Browse our anti-ERCC2 (ERCC2) Antibodies

Full name:
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 Antibodies (ERCC2)
On www.antibodies-online.com are 63 Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) Antibodies from 17 different suppliers available. Additionally we are shipping ERCC2 Proteins (3) and many more products for this protein. A total of 71 ERCC2 products are currently listed.
Synonyms:
AA407812, AU020867, AW240756, CG9433, COFS2, CXPD, DhR3, DhXPD, Dmel\\CG9433, DmXPD, EM9, Ercc-2, ERCC2, l(2)SH2 2137, l(2)SH2137, MGC89573, TTD, xpd, XPD/ERCC2, zgc:56365
list all antibodies Gene Name GeneID UniProt
ERCC2 100361160  
ERCC2 2068 P18074
ERCC2 13871 O08811

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anti-Mouse (Murine) ERCC2 Antibodies:

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Top referenced anti-ERCC2 Antibodies

  1. Cow (Bovine) Polyclonal ERCC2 Primary Antibody for WB - ABIN2792558 : Braun, Richman, Quirke, Daly, Adlard, Elliott, Barrett, Selby, Meade, Stephens, Parmar, Seymour: Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)

More Antibodies against ERCC2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) interaction partners

  1. XPD expression significantly inhibited HepG2 cell proliferation, promoted HepG2 cell apoptosis, inhibited HepG2 colony formation, decreased HepG2 cells' migratory ability, and significantly lowered HepG2 cells' invasive capacity.

  2. A novel Crb-Galla-Xpd complex and its function for proper chromosome segregation.

  3. The multitask protein Xpd also plays an essential role in cell cycle regulation that appears to be independent of transcription or nucleotide excision repair.

  4. The variant genotypes of XPD Lys751Gln polymorphism are associated with a higher risk of esophageal adenocarcinoma.

Zebrafish Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) interaction partners

  1. the regulation and expression of XPD

  2. The zebrafish cDNA encoding xpd was isolated and examined its spatial-temporal expression during early development as well as its tissue distribution in adult zebrafish.

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) interaction partners

  1. At 24 months of follow-up, patients with xeroderma pigmentosum group D protein (XPD) c.934AA genotype presented lower progression-free survival and overall survival in Kaplan-Meier estimates.

  2. the association of six non-synonymous coding variants from XRCC1 (show XRCC1 Antibodies), XRCC3 (show XRCC3 Antibodies) and XPD genes with hepatocellular carcinoma risk, was assessed.

  3. characterized by a broad spectrum of base changes. In addition, we note an association between the activity of this signature and smoking that is independent of ERCC2 mutation status, providing genomic evidence of tobacco-related mutagenesis in urothelial cancer

  4. Hypermethylation within the promoter region of the ERCC2 gene is associated with gastric cancer.

  5. Meta-analysis indicated that the ERCC1 (show ERCC1 Antibodies) rs3212986 polymorphism and 2 polymorphisms in ERCC2 gene (rs13181 and rs1799793) contributed to the susceptibility of glioma.

  6. significant interactions between ERCC2 (Lys751Gln) and ERCC3 (show ERCC3 Antibodies) (7122 A>G) genotypes polymorphism and cadmium exposure in association with nasal polyposis disease

  7. ERCC2 mutation is associated with sarcoma.

  8. The carriage of homozygous minor allele of DNA repair gene XPD Gln751Gln is a risk factor for thyroid cancer in persons from Ukrainian population exposed to ionizing radiation and is associated with the increased levels of chromosomal instability.

  9. Reduced excision repair cross-complementation group 1 (ERCC1 (show ERCC1 Antibodies)) and group 2 (ERCC2) RNA expressions were detected in 50 (78.1%) and 48 (75%) cases, respectively whereas reduced proteins were detected in 48 cases (75%) for ERCC1 (show ERCC1 Antibodies) and ERCC2.

  10. In conclusion, we provide a useful resource on the mutational landscape of ERCC2 mutations in hereditary BC/OC patients and, as our key finding, we demonstrate the complexity of correct interpretation for the discovery of "bonafide" breast cancer susceptibility genes

Mouse (Murine) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) interaction partners

  1. Results describe a recessive cataract caused by a mutation in the Xpd/Ercc2 gene and demonstrate the importance of the gene not only for lens fiber cell differentiation, but also for the sensitivity to ionizing radiation.

  2. Compound TTD (show GTF2H5 Antibodies)/XPCS heterozygosity partially rescues metabolic phenotype associated with homozygous XPD alleles. TTD (show GTF2H5 Antibodies) allele dominates over XPCS allele in measures of UV-sensitivity.

  3. premature aging associated with XPD mutation in mice

  4. Mutations in XPD subunit of TFIIH (show GTF2H4 Antibodies) result in transactivation defect of PPARs in the adipose tissue and the liver.

  5. New pathology features support the premature aging phenotype of Xpd(TTD) mutant mice and further strengthen the link between DNA damage, DNA repair and aging.

  6. XPCS with a G602D-encoding mutation in the Xpd helicase (show DNA2 Antibodies) gene is the most skin cancer-prone NER (show NR1H2 Antibodies) model to date, and it shows an unusual NER (show NR1H2 Antibodies) dysfunction that is likely responsible for this susceptibility

  7. a variety of biallelic effects on organismal phenotype which attributes to combinations of recessive Xpd alleles

  8. results support a general model for premature aging in Xpd DNA repair deficient mice based on cellular responses to DNA damage that impair normal tissue homeostasis

  9. ERCC2 plays role in lung cancer development in a Chinese population.

ERCC2 Antigen Profile

Antigen Summary

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ERCC2

  • excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2) antibody
  • Xeroderma pigmentosum D (Xpd) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 2 (ercc2) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 2 (LOC100361160) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 2 (Ercc2) antibody
  • AA407812 antibody
  • AU020867 antibody
  • AW240756 antibody
  • CG9433 antibody
  • COFS2 antibody
  • CXPD antibody
  • DhR3 antibody
  • DhXPD antibody
  • Dmel\\CG9433 antibody
  • DmXPD antibody
  • EM9 antibody
  • Ercc-2 antibody
  • ERCC2 antibody
  • l(2)SH2 2137 antibody
  • l(2)SH2137 antibody
  • MGC89573 antibody
  • TTD antibody
  • xpd antibody
  • XPD/ERCC2 antibody
  • zgc:56365 antibody

Protein level used designations for ERCC2

DNA-repair protein complementing XP-D cells , excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) , CG9433-PA , CG9433-PB , CG9433-PC , Xpd-PA , Xpd-PB , Xpd-PC , lethal (2) SH2137 , xeroderma pigmentosum D , TFIIH basal transcription factor complex helicase subunit , XPD , excision repair cross-complementing rodent repair deficiency, complementation group 2 protein , excision repair cross-complementing rodent repair deficiency, complementation group 2 , excision repair cross-complementing 2 , BTF2 p80 , CXPD , DNA excision repair protein ERCC-2 , DNA repair protein complementing XP-D cells , TFIIH 80 kDa subunit , TFIIH basal transcription factor complex 80 kDa subunit , TFIIH basal transcription factor complex helicase XPD subunit , TFIIH p80 , basic transcription factor 2 80 kDa subunit , xeroderma pigmentosum complementary group D , xeroderma pigmentosum group D-complementing protein , excision repair cross-complementing rodent repair deficiency, complementation group 6-like group 2

GENE ID SPECIES
100049685 Sus scrofa
37414 Drosophila melanogaster
393900 Danio rerio
456124 Pan troglodytes
493493 Xenopus (Silurana) tropicalis
493995 Canis lupus familiaris
100361160 Rattus norvegicus
2068 Homo sapiens
100125238 Bos taurus
13871 Mus musculus
308415 Rattus norvegicus
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