Details Handling Images back to top
Background publications

Li, Hwang, Laxmikanthan, Blaber, Blaber, Golubkov, Ren, Iverson, Georgiou: "Substrate specificity of human kallikreins 1 and 6 determined by phage display." in: Protein science : a publication of the Protein Society, Vol. 17, Issue 4, pp. 664-72, 2008

Images

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Application Details Handling References for anti-Kallikrein 6 Antibody (ABIN2778179) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Kallikrein 6 antibody (KLK6) (N-Term) (ABIN2778179) anti-Kallikrein 6 (KLK6) (N-Term) antibody
Western Blotting (WB) image for anti-Kallikrein 6 antibody (KLK6) (N-Term) (ABIN2778179) Host: Rabbit
Target Name: KLK6
Sample Tissue: Jurkat Whole Cell lysates...