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Browse our anti-AlkB, Alkylation Repair Homolog 2 (ALKBH2) Antibodies

Full name:
anti-AlkB, Alkylation Repair Homolog 2 Antibodies (ALKBH2)
On www.antibodies-online.com are 24 AlkB, Alkylation Repair Homolog 2 (ALKBH2) Antibodies from 14 different suppliers available. Additionally we are shipping AlkB, Alkylation Repair Homolog 2 Proteins (11) and many more products for this protein. A total of 39 AlkB, Alkylation Repair Homolog 2 products are currently listed.
Synonyms:
9530023G02, Abh2, AU016977, mABH2, RGD1306377, si:dkey-65b12.2
list all antibodies Gene Name GeneID UniProt
ALKBH2 121642 Q6NS38
ALKBH2 231642 Q6P6J4
ALKBH2 304578  

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Most Popular Reactivities for anti-AlkB, Alkylation Repair Homolog 2 (ALKBH2) Antibodies

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All available anti-AlkB, Alkylation Repair Homolog 2 Antibodies

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Top referenced anti-AlkB, Alkylation Repair Homolog 2 Antibodies

  1. Human Polyclonal ALKBH2 Primary Antibody for EIA, WB - ABIN783675 : Chen, Giri, Zhang, Yamane, Zhang, Maroney, Costa: Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN783675

  2. Cow (Bovine) Polyclonal ALKBH2 Primary Antibody for WB - ABIN2784623 : Yang, Yi, Duguid, Sullivan, Jian, Rice, He: Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. in Nature 2008 (PubMed)

More Antibodies against AlkB, Alkylation Repair Homolog 2 Interaction Partners

Human AlkB, Alkylation Repair Homolog 2 (ALKBH2) interaction partners

  1. studies reveal the ALKBH2 binding interface of PCNA (show PCNA Antibodies) and indicate that both germline and somatic ALKBH2 variants could have cellular effects on ALKBH2 function in DNA repair.

  2. It was shown for first time that DNA glycosylase ALKBH2 can repair DNA adduct 1,N2-ethenoguanine.

  3. ABH2 knockdown impairs rDNA transcription and leads to increased single-stranded and double-stranded DNA breaks in the rDNA genes.

  4. Overexpression of ALKBH2 is associated with enhanced resistance to temozolomide in glioblastoma.

  5. ALKBH2 is an upstream molecule of the oncoprotein, MUC1 (show MUC1 Antibodies), and regulates cell cycle and EMT (show ITK Antibodies), resulting in progression of urothelial carcinomas.

  6. combination of duplex interrogation and oxidation chemistry allows ALKBH2 to detect and process diverse lesions efficiently and correctly

  7. The non-enzymatic binding of AAG (show MPG Antibodies) to 3,N(4)-ethenocytosine specifically blocks ALKBH2-catalyzed repair of 3,N(4)-ethenocytosine but not that of methylated ALKBH2 substrates.

  8. X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2

  9. ABH2 is downregulated in a subset of gastric cancers, and might be involved in the molecular mechanism of gastric cancer through inhibiting the proliferation of gastric cancer cells.

  10. This work has provided a detailed understanding of the structural features of the single-stranded DNA and double-stranded DNA preferences of ABH2 and ABH3 (show ALKBH3 Antibodies).

Mouse (Murine) AlkB, Alkylation Repair Homolog 2 (ALKBH2) interaction partners

  1. ALKBH2 and ALKBH3 (show ALKBH3 Antibodies) provide cancer protection similar to that of the DNA glycosylase AAG (show C16orf35 Antibodies) and display apparent epistasis with Aag (show C16orf35 Antibodies)

  2. Although both Alkbh2 and Alkbh3 (show ALKBH3 Antibodies) can protect against methyl methanesulfonate-induced cell death, only Alkbh2 shows statistically significant protection against mutations following treatment with this exogenous methylating agent.

AlkB, Alkylation Repair Homolog 2 (ALKBH2) Antigen Profile

Antigen Summary

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002

Alternative names and synonyms associated with AlkB, Alkylation Repair Homolog 2 (ALKBH2)

  • alkB, alkylation repair homolog 2 (E. coli) (ALKBH2) antibody
  • alkB, alkylation repair homolog 2 (E. coli) (alkbh2) antibody
  • alkB, alkylation repair homolog 2 (E. coli) (Alkbh2) antibody
  • 9530023G02 antibody
  • Abh2 antibody
  • AU016977 antibody
  • mABH2 antibody
  • RGD1306377 antibody
  • si:dkey-65b12.2 antibody

Protein level used designations for ALKBH2

alkB, alkylation repair homolog 2 (E. coli) , alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 , alpha-ketoglutarate-dependent dioxygenase alkB homolog 2-like , 2OG-Fe(II) oxy DC1 , DNA oxidative demethylase ALKBH2 , alkylated DNA repair protein alkB homolog 2 , oxy DC1 , AlkB homolog 2

GENE ID SPECIES
416897 Gallus gallus
452216 Pan troglodytes
706708 Macaca mulatta
569291 Danio rerio
121642 Homo sapiens
477524 Canis lupus familiaris
511380 Bos taurus
231642 Mus musculus
304578 Rattus norvegicus
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