Browse our SLC13A5 Proteins (SLC13A5)

Full name:
Solute Carrier Family 13 Member 5 Proteins (SLC13A5)
On www.antibodies-online.com are 3 Solute Carrier Family 13 Member 5 (SLC13A5) Proteins from 2 different suppliers available. Additionally we are shipping SLC13A5 Antibodies (21) and many more products for this protein. A total of 25 SLC13A5 products are currently listed.
Synonyms:
Indy, mINDY, NaC2/NaCT, Nact
list all proteins Gene Name GeneID UniProt
SLC13A5 284111 Q86YT5
SLC13A5 237831 Q67BT3
Rat SLC13A5 SLC13A5 266998 Q8CJ44

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SLC13A5 Proteins (SLC13A5) by Origin

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Human Solute Carrier Family 13 Member 5 (SLC13A5) interaction partners

  1. Data suggest that SLC13A5 plays a role in progression/cell proliferation of human hepatocellular carcinoma cells; here, RNA interference using shRNA against SLC13A5 decreased tumor burden in treatment of hepatocarcinoma in a xenograft tumor model in nude mice.

  2. Data suggest that SLC13A5 plays a role in progression/proliferation of human hepatocellular carcinoma cells; RNA interference using shRNA against SLC13A5 decreased tumor burden in treatment of hepatocarcinoma in a xenograft tumor model in nude mice. [REVIEW]

  3. Study identified additional SLC13A5 mutations in patients with chronic epilepsy starting in the neonatal period, with the mutations producing inactive Na+/citrate transporters.

  4. Studies show that SLC13A5 is a transporter in the plasma membrane that mediates the uptake of citrate into cells. It is expressed in hepatocytes, neurons, and spermatozoa. Its loss-of-function mutations are associated with neonatal epilepsy in humans. This is a single-gene disease with epilepsy resulting solely from the inactivity of SLC13A5. [review]

  5. In infants presenting with therapy resistant seizures in the first days after birth, without a clear history of hypoxic-ischemic encephalopathy, but with Punctate White Matter Lesions on their neonatal MRI (show C7ORF49 Proteins), a diagnosis of SCL13A5 related epileptic encephalopathy should be considered.

  6. Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5).

  7. Eight patients from four families with SLC13A5 mutation are described. They have neonatal epilepsy, tooth hypoplasia, and developmental delay.

  8. SLC13A5 is a novel target gene of PXR (show NR1I2 Proteins) and may contribute to drug-induced steatosis and metabolic disorders in humans.

  9. Screening of 68 additional unrelated individuals with early-onset epileptic encephalopathy for SLC13A5 mutations led to identification of one additional subject with heterozygous mutations of SLC13A5 and a similar clinical presentation as index subjects

  10. This paper describes the cloning and functional characterization of the human Na(+)-coupled citrate transporter (NaCT (show SLC13A2 Proteins)).

Mouse (Murine) Solute Carrier Family 13 Member 5 (SLC13A5) interaction partners

  1. The findings revealed the potentially important role of citrate and Slc13a5 in the development and function of teeth and bone.

  2. Our studies demonstrate a profound effect of mIndy on mammalian energy metabolism.

  3. Molecular cloning and transport properties of NaCT.

  4. Na+ -coupled di/tricarboxylate transport system expressed in neurons as NaC2/NaCT, which can transport the tricarboxylate citrate as well as dicarboxylates such as succinate, alpha-ketoglutarate, and malate.

SLC13A5 Protein Profile

Protein Summary

SLC13A5 is a tricarboxylate plasma transporter with a preference for citrate.

Alternative names and synonyms associated with SLC13A5

  • solute carrier family 13 (sodium-dependent citrate transporter), member 5 (SLC13A5)
  • solute carrier family 13 member 5 (Tsp_08599)
  • solute carrier family 13 (sodium-dependent citrate transporter), member 5 (Slc13a5)
  • Indy protein
  • mINDY protein
  • NaC2/NaCT protein
  • Nact protein

Protein level used designations for SLC13A5

solute carrier family 13 (sodium-dependent citrate transporter), member 5 , solute carrier family 13 member 5 , Na(+)/citrate cotransporter , sodium-coupled citrate transporter , sodium-dependent citrate transporter , solute carrier family 13, member 5 , novel solute carrier family 13 (sodium-dependent dicarboxylate transporter) (Slc13a2 or 3) member

GENE ID SPECIES
417678 Gallus gallus
507000 Bos taurus
606984 Canis lupus familiaris
10907034 Trichinella spiralis
284111 Homo sapiens
237831 Mus musculus
266998 Rattus norvegicus
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