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Lipopolysaccharide/tumor necrosis factor-alpha (show TNF ELISA Kits) treatment increased the expression of iNOS (show NOS2 ELISA Kits), arginase II (show ARG2 ELISA Kits), CAT-1, and CAT-2 (show SLC7A2 ELISA Kits) mRNA.
Estradiol increases arginine transport and CAT-1 (show CRAT ELISA Kits) activity through modulation of constitutive signaling transduction pathways involving ERK (show EPHB2 ELISA Kits). Progesterone inhibits arginine transport and CAT-1 (show CRAT ELISA Kits) via both PKCalpha (show PKCa ELISA Kits) and ERK1/2 (show MAPK1/3 ELISA Kits) phosphorylation.
The rs41318021 polymorphism in the SLC7A1 gene was not associated with essential hypertension in 50-year-old subjects.
Overexpression of arginine transporter CAT-1 (show CRAT ELISA Kits) is associated with accumulation of L-arginine (show GATM ELISA Kits) and cell growth in human colorectal cancer tissue.
CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution.
mRNA levels for high-affini (show CRAT ELISA Kits)ty CAT-1, expressed as a percentage of the wild-type value, are increased by an average 12% an (show DMD ELISA Kits)d 32% in mdx and transgenic mdx:utr mice respectively.
The data demonstrates that CAT1 (show CRAT ELISA Kits) significantly (but most likely not exclusively) contributes to the cellular uptake of asymmetric dimethylarginine.
In hypoxic human pulmonary microvascular endothelial cells, overexpression of CAT-1 (show CRAT ELISA Kits) resulted in significantly greater L-arginine (show GATM ELISA Kits) transport and NO production
In acute congestive heart failure acute renal impairment function and the modulation of metabolism and extracellular transport by the DDAH-1 (show DDAH1 ELISA Kits)/CAT-1 (show CRAT ELISA Kits) system determine high ADMA and SDMA levels after therapy for acute congestive heart failure.
Insulin (show INS ELISA Kits) increased hCATs-L-arginine (show GATM ELISA Kits) transport, maximal transport capacity, and hCAT-1 expression. Sp1 (show PSG1 ELISA Kits) nuclear protein (show RDBP ELISA Kits) abundance and binding to DNA, and SLC7A1 promoter activity was increased by insulin (show INS ELISA Kits).
Data show that the CAT-1 (show CRAT ELISA Kits) isoform plays a role in arginine uptake.
Arginine supplementation enhances small intestinal expression of SLC7A7 (show Slc7a7 ELISA Kits) and SLC7A1.
Changes in the expression of b(0,+) and CAT-1 in pigs fed on amino acid supplemented versus high proteins diets.
Data show that in minipigs, increased weight and cholesterol resulting from a high-cholesterol diet are correlated with a decrease in the expression of miRNA-122, and that gene expression levels of CAT1 do not differ between groups.
Radiation hybrid mapping data indicate that the porcine SLC7A1 maps to the distal end of the short arm of pig chromosome 11
Study showed that TRPV6 (show TRPV6 ELISA Kits)-expressing elements seem to be discretely organized in the brain of mouse. TRPV6 (show TRPV6 ELISA Kits)-immunoreactive arcuate neurons co-express estrogen receptor alpha (show ESR1 ELISA Kits) and the ion channel protein (show TRPC3 ELISA Kits) expression in the mediobasal hypothalamus showed correlation with estrous cycle.
TRPV6 (show TRPV6 ELISA Kits)-/- mice spontaneously developed osteoarthritis at a younger age and had more severe manifestations of OA than wild-type controls. TRPV6 (show TRPV6 ELISA Kits) could regulate certain chondrocyte functions, including ECM (show MMRN1 ELISA Kits) secretion, cell proliferation, and apoptosis.
A time-dependent decrease in serum and tissue ADMA and increase in mRNA expression of DDAH-1 and PRMT-1 as well as higher rates of mRNA expression of CAT-1 and lower rates of CAT-2A and CAT-2B were found after 8-week MCD diet.
TRPV6 (show TRPV6 ELISA Kits) plays an essential role in bone metabolism and is a critical regulator in osteoclasts differentiation and bone resorption.
CAT1 overexpression prevents obesity-induced hypertension by reducing the influence of the SNS (show SCN10A ELISA Kits) on the maintenance of arterial pressure but not by buffering pressor responses to stress.
Adra2a (show ADRA2A ELISA Kits) is expressed in the mesenchyme of the mouse stomach primordium at E11.5. Fzd5 and Trpv6 (show TRPV6 ELISA Kits) are expressed in the epithelial layer of the stomach primordium after E11.5.
Endothelial CAT-1 overexpression can counter the ability of oxidative stress.
focus on TRPV6 (show TRPV6 ELISA Kits) gene polymorphisms, the start of TRPV6 (show TRPV6 ELISA Kits) translation at a non-AUG codon and the functions of TRPV6 (show TRPV6 ELISA Kits) in intestinal Ca(2 (show CA2 ELISA Kits)+) uptake, sperm maturation, and male fertility.
these data indicate that obesity-induced down-regulation of CAT1 expression and subsequent reduced bioavailability of nitric oxide may contribute to the development of obesity-induced hypertension.
Fibroblasts from two long-lived mice mutants (Snell dwarf (show POU1F1 ELISA Kits) and PAPP-A (show PAPPA ELISA Kits) knockout) expressed higher levels of CAT1 (a ATF4 (show ATF4 ELISA Kits) target gene) during stress, suggesting a connection to longevity.
acts as a cationic amino acid transporter and as an ecotropic retrovirus receptor\; plays a role in the Na+-independent y+ cationic amino acid transport system
high affinity cationic amino acid transporter 1
, cationic amino acid transporter 1
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
, solute carrier family 7 member 1
, system Y+ basic amino acid transporter
, high affinity cationic amino acid transporter 1-like
, amino acid transporter, cationic 1
, ecotropic retroviral leukemia receptor homolog
, ecotropic retroviral receptor
, ecotropic retrovirus receptor homolog
, cationic amino acid transporter-1
, ecotropic retroviral leukemia receptor
, ecotropic retrovirus receptor
, Solute carrier family 7 member A1 (amino acid transporter cationic 1)
, cationic amino acid transporter, y+ system
, cationinc amino acid transporter 1
, solute carrier family 7, member 1
, calcium transport protein 1
, epithelial calcium channel 2
, osmosensitive transient receptor potential channel 3
, transient receptor potential cation channel subfamily V member 6