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Browse our MCM3 Proteins (MCM3)

Full name:
Minichromosome Maintenance Complex Component 3 Proteins (MCM3)
On are 4 Minichromosome Maintenance Complex Component 3 (MCM3) Proteins from 3 different suppliers available. Additionally we are shipping MCM3 Antibodies (93) and MCM3 Kits (2) and many more products for this protein. A total of 104 MCM3 products are currently listed.
AL033361, C80350, cb32, CG4206, chunp6867, dMCM3, Dmel\\CG4206, DmeMCM3, DmMcm3, HCC5, McM3, Mcmd, Mcp-PCR2, P1, P1-MCM3, P1.h, p1.m, PCR2, RLFB, wu:fa26g03, xmcm3
list all proteins Gene Name GeneID UniProt
MCM3 4172 P25205
Rat MCM3 MCM3 316273  
MCM3 17215 P25206

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MCM3 Proteins (MCM3) by Origin

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Top referenced MCM3 Proteins

  1. Human MCM3 Protein expressed in Wheat germ - ABIN1310549 : Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia. in Journal of immunological methods 2011 (PubMed)

More Proteins for MCM3 Interaction Partners

Human Minichromosome Maintenance Complex Component 3 (MCM3) interaction partners

  1. High MCM-3 expression correlated with Cutaneous T-cell Lymphomas.

  2. normal DNA replication and replication checkpoint activation is regulated through the novel phosphorylation of MCM3 by Chk1 (show CHEK1 Proteins)

  3. Results show that in Glioma patients, MCM 2 (show MCM2 Proteins), MCM3 and MCM7 (show MCM7 Proteins) mRNA are up-regulated and correlated with poor outcome.

  4. Of the total, the deregulation of several genes (CDK1 (show CDK1 Proteins), CDK2 (show CDK2 Proteins), CDK4 (show CDK4 Proteins), MCM2 (show MCM2 Proteins), MCM3, MCM4 (show MCM4 Proteins), EIF3a (show EIF6 Proteins) and RPN2 (show PSMD1 Proteins)) were potentially associated with disease development and progression.

  5. Relatively lower MCM3 protein expression in follicular variant of papillary thyroid carcinoma comparing to classical type could be due to a different tumorigenic pathway favored in this type of tissue.

  6. Expression of KB cell MCM3 was not affected by doxorubicin.

  7. present study aimed to investigate the relationship between expression of minichromosome maintenance proteins (MCM-3, MCM-7 (show MCM7 Proteins)), metallothioneins (MT-I (show MT1 Proteins)/II, MT-III (show MT3 Proteins)), and Ki-67 (show MKI67 Proteins) in 103 ovarian cancer cases, mostly of the serous histological type

  8. Mcm2-7 (show MCM2 Proteins) loads onto origins during initiation as a double hexamer, yet does not act as a double-stranded DNA pump during elongation.

  9. High MCM3 expression is associated with mucoepidermoid carcinomas and adenoid cystic carcinomas in salivary gland tumors.

  10. These findings provide validation of the utility of MCM3 expression as an independent biomarker for prognostication of patients with primary melanoma

Mouse (Murine) Minichromosome Maintenance Complex Component 3 (MCM3) interaction partners

  1. Mcm3-deficient erythroblasts display aberrant DNA replication patterns and fail to complete maturation, causing lethal anemia.

  2. interaction with GANP (show MCM3AP Proteins) DNA-primase is associated with a novel phosphatase component G5PR (show PPP2R3C Proteins)

  3. Depletion of Orc2 and Mcm3 by siRNA leads to an inhibition of cell proliferation, an altered cell cycle distribution as well as to multinucleated cells with insufficiently organised microtubules.

  4. analysis of carboxyl-terminal MCM3 phosphorylation sites and their motifs

  5. These data reveal that CDK (show CDK4 Proteins)-dependent MCM3 phosphorylation contributes to the regulated formation of the MCM2-7 (show MCM2 Proteins) complex.

MCM3 Protein Profile

Protein Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MCM3

  • Minichromosome maintenance 3 (Mcm3)
  • minichromosome maintenance complex component 3 (MCM3)
  • zygotic DNA replication licensing factor mcm3 (zmcm3)
  • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) (mcm3)
  • minichromosome maintenance complex component 3 (mcm3)
  • minichromosome maintenance complex component 3 (Mcm3)
  • minichromosome maintenance deficient 3 (S. cerevisiae) (Mcm3)
  • AL033361 protein
  • C80350 protein
  • cb32 protein
  • CG4206 protein
  • chunp6867 protein
  • dMCM3 protein
  • Dmel\\CG4206 protein
  • DmeMCM3 protein
  • DmMcm3 protein
  • HCC5 protein
  • McM3 protein
  • Mcmd protein
  • Mcp-PCR2 protein
  • P1 protein
  • P1-MCM3 protein
  • P1.h protein
  • p1.m protein
  • PCR2 protein
  • RLFB protein
  • wu:fa26g03 protein
  • xmcm3 protein

Protein level used designations for MCM3

CG4206-PA , Mcm3-PA , minichromosome maintenance 3 , minichromosome maintenance-PCR2 , MCM3 minichromosome maintenance deficient 3 , zygotic minichromosome maintenance protein 3 , DNA replication licensing factor MCM3 , DNA polymerase alpha holoenzyme-associated protein P1 , DNA replication factor MCM3 , RLF subunit beta , cervical cancer proto-oncogene 5 , hRlf beta subunit , minichromosome maintenance deficient 3 , p102 , replication licensing factor, beta subunit , P1 homolog , XRLF subunit beta , mMCM3 , maternal DNA replication licensing factor mcm3 , maternal minichromosome maintenance protein 3 , p100 , P1-MCM3 , mini chromosome maintenance deficient

31449 Drosophila melanogaster
100069108 Equus caballus
734092 Xenopus (Silurana) tropicalis
192323 Danio rerio
4172 Homo sapiens
397821 Xenopus laevis
422043 Gallus gallus
281302 Bos taurus
316273 Rattus norvegicus
481839 Canis lupus familiaris
100154824 Sus scrofa
17215 Mus musculus
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