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Mouse (Murine) PLG ELISA Kit for Sandwich ELISA - ABIN820647
Ly, Taylor, Tsatsaronis, Monteleone, Skora, Donald, Maddocks, Nizet, West, Ranson, Walker, McArthur, Sanderson-Smith: Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. in Journal of innate immunity 2014
Human PLG ELISA Kit for Sandwich ELISA - ABIN416924
Wang, Yuan, Zhong, Wen, Deng, Liang, Zheng: The anticoagulant effect of PGI2S and tPA in transgenic umbilical vein endothelial cells is linked to up-regulation of PKA and PKC. in International journal of molecular sciences 2014
VWF (show VWF ELISA Kits) susceptibility to plasmin proteolysis at K1491-R1492 is modulated by local N-linked glycan expression within A1A2A3, and specifically inhibited by heparin binding to the A1 domain.
Plasminogen and P4HA2 (show P4HA2 ELISA Kits) are involved in vascular remodelling and angiogenesis, suggesting a high relevance of these processes for the pathogenic mechanisms underlying this type of vasculitis
Plasminogen and OxPL-PLG were lower in patients presenting with an acute MI than in those with stable CAD (show CAD ELISA Kits) and also in those with atherothrombotic MI (Type 1) vs. those with non-atherothrombotic MI (Type 2).
Although carriers with PLG:p.Ala620Thr show low plasminogen activity, this is not a predisposing variant for aHUS; and individuals of dysplasminogenemia are not at significantly increased risk of aHUS.
Five novel plasminogen gene mutations have been found in Turkish patients with type I plasminogen deficiency.
A novel plasminogen gene mutation, deficiency of plasminogen antigen and activity, and anti-plasminogen IgG and IgA antibodies were identified in a patient with adult-onset ligneous conjunctivitis.
S. aureus NCTC 8325-4 adheres to immobilized plasminogen in vitro and that the adhesion may be mediated by a C-terminal fragment of the PBP3 protein.[PBP3]
we demonstrated that PLG functions as a molecular bridge between tricellulin and streptococcal surface enolase (SEN). The wild type strain efficiently translocated across the epithelial monolayer, accompanied by cleavage of transmembrane junctional proteins.
Suggest that tubulointerstitial plasmin is associated with inflammation leading to renal fibrosis, and can cause the decline in renal function seen in patients with IgA nephropathy.
Plasminogen binding and activation by different glycolytic enzymes of M. pneumoniae play a role in successful colonization of the human respiratory tract.
The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte.
The current study suggests the existence of an active TNF-alpha (show TNF ELISA Kits)-plasminogen-plasmin autocrine/paracrine loop on the massively infiltrated polymorphonuclear neutrophils inside udders of drying-off cows.
examination of interaction with streptococcal plasminogen activator PauA
Plasminogen may regulate DPP-4 (show DPP4 ELISA Kits) activity and glucose metabolism.
Plasminogen-deficient mice frequently develop colon lesions and rectal prolapses.
manganese transport protein (show SLC11A2 ELISA Kits) C (show PROC ELISA Kits) (MntC) is an extracellular matrix- and plasminogen-binding protein (show ENO1 ELISA Kits)
Plg from mouse plasma contains oxPtdPC adducts that are not affected by the action of Lp-PLA(2 (show Lp-PLA2 ELISA Kits)), suggesting that linkage to Plg protects oxPtdPCs from metabolism during their transport in the plasma.
plg-/- and tPA (show PLAT ELISA Kits)-/- mice exhibit brain parenchymal fibrin deposits that appear to result from reduced neurovascular integrity
plasminogen-dependent proteolysis has a beneficial effect during neurological recovery after stroke.
Pla-induced mononuclear cell recruitment in vivo was dependent on protease-activated receptor-1 activation of the MEK/ERK/NF-kappaB pathway, which led to the release of CCL2 and activation of CCR2.
Plg may play an important role in innate immunity by changing expression of genes that contribute to phagocytosis.
Plasminogen is a key molecular determinant of inflammatory joint disease capable of simultaneously driving or ameliorating arthritis pathogenesis in distinct anatomic locations in the same subject.
Plasmin suppresses brain metastasis in two ways: by converting membrane-bound astrocytic FasL (show FASL ELISA Kits) into a paracrine death signal for cancer cells, and by inactivating the axon pathfinding molecule L1CAM (show L1CAM ELISA Kits), which metastatic cells express for spreading along brain capillaries and for metastatic outgrowth.
The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
, lipoprotein, Lp(a)
, plasmin heavy chain A
, plasmin light chain B