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anti-Mouse (Murine) Kallikrein 6 antibody for Enzyme Immunoassay

Recommended Kallikrein 6 Antibody (supplied by: Log in to see )

Antigen
Kallikrein 6 (KLK6) Antibodies
  • AI849898
  • BSP
  • Bssp
  • hK6
  • Klk1b21
  • klk6
  • Klk6
  • Klk7
  • KLK8
  • Klk29
  • MSP
  • neurosin
  • Prss9
  • PRSS9
  • PRSS18
  • Prss18
  • rGK-8
  • rk8
  • SP59
Epitope
C-Term
18
13
12
6
6
5
5
4
3
3
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Mouse (Murine), Rat (Rattus)
68
26
24
3
2
1
Host
Goat
67
19
9
Clonality
Polyclonal
Conjugate
This Kallikrein 6 antibody is un-conjugated
7
5
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
60
46
17
16
11
8
8
3
2
2
1
1
1
1
1
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Catalog No. ABIN453970
$ 379.50
Plus shipping costs $45.00

Top referenced anti-Kallikrein 6 antibody for Enzyme Immunoassay

Similar anti-Kallikrein 6 Antibodies

Application / Reactivity Cow (Bovine) Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 4 Antibodies 21 Antibodies 12 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 3 Antibodies 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 1 Antibodies 1 Antibodies
ELISA 22 Antibodies

General

Antigen Kallikrein 6 (KLK6) Antibodies
Epitope C-Term
(18), (13), (12), (6), (6), (5), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Cow (Bovine), Mouse (Murine), Rat (Rattus)
(68), (26), (24), (3), (2), (1)
Host Goat
(67), (19), (9)
Clonality
Polyclonal
Conjugate This Kallikrein 6 antibody is un-conjugated
(7), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(60), (46), (17), (16), (11), (8), (8), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-Kallikrein 6 Antibody

Target Details Kallikrein 6 Application Details Handling References for anti-Kallikrein 6 Antibody (ABIN453970) Images
Sequence KEKPGVYTDV CTHIR
Cross-Reactivity (Details) Species reactivity (expected):Rat and Cow.
Species reactivity (tested):Mouse.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen Peptide from the C-Terminus of Mouse Kallikrein-6 according to NP_035307.1.

Target Details Kallikrein 6

Product Details anti-Kallikrein 6 Antibody Application Details Handling References for anti-Kallikrein 6 Antibody (ABIN453970) Images back to top
Antigen
Alternative Name KLK6 / Kallikrein-6 (KLK6 Antibody Abstract)
Background Tissue kallikreins are a family of extracellular serine proteases consisting of 15 members (1, 2). The genes of this family aligned in tandem on chromosome 19q13.4 represent the largest contiguous group of proteases within the human genome. Tissue kallikreins have attracted great interest as potential biomarkers for various cancers, including prostate, ovarian, breast, testicular, and lung (2, 3). Human Kallikrein 6 (hKLK6) is a member of tissue kallikrein family observed in breast and brain tissues, colon carcinoma cells, and oligodedrocytes (1 3). Known protein substrates of hKLK6 are myelin basic protein, the precursor of the Abeta amyloid peptide, and plasminogen. Its physiological functions may include the participation in demyelination processes as well as in the progression of inflammatory disease of the CNS. The level of hKLK6 is reduced in brain extracts of Alzheimer patients and increased in serum of patients with ovarian cancer.Synonyms: Neurosin, PRSS18, PRSS9, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme
Gene ID 5653
NCBI Accession NP_001012982
UniProt Q92876
Pathways Complement System

Application Details

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Handling References for anti-Kallikrein 6 Antibody (ABIN453970) Images back to top
Application Notes Peptide ELISA: Kallikrein-6 Antibody Detection limit dilution 1/16000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Mouse Liver lysates (calculatedMW of 27.2 kDa according to NP_035307.1). An additional band of unknown identity wasalso consistently observed at 42 kDa. Both bands were successfully blocked by incubationwith the immunising peptide.
Restrictions For Research Use only

Handling

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Application Details References for anti-Kallikrein 6 Antibody (ABIN453970) Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-Kallikrein 6 Antibody (ABIN453970)

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Application Details Handling Images back to top
Background publications

Emami, Diamandis: "Human tissue kallikreins: a road under construction." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 381, Issue 1, pp. 78-84, 2007

Paliouras, Borgono, Diamandis: "Human tissue kallikreins: the cancer biomarker family." in: Cancer letters, Vol. 249, Issue 1, pp. 61-79, 2007

Borgoño, Diamandis: "The emerging roles of human tissue kallikreins in cancer." in: Nature reviews. Cancer, Vol. 4, Issue 11, pp. 876-90, 2004

Iwata, Maruyama, Akagi, Hashikawa, Kanazawa, Tsuji, Nukina: "Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2625-35, 2003

Images

Product Details anti-Kallikrein 6 Antibody Target Details Kallikrein 6 Application Details Handling References for anti-Kallikrein 6 Antibody (ABIN453970) back to top
Supplier Images
 image for anti-Kallikrein 6 antibody (KLK6) (C-Term) (ABIN453970) anti-Kallikrein 6 (KLK6) (C-Term) antibody