Browse our anti-SERPING1 (SERPING1) Antibodies

Full name:
anti-Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 Antibodies (SERPING1)
On www.antibodies-online.com are 177 Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) Antibodies from 25 different suppliers available. Additionally we are shipping SERPING1 Kits (56) and SERPING1 Proteins (35) and many more products for this protein. A total of 277 SERPING1 products are currently listed.
Synonyms:
C1-INH, C1IN, C1INH, C1NH, fb64f02, HAE1, HAE2, im:7159527, LOC100136072, si:dkeyp-110g5.2, wu:fb60c09, wu:fb62a08, wu:fb64f02
list all antibodies Gene Name GeneID UniProt
SERPING1 12258 P97290
SERPING1 710 P05155
SERPING1 295703 Q6P734

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anti-Mouse (Murine) SERPING1 Antibodies:

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anti-Rat (Rattus) SERPING1 Antibodies:

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Top referenced anti-SERPING1 Antibodies

  1. Human Polyclonal SERPING1 Primary Antibody for EIA, WB - ABIN453369 : Park, Ryu, Tosakulwong, Wu, Edwards: Common variation in the SERPING1 gene is not associated with age-related macular degeneration in two independent groups of subjects. in Molecular vision 2009 (PubMed)
    Show all 2 references for 453369

  2. Human Monoclonal SERPING1 Primary Antibody for ELISA - ABIN1997937 : Cicardi, Zingale, Zanichelli, Pappalardo, Cicardi: C1 inhibitor: molecular and clinical aspects. in Springer seminars in immunopathology 2005 (PubMed)

  3. Human Polyclonal SERPING1 Primary Antibody for IHC, ELISA - ABIN1451433 : Bock, Skriver, Nielsen, Thøgersen, Wiman, Donaldson, Eddy, Marrinan, Radziejewska, Huber: Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. in Biochemistry 1986 (PubMed)

  4. Human Polyclonal SERPING1 Primary Antibody for IF, IHC (p) - ABIN390620 : Gösswein, Kocot, Emmert, Kreuz, Martinez-Saguer, Aygören-Pürsün, Rusicke, Bork, Oldenburg, Müller: Mutational spectrum of the C1INH (SERPING1) gene in patients with hereditary angioedema. in Cytogenetic and genome research 2008 (PubMed)

  5. Cow (Bovine) Polyclonal SERPING1 Primary Antibody for IHC (p), IHC - ABIN442446 : Hayashi, Ushizawa, Hosoe, Takahashi: Differential gene expression of serine protease inhibitors in bovine ovarian follicle: possible involvement in follicular growth and atresia. in Reproductive biology and endocrinology : RB&E 2011 (PubMed)

More Antibodies against SERPING1 Interaction Partners

Mouse (Murine) Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) interaction partners

  1. C1INH prevented myocardial ischemia reperfusion injury in mice.

  2. Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor.

  3. Transgenic mice have been generated that express human C1 inhibitor mRNA and protein under the control of the human promoter and regulatory elements; C1nh production is demonstrated in mouse brain, spleen, liver, heart, kidney, and lung.

  4. In vivo, C1 inhibitor (C1INH) reduces the number of viable bacteria in the blood and peritoneal fluid and accelerates killing of bacteria by blood neutrophils and peritoneal macrophages.

  5. C1-inhibitor limits neointimal plaque formation and inflammation. This may involve blockade of complement activation, inhibition of leukocyte recruitment, and reduced triglyceride levels

  6. In addition to the protective activities mediated via inhibition of the complement system, these studies indicate that C1INH also plays a direct role in suppression of leukocyte transmigration into reperfused tissue.

Human Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) interaction partners

  1. findings show that P. falciparum merozoites recruit C1-INH from human serum through an interaction with one of the merozoite surface proteins

  2. PIC1 (show SUMO1 Antibodies) inhibits the peroxidase activity of myeloperoxidase (show MPO Antibodies) in cystic fibrosis (show S100A8 Antibodies) sputum likely via an antioxidant mechanism.

  3. like heparin, polyP is a naturally occurring cofactor for the C1s:C1-INH interaction and thus an important regulator of complement activation

  4. Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is a rare autosomal dominant disease caused by mutations in the C1 inhibitor gene SERPING1. In the present study, the mutational spectrum of the SERPING1 gene in 19 patients of nine unrelated Swiss families were investigated.

  5. Results identified a novel causative mutation in SERPING1, a deletion of two nucleotides on exon 3 in several affected members of two apparently unrelated families with a high frequency of hereditary angioedema.

  6. Study presents the crystal structures of the serpin domain of C1-inhibitor in its active form by itself and in complex with dextran sulfate. The crystal structures and isothermic calorimetry studies show that dextran sulfate binds to multiple C1-inhibitor molecules with low affinity at C1-inhibitor's F1 helix and does not invoke an allosteric change.

  7. Supraphysiological C1-INH concentrations have dose-dependent anticoagulant effects in human whole blood in vitro. At very high levels C1-INH also inhibits fibrinolysis. C1-INH abolished E.coli-induced coagulation measured by thromboelastometry.

  8. This study represents the first Brazilian HAE cohort evaluated for SERPING1 gene mutations and it introduces the possibility to perform genetic analysis in case of need for differential diagnosis.

  9. Suggest that endogenous C1-inhibitor is likely involved in the regulation of complement activity in the myocardium following acute myocardial infarction.

  10. This family-based study provides the first evidence that multiple amino acid substitutions in SERPING1 could influence Hereditary angioedema due to C1-inhibitor deficiency phenotype

SERPING1 Antigen Profile

Antigen Summary

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Alternative names and synonyms associated with SERPING1

  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (serping1) antibody
  • C1 inhibitor (LOC100136072) antibody
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1) antibody
  • serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1) antibody
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (Serping1) antibody
  • C1-INH antibody
  • C1IN antibody
  • C1INH antibody
  • C1NH antibody
  • fb64f02 antibody
  • HAE1 antibody
  • HAE2 antibody
  • im:7159527 antibody
  • LOC100136072 antibody
  • si:dkeyp-110g5.2 antibody
  • wu:fb60c09 antibody
  • wu:fb62a08 antibody
  • wu:fb64f02 antibody

Protein level used designations for SERPING1

C1 inhibitor , fb60c09 , fb62a08 , c1 Inh , plasma protease C1 inhibitor , serine (or cysteine) peptidase inhibitor, clade G, member 1 , serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) , serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 , plasma protease C1 inhibitor-like , C1 Inh , C1 esterase inhibitor , C1-inhibiting factor , complement component 1 inhibitor , serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 , serine (or cysteine) proteinase inhibitor, clade G, member 1 , serpin G1 , serine/cysteine proteinase inhibitor clade G member 1 , C1Inh , serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) , serpin peptidase inhibitor, clade G, member 1 , XIIaINH , complement component 1 inhibitor (angioedema, hereditary) , factor XIIa inhibitor

GENE ID SPECIES
567801 Danio rerio
100136072 Oncorhynchus mykiss
100144304 Sus scrofa
475966 Canis lupus familiaris
703928 Macaca mulatta
100173828 Pongo abelii
100386447 Callithrix jacchus
100583544 Nomascus leucogenys
12258 Mus musculus
710 Homo sapiens
295703 Rattus norvegicus
281035 Bos taurus
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