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Browse our ERCC8 Proteins (ERCC8)

Full name:
Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 Proteins (ERCC8)
On www.antibodies-online.com are 6 Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) Proteins from 4 different suppliers available. Additionally we are shipping ERCC8 Antibodies (88) and many more products for this protein. A total of 106 ERCC8 products are currently listed.
Synonyms:
2410022P04Rik, 2810431L23Rik, 4631412O06Rik, B130065P18Rik, Ckn1, Csa, UVSS2, zgc:103550
list all proteins Gene Name GeneID UniProt
ERCC8 1161 Q13216
Rat ERCC8 ERCC8 310071  
ERCC8 71991 Q8CFD5

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ERCC8 Proteins (ERCC8) by Origin

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More Proteins for ERCC8 Interaction Partners

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) interaction partners

  1. Although the absence of CSA had no effect on CSB recruitment, CSA itself localized at sites of interstrand crosslinks, double-strand breaks and monoadducts but not at oxidative DNA lesions.

  2. Our findings suggested that ERCC8 rs158572 and rs158916, alone or together with environmental factors, might be associated with gastric cancer and atrophic gastritis susceptibility.

  3. A novel function of Cockayne syndrome A protein as transcription factor of RNA polymerase I (show POLR1C Proteins) in the nucleolus is shown.

  4. Mitochondrial CSA and CSB: protein interactions and protection from ageing associated DNA mutations.

  5. The role of CSA and CSB protein in the oxidative stress response.

  6. The role of CSA protein in TC-NER (show NR1H2 Proteins) is described in this review

  7. The review focuses on the participation of the CSB and CSA proteins in many different protein interactions and complexes, and how these interactions inform us about pathways that are defective in the disease.

  8. KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR).

  9. CSA and CSB (show ERCC6 Proteins) are identified as the key elements of a regulatory mechanism that equilibrate beneficial and detrimental effects of p53 (show TP53 Proteins) activity upon cellular stress.

  10. crystals of CSA-DDB1 (show DDB1 Proteins) had unit-cell parameters a = b = 142.03, c = 250.19 A and diffracted to 2.9 A resolution on beamline ID14-1

Mouse (Murine) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) interaction partners

  1. MtDNA mutations are highly increased in cells from subcutaneous fat of aged Csa(-/-) mice

  2. difference in oxidative DNA damage sensitivity between CSA- and CSB-deficient cell lines and mice

ERCC8 Protein Profile

Protein Summary

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Alternative names and synonyms associated with ERCC8

  • excision repair cross-complementing rodent repair deficiency, complementation group 8 (ercc8)
  • excision repair cross-complementing rodent repair deficiency, complementation group 8 (ERCC8)
  • excision repair cross-complementing rodent repair deficiency, complementation group 8 (Ercc8)
  • excision repaiross-complementing rodent repair deficiency, complementation group 8 (Ercc8)
  • 2410022P04Rik protein
  • 2810431L23Rik protein
  • 4631412O06Rik protein
  • B130065P18Rik protein
  • Ckn1 protein
  • Csa protein
  • UVSS2 protein
  • zgc:103550 protein

Protein level used designations for ERCC8

DNA excision repair protein ERCC-8 , Cockayne syndrome 1 protein , Cockayne syndrome WD-repeat protein CSA , cockayne syndrome WD repeat protein CSA , Cockayne syndrome 1 (classical) , excision repaiross-complementing rodent repair deficiency, complementation group 8 , Cockayne syndrome 1 homolog , cockayne syndrome WD repeat protein CSA homolog

GENE ID SPECIES
449811 Danio rerio
427153 Gallus gallus
1161 Homo sapiens
487225 Canis lupus familiaris
518857 Bos taurus
310071 Rattus norvegicus
71991 Mus musculus
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