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|Application / Reactivity||Human|
|Immunocytochemistry (ICC)||2 Antibodies|
|Immunofluorescence (IF)||50 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||34 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||29 Antibodies|
|Luminex Assay (LMNX)||12 Antibodies|
|Western Blotting (WB)||136 Antibodies|
|Antigen||Kallikrein 8 (KLK8) Antibodies|
|Epitope||AA 97-205 Alternatives|
|Conjugate||This Kallikrein 8 antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-Kallikrein 8 AntibodyTarget Details Kallikrein 8 Application Details Handling References for anti-Kallikrein 8 Antibody (ABIN393300) Images
|Specificity||KLK8 (NP_009127, 97 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Purification||This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||KLK8 (NP_009127, 97 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
Target Details Kallikrein 8Product Details anti-Kallikrein 8 Antibody Application Details Handling References for anti-Kallikrein 8 Antibody (ABIN393300) Images back to top
|Alternative Name||KLK8 (KLK8 Antibody Abstract)|
|Background||Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1|
|Molecular Weight||28048 DA|
|Research Area||Cancer, Neurology, Cell Structure|
Application DetailsProduct Details anti-Kallikrein 8 Antibody Target Details Kallikrein 8 Handling References for anti-Kallikrein 8 Antibody (ABIN393300) Images back to top
|Application Notes||Western blot = 1:500-1000|
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Kallikrein 8 Antibody Target Details Kallikrein 8 Application Details References for anti-Kallikrein 8 Antibody (ABIN393300) Images back to top
|Buffer||PBS with 0.09% (w/v) sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
|Storage Comment||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles|
|Expiry Date||6 months|
References for anti-Kallikrein 8 Antibody (ABIN393300)Product Details anti-Kallikrein 8 Antibody Target Details Kallikrein 8 Application Details Handling Images back to top
Klein, Halldén, Cronin et al.: "Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 3, Issue 5, pp. 611-9, 2010 (PubMed).
Planque, Choi, Guyetant et al.: "Alternative splicing variant of kallikrein-related peptidase 8 as an independent predictor of unfavorable prognosis in lung cancer." in: Clinical chemistry, Vol. 56, Issue 6, pp. 987-97, 2010 (PubMed).
Emami, Scorilas, Soosaipillai et al.: "Association between kallikrein-related peptidases (KLKs) and macroscopic indicators of semen analysis: their relation to sperm motility." in: Biological chemistry, Vol. 390, Issue 9, pp. 921-9, 2009 (PubMed).
Brattsand, Stefansson, Hubiche et al.: "SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor." in: The Journal of investigative dermatology, Vol. 129, Issue 7, pp. 1656-65, 2009 (PubMed).
Lu, Huang, Su: "Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory." in: Cell research, Vol. 19, Issue 2, pp. 259-67, 2009 (PubMed).
ImagesProduct Details anti-Kallikrein 8 Antibody Target Details Kallikrein 8 Application Details Handling References for anti-Kallikrein 8 Antibody (ABIN393300) back to top