Browse our anti-SSH1 (SSH1) Antibodies

Full name:
anti-Slingshot Homolog 1 (Drosophila) Antibodies (SSH1)
On are 80 Slingshot Homolog 1 (Drosophila) (SSH1) Antibodies from 9 different suppliers available. Additionally we are shipping SSH1 Proteins (5) and SSH1 Kits (1) and many more products for this protein. A total of 89 SSH1 products are currently listed.
AW551225, Gm1394, Gm1395, mSSH-1L, SSH-1, SSH1L
list all antibodies Gene Name GeneID UniProt
Anti-Mouse SSH1 SSH1 231637 Q76I79
SSH1 54434 Q8WYL5

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Top referenced anti-SSH1 Antibodies

  1. Human Polyclonal SSH1 Primary Antibody for WB - ABIN1881835 : Niwa, Nagata-Ohashi, Takeichi, Mizuno, Uemura: Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. in Cell 2002 (PubMed)
    Show all 6 references for 1881835

  2. Fruit Fly (Drosophila melanogaster) Polyclonal SSH1 Primary Antibody for EIA, WB - ABIN492729 : Kligys, Yao, Yu, Jones: 14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 6 references for 492729

  3. Human Polyclonal SSH1 Primary Antibody for IP, WB - ABIN253142 : Guo, Ma, Zhang, Sun, Niu, Ying, Zhang: Pivotal Advance: PKCzeta is required for migration of macrophages. in Journal of leukocyte biology 2009 (PubMed)
    Show all 2 references for 253142

More Antibodies against SSH1 Interaction Partners

Mouse (Murine) Slingshot Homolog 1 (Drosophila) (SSH1) interaction partners

  1. Caspase-11 (show CASP4 Antibodies) targets cofilin (show CFL1 Antibodies) via the RhoA GTPase, whereas caspase-1 (show CASP1 Antibodies) engages the Slingshot phosphatase

  2. SSH1L knockdown, like S1P (show S1PR1 Antibodies) treatment, increased cardiomyocyte survival and preserved mitochondrial integrity after oxidative stress

  3. EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.

  4. PDGF (show PDGFA Antibodies) activates SSH1L in VSMC by a mechanism that involves Nox1 (show NOX1 Antibodies)-mediated oxidation of 14-3-3 (show YWHAQ Antibodies) and Ser (show SIGLEC1 Antibodies)-834 SSH1L auto-dephosphorylation.

  5. Knockdown of SSH1 expression by RNA interference significantly suppressed stress fiber formation in C2C12 myoblast cells, indicating a role for SSH1 in stress fiber formation or stabilization in cells.

Human Slingshot Homolog 1 (Drosophila) (SSH1) interaction partners

  1. SSH1 binds to gelsolin (show GSN Antibodies) via actin filaments in the cytosolic fraction. Gelsolin (show GSN Antibodies) promoted solubilization of actin filaments and SSH1 in cell-free assays and in cultured cells.

  2. the N-terminal PH-like domain plays a critical role in F-actin binding and F-actin-mediated activation of the cofilin (show CFL1 Antibodies)-phosphatase activity of SSH1

  3. Results reveal that SSH1L is upregulated in a subset of PCs and that the SSH1L/cofilin-1 (show CFL1 Antibodies) signal pathway is associated positively in PC with cell migration.

  4. Authors show that viral penetration-induced calcium release facilitated herpes simplex virus type 1 intracellular trafficking through activating slingshot 1 (SSH), a phosphatase regulating actin filament dynamics.

  5. The association of IRS4 (show IRS4 Antibodies) with SSH1 contributes to localized activation of cofilin (show CFL1 Antibodies) in membrane protrusions.

  6. Slingshot 1 downregulation in neuronal cells inactivates cofilin (show CFL1 Antibodies) to facilitate HSV-1 replication.

  7. Thus this study provides evidence for a novel role of LIMK1 (show LIMK1 Antibodies) and SSH-1L in selectively regulating endothelial cell inflammation associated with intravascular coagulation.

  8. Our work provides evidence that supports the positive role of SSH1L in the mechanism of stem cell differentiation into cardiomyocyte-like cells.

  9. A high expression of SSH-1L in peripheral eosinophils in acute exacerbations of asthma may play a role in the activation and migration of eosinophils.

  10. EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.

SSH1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with SSH1

  • slingshot homolog 1 (Drosophila) (Ssh1) antibody
  • slingshot protein phosphatase 1 (SSH1) antibody
  • AW551225 antibody
  • Gm1394 antibody
  • Gm1395 antibody
  • mSSH-1L antibody
  • SSH-1 antibody
  • SSH1L antibody

Protein level used designations for SSH1

SSH-1L , SSH-like protein 1 , protein phosphatase Slingshot homolog 1 , slingshot 1L , slingshot-like 1 , hSSH-1L , slingshot homolog 1

231637 Mus musculus
54434 Homo sapiens
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