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anti-Mouse (Murine) CETN2 Antibodies:
anti-Human CETN2 Antibodies:
anti-Rat (Rattus) CETN2 Antibodies:
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Human Polyclonal CETN2 Primary Antibody for IHC, IHC (p) - ABIN4297715
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Human Monoclonal CETN2 Primary Antibody for ELISA, WB - ABIN560340
Barr, Kilmartin, Gergely: CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. in The Journal of cell biology 2010
This study demonistrated that CETN2 regulates protein trafficking of olfactory cilia and participates in specifying planar polarity of ependymal cilia.
Binding of Cen2 and Cen4 to Gbetagamma of non-visual G-proteins regulates G-proteins involved in centrosome and basal body functions
Multidisciplinary approach showed that HsPrp40Ap interacts with centrin (show CETN1 Antibodies) in vitro, supporting a coupled functional role for these proteins in pre-mRNA splicing.
Cetn3 (show CETN3 Antibodies) inhibits Mps1 (show IDUA Antibodies) autophosphorylation at Thr (show TRH Antibodies)-676, a known site of T-loop autoactivation, and interferes with Mps1 (show IDUA Antibodies)-dependent phosphorylation of Cetn2. The cellular overexpression of Cetn3 (show CETN3 Antibodies) attenuates the incorporation of Cetn2 into centrioles and centrosome reduplication, whereas depletion of Cetn3 (show CETN3 Antibodies) generates extra centrioles.
Centrin2 regulates primary ciliogenesis through controlling CP110 (show CCP110 Antibodies) levels.
co-depletion of centrin 2 and PCID2 (show PCID2 Antibodies) leads to blocking rather than delaying nuclear protein (show RDBP Antibodies) export, indicating the dominance of the centrin 2 phenotype.
Data indicate that overexpression of the centrin (show CETN1 Antibodies) interactor POC5 (show POC5 Antibodies) leads to the assembly of linear, centrin (show CETN1 Antibodies)-dependent structures.
CDC25B (show CDC25B Antibodies), through activation of a centrosomal pool of CDK2 (show CDK2 Antibodies), stabilises the local pool of Mps1 (show IDUA Antibodies) which in turn regulates the level of centrin 2 at the centrosome.
Cen2 influences the binding of RPA (show RPA1 Antibodies) and XPA (show XPA Antibodies) with damaged DNA.
xeroderma pigmentosum complementation group C (show XPC Antibodies) expression correlates with a decreased amount of CENTRIN 2 transcript and protein
The stability of centrin (show CETN1 Antibodies) is regulated in part by Aurora A (show AURKA Antibodies).
Mps1 (show IDUA Antibodies)-dependent phosphorylation of Cetn2 stimulates the canonical centriole assembly pathway.
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.
, caltractin, 20 kDa calcium binding protein
, caltractin (20kD calcium-binding protein)