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Browse our SERPING1 Proteins (SERPING1)

Full name:
Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 Proteins (SERPING1)
On www.antibodies-online.com are 27 Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) Proteins from 11 different suppliers available. Additionally we are shipping SERPING1 Antibodies (80) and SERPING1 Kits (54) and many more products for this protein. A total of 169 SERPING1 products are currently listed.
Synonyms:
C1-INH, C1IN, C1INH, C1NH, fb64f02, HAE1, HAE2, im:7159527, LOC100136072, si:dkeyp-110g5.2, wu:fb60c09, wu:fb62a08, wu:fb64f02
list all proteins Gene Name GeneID UniProt
SERPING1 12258 P97290
SERPING1 710 P05155
SERPING1 295703 Q6P734

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SERPING1 Proteins (SERPING1) by Origin

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Top referenced SERPING1 Proteins

  1. Human SERPING1 Protein expressed in Human Cells - ABIN2003703 : Theriault, Whaley, McPhaden, Boyd, Connor: Regional assignment of the human C1-inhibitor gene to 11q11-q13.1. in Human genetics 1990 (PubMed)
    Show all 2 references for ABIN2003703

  2. Human SERPING1 Protein expressed in Escherichia coli (E. coli) - ABIN1098793 : Davis, Aulak, Zahedi, Bissler, Harrison: C1 inhibitor. in Methods in enzymology 1994 (PubMed)
    Show all 2 references for ABIN1098793

More Proteins for SERPING1 Interaction Partners

Mouse (Murine) Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) interaction partners

  1. C1INH prevented myocardial ischemia reperfusion injury in mice.

  2. Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor.

  3. Transgenic mice have been generated that express human C1 inhibitor mRNA and protein under the control of the human promoter and regulatory elements; C1nh production is demonstrated in mouse brain, spleen, liver, heart, kidney, and lung.

  4. In vivo, C1 inhibitor (C1INH) reduces the number of viable bacteria in the blood and peritoneal fluid and accelerates killing of bacteria by blood neutrophils and peritoneal macrophages.

  5. C1-inhibitor limits neointimal plaque formation and inflammation. This may involve blockade of complement activation, inhibition of leukocyte recruitment, and reduced triglyceride levels

  6. In addition to the protective activities mediated via inhibition of the complement system, these studies indicate that C1INH also plays a direct role in suppression of leukocyte transmigration into reperfused tissue.

Human Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) interaction partners

  1. Suggest that endogenous C1-inhibitor is likely involved in the regulation of complement activity in the myocardium following acute myocardial infarction.

  2. This family-based study provides the first evidence that multiple amino acid substitutions in SERPING1 could influence Hereditary angioedema due to C1-inhibitor deficiency phenotype

  3. the ratio of serum proteoglycan 4 (show PRG4 Proteins) to protease C1 inhibitor may be used for screening of early breast cancer.

  4. Enhancement of C1INH activity was not observed in the refractory septic shock patients, and the C1INH quantitative values were low.

  5. Novel mutations in the SERPING1 gene are linked to Hereditary Angioedema.

  6. Studied human C1INH and found at therapeutically relevant doses, it blocks malaria parasite invasion and cytoadhesion.

  7. SERPING1 mutations in Norwegian patients with Hereditary angioedema with C1 inhibitor deficiency, are reported.

  8. The levels of MASP-1 and MASP-1/C1-INH complexes are reduced in HAE patients compared with controls. Both MASP-1 and MASP-1/C1-INH complexes are related to the degree of complement C4 consumption

  9. SERPING1 is not a major genetic component of AMD (show AMD1 Proteins) or PCV in East Asians but is a genetic risk factor for AMD (show AMD1 Proteins) in Caucasians, providing evidence for an ethnic diversity in the genetic etiology of AMD (show AMD1 Proteins).

  10. C1-inh polymers are present in the plasma of a subgroup of hereditary angioedema type I patients.

SERPING1 Protein Profile

Protein Summary

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Alternative names and synonyms associated with SERPING1

  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (serping1)
  • C1 inhibitor (LOC100136072)
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1)
  • serine (or cysteine) peptidase inhibitor, clade G, member 1 (Serping1)
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (Serping1)
  • C1-INH protein
  • C1IN protein
  • C1INH protein
  • C1NH protein
  • fb64f02 protein
  • HAE1 protein
  • HAE2 protein
  • im:7159527 protein
  • LOC100136072 protein
  • si:dkeyp-110g5.2 protein
  • wu:fb60c09 protein
  • wu:fb62a08 protein
  • wu:fb64f02 protein

Protein level used designations for SERPING1

C1 inhibitor , fb60c09 , fb62a08 , c1 Inh , plasma protease C1 inhibitor , serine (or cysteine) peptidase inhibitor, clade G, member 1 , serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) , serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 , plasma protease C1 inhibitor-like , C1 Inh , C1 esterase inhibitor , C1-inhibiting factor , complement component 1 inhibitor , serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 , serine (or cysteine) proteinase inhibitor, clade G, member 1 , serpin G1 , serine/cysteine proteinase inhibitor clade G member 1 , C1Inh , serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) , serpin peptidase inhibitor, clade G, member 1 , XIIaINH , complement component 1 inhibitor (angioedema, hereditary) , factor XIIa inhibitor

GENE ID SPECIES
567801 Danio rerio
100136072 Oncorhynchus mykiss
100144304 Sus scrofa
475966 Canis lupus familiaris
703928 Macaca mulatta
100173828 Pongo abelii
100386447 Callithrix jacchus
100583544 Nomascus leucogenys
12258 Mus musculus
710 Homo sapiens
295703 Rattus norvegicus
281035 Bos taurus
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