Browse our ERCC1 (ERCC1) ELISA Kits

On www.antibodies-online.com are 22 Excision Repair Cross Complementing Polypeptide-1 (ERCC1) ELISA Kits from 12 different suppliers available. Additionally we are shipping ERCC1 Antibodies (260) and ERCC1 Proteins (11) and many more products for this protein. A total of 304 ERCC1 products are currently listed.
Synonyms:
COFS4, Ercc-1, ercc1, RAD10, T12H1.18, T12H1_18, UV20, UVR7, UV REPAIR DEFICIENT 7
list all ELISA KIts Gene Name GeneID UniProt
ERCC1 2067 P07992
ERCC1 13870 P07903
Rat ERCC1 ERCC1 292673  

ERCC1 (ERCC1) ELISA Kits by Reactivity

More ELISA Kits for ERCC1 Interaction Partners

Arabidopsis thaliana Excision Repair Cross Complementing Polypeptide-1 (ERCC1) interaction partners

  1. ERCC1 and XPF (show ERCC4 ELISA Kits) protect short telomeres from homologous recombination.

Mouse (Murine) Excision Repair Cross Complementing Polypeptide-1 (ERCC1) interaction partners

  1. Dietary tryptophan restriction increased microbial diversity and made the gut (show GUSB ELISA Kits) microbiota composition of old Ercc1(-/Delta7) mice more similar to that of young WT mice.

  2. ERCC1-XPF (show ERCC4 ELISA Kits) cooperates with CTCF (show CTCF ELISA Kits) and cohesin to facilitate the developmental silencing of imprinted genes and that persistent DNA damage triggers chromatin changes that affect gene expression programs associated with NER (show NR1H2 ELISA Kits) disorders.

  3. we quantified the frequency of aneuploidy of three autosomes in the cerebral cortex and cerebellum of adult and developing brain of Bub1b (show BUB1B ELISA Kits)(H/H) mice, which have a faulty mitotic checkpoint (show BUB3 ELISA Kits), and Ercc1(-/Delta7) mice, defective in nucleotide excision repair and inter-strand crosslink repair. we found that Bub1b (show BUB1B ELISA Kits)(H/H), but not Ercc1(-/Delta7) mice, have a significantly higher frequency of aneuploid nuclei relative to wild-t...

  4. these results establish USP45 as a new regulator of XPF (show ERCC4 ELISA Kits)-ERCC1 crucial for efficient DNA repair

  5. ERCC1 is critical for protecting chondrocytes from catabolic stress and is associated with the pathophysiology of osteoarthritis.

  6. SLX4 (show BTBD12 ELISA Kits) is a tumor suppressor, which activates XPF (show ERCC4 ELISA Kits)-ERCC1 nuclease (show DCLRE1C ELISA Kits) specificity in DNA crosslink repair.

  7. ERCC1 is essential for melanoma growth and resistance to cisplatin.

  8. Smad4 (show SMAD4 ELISA Kits) loss-associated Snail (show SNAI1 ELISA Kits) reduction compromises Ercc1-mediated DNA repair, contributing to increased UV-induced skin carcinogenesis.

  9. analysis of accelerated loss of hearing and vision in the DNA-repair deficient Ercc1(delta/-) mouse

  10. This study demonistrated that the ERCC1 deficiency-associated downregulation of the cholesterol biosynthesis pathway is at least in part due to lowered expression of its master transcription factor SREBF2 (show SREBF2 ELISA Kits)

Human Excision Repair Cross Complementing Polypeptide-1 (ERCC1) interaction partners

  1. Genetic polymorphism in ERCC1 gene is associated with response to chemotherapy in osteosarcoma.

  2. ERCC1 was not detectable in the nucleus of the XPF (show ERCC4 ELISA Kits) knockout cells indicating the necessity of a functional XPF (show ERCC4 ELISA Kits)/ERCC1 heterodimer to allow ERCC1 to enter the nucleus.

  3. There is no association between the ERCC1 C19007T polymorphism and platinum-based chemotherapy effectiveness in ovarian cancer. The polymorphism did not have a significant impact on platinum-based chemotherapy in non-responders and responders.

  4. The T allele at ERCC1 rs11615 may interact with smoking and alcohol drinking status to determine personal susceptibility to colorectal cancer.

  5. Strikingly, the addition of the single-stranded DNA (ssDNA)-binding replication protein A (RPA) selectively restores XPF-ERCC1 endonuclease activity on this structure. The 5'-3' exonuclease SNM1A can load from the XPF-ERCC1-RPA-induced incisions and digest past the crosslink to quantitatively complete the unhooking reaction.

  6. ERCC1 mutation along with BRCA1 mutation confers chemoresistance in breast cancer.

  7. The authors have discovered a major sub-pathway of conventional long-patch base excision repair that involves formation of a 9-nucleotide gap 5' to the lesion. This new sub-pathway is mediated by RECQ1 (show RECQL ELISA Kits) DNA helicase and ERCC1-XPF (show ERCC4 ELISA Kits) endonuclease in cooperation with PARP1 poly(ADP-ribose) polymerase (show PARP1 ELISA Kits) and RPA (show RPA1 ELISA Kits).

  8. Based on structural models, NMR titrations, DNA-binding studies, site-directed mutagenesis, charge distribution, and sequence conservation, we propose that the HhH (show SLC25A15 ELISA Kits) domain of ERCC1 binds to dsDNA upstream of the damage, and XPF (show ERCC4 ELISA Kits) binds to the non-damaged strand within a repair bubble

  9. Meta-analysis indicated that the ERCC1 rs3212986 polymorphism and 2 polymorphisms in ERCC2 (show ERCC2 ELISA Kits) gene (rs13181 and rs1799793) contributed to the susceptibility of glioma.

  10. ERCC1-SNP in combination with mRNA ERCC1, DPYD (show DPYD ELISA Kits), and ERBB2 (show ERBB2 ELISA Kits) from pretherapeutic endoscopic biopsies can predict minor response to chemoradiation, as a basis for individualized therapy of advanced esophageal cancer.

ERCC1 Antigen Profile

Antigen Summary

The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.

Alternative names and synonyms associated with ERCC1

  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1) Elisa Kit
  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (Ercc1) Elisa Kit
  • DNA excision repair protein ERCC-1 (CC1G_04546) Elisa Kit
  • DNA excision repair protein ERCC-1 (CpipJ_CPIJ013903) Elisa Kit
  • DNA excision repair protein ERCC-1 (PITG_13719) Elisa Kit
  • DNA excision repair protein ERCC-1 (ercc1) Elisa Kit
  • DNA excision repair protein ERCC-1 (ERCC1) Elisa Kit
  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ercc1) Elisa Kit
  • COFS4 Elisa Kit
  • Ercc-1 Elisa Kit
  • ercc1 Elisa Kit
  • RAD10 Elisa Kit
  • T12H1.18 Elisa Kit
  • T12H1_18 Elisa Kit
  • UV20 Elisa Kit
  • UVR7 Elisa Kit
  • UV REPAIR DEFICIENT 7 Elisa Kit

Protein level used designations for ERCC1

DNA excision repair protein ERCC-1 , excision repair 1 , excision repair cross-complementing 1 , excision repair protein , excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

GENE ID SPECIES
2067 Homo sapiens
13870 Mus musculus
292673 Rattus norvegicus
450179 Pan troglodytes
615637 Bos taurus
6006551 Coprinopsis cinerea okayama7130
6048458 Culex quinquefasciatus
9461287 Phytophthora infestans T30-4
100286713 Salmo salar
819685 Arabidopsis thaliana
380190 Xenopus laevis
574267 Macaca mulatta
612282 Canis lupus familiaris
100135224 Xenopus (Silurana) tropicalis
100286808 Sus scrofa
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