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Browse our anti-DNA Repair Protein Complementing XP-G Cells (ERCC5) Antibodies

Full name:
anti-DNA Repair Protein Complementing XP-G Cells Antibodies (ERCC5)
On www.antibodies-online.com are 69 DNA Repair Protein Complementing XP-G Cells (ERCC5) Antibodies from 19 different suppliers available. Additionally we are shipping DNA Repair Protein Complementing XP-G Cells Kits (7) and DNA Repair Protein Complementing XP-G Cells Proteins (5) and many more products for this protein. A total of 87 DNA Repair Protein Complementing XP-G Cells products are currently listed.
Synonyms:
cofs3, ercm2, uvdr, Xpg, xpgc
list all antibodies Gene Name GeneID UniProt
ERCC5 2073 P28715
ERCC5 22592  
ERCC5 301382  

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Top referenced anti-DNA Repair Protein Complementing XP-G Cells Antibodies

  1. Chicken Polyclonal ERCC5 Primary Antibody for WB - ABIN2785634 : Sasaki, Sakano, Okayama, Akao, Hara, Kawai, Ohmi, Hinoda, Naito: DNA repair gene polymorphisms may be associated with prognosis of upper urinary tract transitional cell carcinoma. in Neoplasia (New York, N.Y.) 2008 (PubMed)

  2. Human Polyclonal ERCC5 Primary Antibody for ELISA, WB - ABIN1533685 : Scherly, Nouspikel, Corlet, Ucla, Bairoch, Clarkson: Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2. in Nature 1993 (PubMed)

More Antibodies against DNA Repair Protein Complementing XP-G Cells Interaction Partners

Human DNA Repair Protein Complementing XP-G Cells (ERCC5) interaction partners

  1. Results show that XPG partners with BRCA1 and BRCA2 (show BRCA2 Antibodies) to maintain genomic stability through homologous recombination, and its loss causes DNA breaks, chromosome aberrations, and replication fork stalling.

  2. Helicobacter Pylori introduces double-stranded DNA breaks by the nucleotide excision repair endonucleases XPF (show ERCC4 Antibodies) and XPG, which, together with RelA (show NFkBP65 Antibodies), are recruited to chromatin in a highly coordinated, type IV secretion system-dependent manner.

  3. It has been found that the genotype 751Gln/Gln and allele Gln of ERCC2 (show ERCC2 Antibodies) gene and allele Asp (show ASIP Antibodies) of 312Asn/Asp (show ASIP Antibodies) polymorphism of ERCC2 (show ERCC2 Antibodies) gene may be associated with an increased risk of colorectal cancer.

  4. ERCC5 rs17655 polymorphism might contribute to genetic susceptibility to colorectal cancer.

  5. The results suggest that the XPG-TFIIH (show GTF2H1 Antibodies) complex is involved in transcription elongation and that defects in this association may partly account for Cockayne syndrome in xeroderma pigmentosum group G/Cockayne Syndrome patients.

  6. XRCC1 (show XRCC1 Antibodies) Arg399Gln and XPG His46His might significantly affect the clinical outcomes of platinum-based chemotherapy.

  7. Data show increased risk of leukemia with XPCC (show XPC Antibodies) protein (XPC (show XPC Antibodies)) 939Gln/Gln genotype, ERCC2 (show ERCC2 Antibodies) protein (XPD (show ERCC2 Antibodies)) 751Gln allele may be protective against chronic myeloid leukemia (show BCL11A Antibodies) and acute myeloid leukemia (show BCL11A Antibodies), and no significant risk for the ERCC5 protein (XPG) gene.

  8. our study indicated that ERCC5 rs2094258 polymorphism may contribute to the risk of breast cancer.

  9. XPG Asp1104His polymorphism is a risk factor for head and neck cancer susceptibility.

  10. the rs2296147 and rs2094258 polymorphisms of XPG, could be used as surrogate markers, leading to individualization of non-small cell lung cancer treatment strategies.

Mouse (Murine) DNA Repair Protein Complementing XP-G Cells (ERCC5) interaction partners

  1. HIghlighted in this study is the crucial role of XPG's interactions with TFIIH (show GTF2H4 Antibodies) for proper nucleotide excision repair

  2. XPG gene expression can be influenced by an epigenetic mechanism. Restoration of NER (show NR1H2 Antibodies) activity through XPG gene transfer or treatment with demethylating agents restored sensitivity to nemorubicin.

  3. introduced a point mutation into the XPG gene which inactivates the nuclease (show DCLRE1C Antibodies) catalytic site but leaves the remainder of the protein intact. The mutant mice are hypersensitive to UV irradiation.

  4. Results suggest that the Cockayne syndrome phenotype results from C-terminal truncations in the XPG (xeroderma pigmentosum) gene in mice and humans.

DNA Repair Protein Complementing XP-G Cells (ERCC5) Antigen Profile

Antigen Summary

This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.

Alternative names and synonyms associated with DNA Repair Protein Complementing XP-G Cells (ERCC5)

  • excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 5 (ercc5) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 5 (Ercc5) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) (ERCC5) antibody
  • cofs3 antibody
  • ercm2 antibody
  • uvdr antibody
  • Xpg antibody
  • xpgc antibody

Protein level used designations for ERCC5

DNA repair protein complementing XP-G cells , excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) , DNA excision repair protein ERCC-5 , XPG-complementing protein , xeroderma pigmentosum, complementation group G , DNA repair protein complementing XP-G cells homolog , DNA-repair protein complementing XP-G cells homolog , XP-G related factor , xeroderma pigmentosum group G-complementing protein homolog , XPG

GENE ID SPECIES
100226677 Taeniopygia guttata
2073 Homo sapiens
397963 Xenopus laevis
509602 Bos taurus
22592 Mus musculus
301382 Rattus norvegicus
428019 Gallus gallus
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