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Browse our anti-ERCC6 (ERCC6) Antibodies

Full name:
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 Antibodies (ERCC6)
On www.antibodies-online.com are 83 Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6) Antibodies from 17 different suppliers available. Additionally we are shipping ERCC6 Proteins (3) and many more products for this protein. A total of 91 ERCC6 products are currently listed.
Synonyms:
4732403I04, ARMD5, C130058G22Rik, CKN2, COFS, COFS1, CSB, ercc6, RAD26, UVSS1
list all antibodies Gene Name GeneID UniProt
ERCC6 2074 Q03468
ERCC6 306274  
ERCC6 319955  

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anti-Human ERCC6 Antibodies:

anti-Rat (Rattus) ERCC6 Antibodies:

anti-Mouse (Murine) ERCC6 Antibodies:

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Top referenced anti-ERCC6 Antibodies

  1. Human Polyclonal ERCC6 Primary Antibody for FACS, WB - ABIN654126 : Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007 (PubMed)
    Show all 2 references for ABIN654126

  2. Human Polyclonal ERCC6 Primary Antibody for IHC, ELISA - ABIN1450836 : Troelstra, van Gool, de Wit, Vermeulen, Bootsma, Hoeijmakers: ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. in Cell 1993 (PubMed)
    Show all 2 references for ABIN1450836

  3. Human Polyclonal ERCC6 Primary Antibody for WB - ABIN656032 : Venter, Adams, Myers, Li, Mural, Sutton, Smith, Yandell, Evans, Holt, Gocayne, Amanatides, Ballew, Huson, Wortman, Zhang, Kodira, Zheng, Chen, Skupski, Subramanian, Thomas, Zhang, Gabor Miklos et al.: The sequence of the human genome. ... in Science (New York, N.Y.) 2001 (PubMed)
    Show all 2 references for ABIN656032

More Antibodies against ERCC6 Interaction Partners

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6) interaction partners

  1. The frequency of the XPD (show ERCC2 Antibodies) 312Asn allele was significantly higher in T >/= 2 high grade than in T >/= 2 low grade tumors (p = 0.036); the ERCC6 1097Val/Val genotype was strongly associated with muscle-invasive tumors.

  2. new role of VCP/p97 (show vcp Antibodies) segregase in the timely processing of ubiquitinated CSB from damaged chromatin.

  3. CSB and CTCF (show CTCF Antibodies) can regulate each other's chromatin association, thereby modulating chromatin structure and coordinating gene expression in response to oxidative stress.

  4. Transcription inhibition reduced accumulation of CSB at sites of monoadducts and interstrand crosslinks, but it did not affect recruitment to (although slightly affected retention at) oxidative DNA damage.

  5. Data suggest that both the most C-terminal region and SUMOylation of a lysine residue in N-terminal region are important for functions of CSB/ERCC6 in transcription-coupled nucleotide excision repair following DNA breakage from UV light.

  6. ERCC6 dysfunction presenting as progressive neurological decline with brain hypomyelination. This report expands the disease spectrum associated with ERCC6 mutations.

  7. 33 proteins that were not previously known to interact with CSB.

  8. Data indicate that Cockayne syndrome group B protein CSB function is necessary for the recruitment of recombinational factors.

  9. These studies have provided significant functional and mechanistic insights of Rad26p/CSB in regulation of gene expression and genome integrity as described here.

  10. The present report describes a case of Cockayne syndrome in a Chinese family, with the patients carrying two missense mutations (c.1595A>G, p.Asp532Gly and c.1607T>G, p.Leu536Trp) in the ERCC6 gene in an apparently compound heterozygote.

Mouse (Murine) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6) interaction partners

  1. Our data show that in addition to promoting repeat expansion, CSB does in fact protect the genome from germ line expansions in the FXD mouse model.

  2. loss of CSB affects tandem-repeat expansions in a gender and cell-type-specific manner

  3. CSB has been shown to regulate processes such as the transcriptional recovery after DNA damage, the p53 (show TP53 Antibodies) transcriptional response, the response to hypoxia, the response IGF-1 (show IGF1 Antibodies), transactivation of nuclear receptors, transcription of housekeeping genes

  4. CSB and PCAF (show KAT2B Antibodies) play cooperative roles to establish the active state of rRNA genes by histone acetylation

  5. Csb-/- neural precursors exhibited defective self-renewal in the neurosphere assay.

  6. Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a cs-b xp-c murine model of Cockayne syndrome

  7. Testicular nuclear receptor 4 (TR4 (show NR2C2 Antibodies)) regulates UV light-induced responses via Cockayne syndrome B protein-mediated transcription-coupled DNA repair

  8. Data suggest that Cockayne syndrome B protein protects CAG repeats from expansion by either active reduction of the tract length during parent-child transmission, or by antagonizing the action of OGG1 (show OGG1 Antibodies), which tends to promote expansion in somatic cells.

  9. These results suggested that reduced repair of a DNA topoisomerase I-DNA covalent complex because of truncated CSB proteins is involved in the pathogenesis of CS-B.

  10. MtDNA mutations are highly increased in cells from subcutaneous fat of aged Csb(m/m) mice

ERCC6 Antigen Profile

Antigen Summary

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544.

Alternative names and synonyms associated with ERCC6

  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (Ercc6) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (ercc6) antibody
  • 4732403I04 antibody
  • ARMD5 antibody
  • C130058G22Rik antibody
  • CKN2 antibody
  • COFS antibody
  • COFS1 antibody
  • CSB antibody
  • ercc6 antibody
  • RAD26 antibody
  • UVSS1 antibody

Protein level used designations for ERCC6

ATP-dependent helicase ERCC6 , Cockayne syndrome group B protein , DNA excision repair protein ERCC-6 , cockayne syndrome protein CSB , CS group B correcting , excision repair cross-complementing rodent repair deficiency, complementation group 6

GENE ID SPECIES
2074 Homo sapiens
306274 Rattus norvegicus
319955 Mus musculus
548810 Xenopus (Silurana) tropicalis
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