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Cow (Bovine) Polyclonal SLC7A1 Primary Antibody for WB - ABIN2781583
Kaneko, Okuda-Ashitaka, Ando, Nishimura, Igarashi, Maeda, Furuta, Suzuki, Matsumura, Ito: Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells. in American journal of physiology. Cell physiology 2007
Lipopolysaccharide/tumor necrosis factor-alpha (show TNF Antibodies) treatment increased the expression of iNOS (show NOS2 Antibodies), arginase II (show ARG2 Antibodies), CAT-1, and CAT-2 (show SLC7A2 Antibodies) mRNA.
Estradiol increases arginine transport and CAT-1 (show CRAT Antibodies) activity through modulation of constitutive signaling transduction pathways involving ERK (show EPHB2 Antibodies). Progesterone inhibits arginine transport and CAT-1 (show CRAT Antibodies) via both PKCalpha (show PKCa Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) phosphorylation.
The rs41318021 polymorphism in the SLC7A1 gene was not associated with essential hypertension in 50-year-old subjects.
Overexpression of arginine transporter CAT-1 (show CRAT Antibodies) is associated with accumulation of L-arginine (show GATM Antibodies) and cell growth in human colorectal cancer tissue.
CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.
mRNA levels for high-affini (show CRAT Antibodies)ty CAT-1, expressed as a percentage of the wild-type value, are increased by an average 12% an (show DMD Antibodies)d 32% in mdx and transgenic mdx:utr mice respectively.
The data demonstrates that CAT1 (show CRAT Antibodies) significantly (but most likely not exclusively) contributes to the cellular uptake of asymmetric dimethylarginine.
In hypoxic human pulmonary microvascular endothelial cells, overexpression of CAT-1 (show CRAT Antibodies) resulted in significantly greater L-arginine (show GATM Antibodies) transport and NO production
In acute congestive heart failure acute renal impairment function and the modulation of metabolism and extracellular transport by the DDAH-1 (show DDAH1 Antibodies)/CAT-1 (show CRAT Antibodies) system determine high ADMA and SDMA levels after therapy for acute congestive heart failure.
Insulin (show INS Antibodies) increased hCATs-L-arginine (show GATM Antibodies) transport, maximal transport capacity, and hCAT-1 expression. Sp1 (show PSG1 Antibodies) nuclear protein (show RDBP Antibodies) abundance and binding to DNA, and SLC7A1 promoter activity was increased by insulin (show INS Antibodies).
Data show that the CAT-1 (show CRAT Antibodies) isoform plays a role in arginine uptake.
Arginine supplementation enhances small intestinal expression of SLC7A7 (show Slc7a7 Antibodies) and SLC7A1.
Changes in the expression of b(0,+) and CAT-1 in pigs fed on amino acid supplemented versus high proteins diets.
Data show that in minipigs, increased weight and cholesterol resulting from a high-cholesterol diet are correlated with a decrease in the expression of miRNA-122, and that gene expression levels of CAT1 do not differ between groups.
Radiation hybrid mapping data indicate that the porcine SLC7A1 maps to the distal end of the short arm of pig chromosome 11
TRPV6 (show TRPV6 Antibodies)-/- mice spontaneously developed osteoarthritis at a younger age and had more severe manifestations of OA than wild-type controls. TRPV6 (show TRPV6 Antibodies) could regulate certain chondrocyte functions, including ECM (show MMRN1 Antibodies) secretion, cell proliferation, and apoptosis.
A time-dependent decrease in serum and tissue ADMA and increase in mRNA expression of DDAH-1 and PRMT-1 as well as higher rates of mRNA expression of CAT-1 and lower rates of CAT-2A and CAT-2B were found after 8-week MCD diet.
TRPV6 (show TRPV6 Antibodies) plays an essential role in bone metabolism and is a critical regulator in osteoclasts differentiation and bone resorption.
CAT1 overexpression prevents obesity-induced hypertension by reducing the influence of the SNS (show SCN10A Antibodies) on the maintenance of arterial pressure but not by buffering pressor responses to stress.
Adra2a (show ADRA2A Antibodies) is expressed in the mesenchyme of the mouse stomach primordium at E11.5. Fzd5 and Trpv6 (show TRPV6 Antibodies) are expressed in the epithelial layer of the stomach primordium after E11.5.
Endothelial CAT-1 overexpression can counter the ability of oxidative stress.
focus on TRPV6 (show TRPV6 Antibodies) gene polymorphisms, the start of TRPV6 (show TRPV6 Antibodies) translation at a non-AUG codon and the functions of TRPV6 (show TRPV6 Antibodies) in intestinal Ca(2 (show CA2 Antibodies)+) uptake, sperm maturation, and male fertility.
these data indicate that obesity-induced down-regulation of CAT1 expression and subsequent reduced bioavailability of nitric oxide may contribute to the development of obesity-induced hypertension.
Fibroblasts from two long-lived mice mutants (Snell dwarf (show POU1F1 Antibodies) and PAPP-A (show PAPPA Antibodies) knockout) expressed higher levels of CAT1 (a ATF4 (show ATF4 Antibodies) target gene) during stress, suggesting a connection to longevity.
A non-AUG start codon is used in both human and mouse, extending the N-terminus of the protein by 40 amino acids. The increased translation of the smaller TRPV6 (show TRPV6 Antibodies) cDNA version may overestimate the in vivo situation where translation efficiency may represent an additional mechanism to tightly control the TRPV6 (show TRPV6 Antibodies)-mediated Ca(2 (show CA2 Antibodies)+) entry to prevent deleterious Ca(2 (show CA2 Antibodies)+) overload.
acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system
high affinity cationic amino acid transporter 1
, cationic amino acid transporter 1
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
, solute carrier family 7 member 1
, system Y+ basic amino acid transporter
, high affinity cationic amino acid transporter 1-like
, amino acid transporter, cationic 1
, ecotropic retroviral leukemia receptor homolog
, ecotropic retroviral receptor
, ecotropic retrovirus receptor homolog
, cationic amino acid transporter-1
, ecotropic retroviral leukemia receptor
, ecotropic retrovirus receptor
, Solute carrier family 7 member A1 (amino acid transporter cationic 1)
, cationic amino acid transporter, y+ system
, cationinc amino acid transporter 1
, solute carrier family 7, member 1
, calcium transport protein 1
, epithelial calcium channel 2
, osmosensitive transient receptor potential channel 3
, transient receptor potential cation channel subfamily V member 6