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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|ELISA||10 Antibodies||9 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies||3 Antibodies|
|Immunocytochemistry (ICC)||2 Antibodies||3 Antibodies|
|Immunofluorescence (IF)||1 Antibodies||3 Antibodies|
|Immunofluorescence (fixed cells) (IF/ICC)||2 Antibodies||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||1 Antibodies||1 Antibodies|
|Immunohistochemistry (IHC)||6 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||2 Antibodies|
|Immunoprecipitation (IP)||2 Antibodies|
|Western Blotting (WB)||15 Antibodies|
|Immunoassay (IA)||2 Antibodies|
|Antigen||Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2) Antibodies|
|Epitope||AA 19-244 Alternatives|
|Reactivity||Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This MBL2 antibody is un-conjugated Alternatives|
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-MBL2 AntibodyTarget Details MBL2 Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for MBL2 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for MBL2 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
Gene Name: mannose-binding lectin (protein C) 2
Protein Name: Mannose-binding protein C
|Purification||Immunogen affinity purified.|
|Immunogen||E. coli-derived rat MBL2 recombinant protein (Position: E19-D244).|
Target Details MBL2Product Details anti-MBL2 Antibody Application Details Handling Images back to top
|Alternative Name||Mbl2 (MBL2 Antibody Abstract)|
MBL2, also called mannose-binding lectin (protein C) 2, soluble or Mannose-binding lectin (MBL) is a lectin that is instrumental in innate immunity. MBL2 is mapped to chromosome 10q11.2-q21. It belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL2 recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding MBL2 to a micro-organism results in activation of the lectin pathway of the complement system. Another important function of MBL2 is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.
Synonyms: Mannose-binding protein C, MBP-C, Mannan-binding protein, Ra-reactive factor polysaccharide-binding component p28A, RaRF p28A, Mbl2
|Pathways||Complement System, Positive Regulation of Immune Effector Process|
Application DetailsProduct Details anti-MBL2 Antibody Target Details MBL2 Handling Images back to top
|Application Notes||Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.|
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
|Restrictions||For Research Use only|
HandlingProduct Details anti-MBL2 Antibody Target Details MBL2 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.