anti-Mouse (Murine) Minichromosome Maintenance Complex Component 6 antibody for Immunohistochemistry

Recommended Minichromosome Maintenance Complex Component 6 Antibody (supplied by: Log in to see )

Antigen
Minichromosome Maintenance Complex Component 6 (MCM6) Antibodies
  • CG4039
  • DmMCM6
  • DmeMCM6
  • Dmel\\CG4039
  • MCM6
  • McM6
  • fs(1)K1214
  • mcm6
  • MCG40308
  • Mis5
  • P105MCM
  • Mcmd6
  • mis5
  • mmcm6
  • ASP-l1
  • D1Wsu22e
  • Minichromosome maintenance 6
  • DNA replication licensing factor MCM6
  • minichromosome maintenance complex component 6
  • minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
  • Protein MCM-6
  • Mcm6
  • TP02_0113
  • PVX_114735
  • CMU_027970
  • MCM6
  • mcm6
  • mcm-6
Epitope
C-Term
16
15
11
6
5
4
3
3
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
89
32
20
16
11
11
9
7
4
2
1
1
1
1
Host
Rabbit
80
7
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
83
45
29
27
17
6
5
3
2
2
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2774885
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.869446 ABIN2774886 IHC WB Rabbit C-Term Log in to see Polyclonal 1
8.869446 ABIN3022687 IHC WB Rabbit IgG Log in to see Polyclonal 3
8.869446 ABIN3198195 IC IF IHC WB Rabbit Log in to see Polyclonal
8.869446 ABIN1873666 IF IHC WB Rabbit IgG Log in to see Polyclonal
8.869446 ABIN2470083 IHC WB Rabbit IgG Log in to see Polyclonal
8.869446 ABIN2404854 IF IHC WB Rabbit IgG Log in to see Polyclonal
8.869446 ABIN2428397 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
8.869446 ABIN2421837 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN151757 ICC IF IHC IHC (p) PLA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN4333212 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 2
1 ABIN328345 IHC Rabbit C-Term Log in to see Polyclonal
1 ABIN2880003 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1088680 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1088679 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2894462 IHC WB Rabbit Log in to see Polyclonal
1 ABIN2311663 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2973090 IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal

General

Antigen Minichromosome Maintenance Complex Component 6 (MCM6) Antibodies
Epitope C-Term
(16), (15), (11), (6), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(89), (32), (20), (16), (11), (11), (9), (7), (4), (2), (1), (1), (1), (1)
Host Rabbit
(80), (7), (4)
Clonality
Polyclonal
Conjugate Un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(83), (45), (29), (27), (17), (6), (5), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product details

Target details Application Details Handling References Images
Blocking Peptide Blocking peptide for this product available: ABIN979901
Sequence RIIEKVIHRL THYDHVLIEL TQAGLKGSTE GSESYEEDPY LVVNPNYLLE
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against MCM6. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human MCM6

Target details

Product details Application Details Handling References Images back to top
Antigen
Alternative Name MCM6 (MCM6 Antibody Abstract)
Background The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Alias Symbols: MCG40308, Mis5, P105MCM
Protein Interaction Partner: MCM10, HUWE1, SNRPB2, MCM2, NUDT2, ZBTB9, FAM161A, UBC, SUMO2, SUMO3, MCMBP, POLK, MCM4, MCM3, KPNA3, HSP90AB1, CDKN2A, ACLY, CAP1, ING5, MCM6, BAG3, TONSL, MMS22L, ASF1B, SMC1A, MCM7, CCNA1, VCAM1, ITGA4, FN1, gag-pol, GMNN, ORC6, DBF4, CDC7, PAXIP1, TP5
Protein Size: 821
Molecular Weight 90 kDa
Gene ID 4175
NCBI Accession NM_005915, NP_005906
UniProt Q14566
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Pathways DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA

Application Details

Product details Target details Handling References Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 821 AA

Restrictions For Research Use only

Handling

Product details Target details Application Details References Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Product details Target details Application Details Handling Images back to top
Product cited in:

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, 2006

Background publications

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006

Images

Product details Target details Application Details Handling References back to top
Supplier Images
Western Blotting (WB) image for anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibody (ABIN2774885) WB Suggested Anti-MCM6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Immunohistochemistry (IHC) image for anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibody (ABIN2774885) Immunohistochemistry with Thymus tissue at an antibody concentration of 5µg/ml using ...
Immunohistochemistry (IHC) image for anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibody (ABIN2774885) Thymus