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Browse our anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Antibodies

Full name:
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) Antibodies (MRE11A)
On www.antibodies-online.com are 168 MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Antibodies from 26 different suppliers available. Additionally we are shipping MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) Proteins (6) and MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) Kits (4) and many more products for this protein. A total of 187 MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) products are currently listed.
Synonyms:
ATLD, HNGS1, MRE11, MRE11B, wu:faa63d12, zgc:64018
list all antibodies Gene Name GeneID UniProt
MRE11A 17535 Q61216
MRE11A 4361 P49959
MRE11A 64046 Q9JIM0

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Top referenced anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) Antibodies

  1. Dog (Canine) Polyclonal MRE11A Primary Antibody for EIA, WB - ABIN401319 : Zhang, Paull: The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S. cerevisiae. in DNA repair 2005 (PubMed)
    Show all 4 references for ABIN401319

  2. Human Monoclonal MRE11A Primary Antibody for IF, WB - ABIN968498 : Haber: The many interfaces of Mre11. in Cell 1998 (PubMed)
    Show all 3 references for ABIN968498

  3. Yeast (Saccharomyces cerevisiae) Polyclonal MRE11A Primary Antibody for ChIP, EIA - ABIN401304 : Johzuka, Ogawa: Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. in Genetics 1995 (PubMed)
    Show all 2 references for ABIN401304

  4. Human Polyclonal MRE11A Primary Antibody for ELISA, WB - ABIN1532773 : Petrini, Walsh, DiMare, Chen, Korenberg, Weaver: Isolation and characterization of the human MRE11 homologue. in Genomics 1996 (PubMed)

  5. Human Polyclonal MRE11A Primary Antibody for EIA, IF - ABIN500290 : Buis, Wu, Deng, Leddon, Westfield, Eckersdorff, Sekiguchi, Chang, Ferguson: Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. in Cell 2008 (PubMed)

  6. Human Polyclonal MRE11A Primary Antibody for IF (p), IHC (p) - ABIN747293 : Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. in International journal of nanomedicine 2014 (PubMed)

More Antibodies against MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) Interaction Partners

Mouse (Murine) MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) interaction partners

  1. The authors demonstrate that ATM (show ATM Antibodies) can be activated by DNA double-strand breaks in the absence of the Mre11-Rad50 (show RAD50 Antibodies)-NBS1 (show NBN Antibodies) (MRN) sensor complex.

  2. TRIP13 (show TRIP13 Antibodies)-deficient spermatocytes also progress to an H1t (show HIST1H1T Antibodies)-positive stage if ATM (show ATM Antibodies) activity is attenuated by hypomorphic mutations in Mre11 or Nbs1 (show NBN Antibodies) or by elimination of the ATM (show ATM Antibodies)-effector kinase CHK2 (show CHEK2 Antibodies)

  3. Impairment of Mre11 complex functions promotes the progression of mammary hyperplasias into invasive and metastatic breast cancers

  4. results suggest that the MRE11-RAD50 (show RAD50 Antibodies) complex plays important roles in recognition of dsDNA and initiation of STING-dependent signaling, in addition to its role in DNA-damage responses

  5. The critical role of the MRE11 GAR motif in DSB repair is a mechanistic link between post-translational modifications at the MRE11 GAR motif and DSB processing, as well as the ATR (show ATR Antibodies)/CHK1 (show CHEK1 Antibodies) checkpoint signaling.

  6. Mre11 is present in mitochondria where it binds to mtDNA and that the amount in mitochondria varies depending on cellular stress and differentiation.

  7. Data show that CS-mediated SCC (show CYP11A1 Antibodies) lethality was mitigated in irradiated gain-of-function Rad50 (show RAD50 Antibodies)(s/s) mice, and epistasis studies order Rad50 (show RAD50 Antibodies) upstream of Mre11.

  8. MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.

  9. The data indicate that even subtle perturbation of Mre11 complex functions results in severe genotoxic stress, and that the complex is critically important for homeostasis of proliferative tissues.

  10. following high NaCl, Mre11 exits from the nucleus, DNA double-strand breaks accumulate in the S and G2 phases of the cell cycle, and DNA repair is inhibited.

Human MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) interaction partners

  1. The expression of DSB repair proteins such as RAD51 (show RAD51 Antibodies) and MRE11 was investigated by immunohistochemistry, and associations between RAD51 (show RAD51 Antibodies) and MRE11 expression and clinicopathological factors or chemotherapeutic effect were assessed

  2. The MRN complex is essential to restrain MYCN (show MYCN Antibodies)-induced replication stress during neural cell proliferation.

  3. This study found a significant trend indicating that the risk increases as the number of adverse alleles increase and significant three-locus interaction model involving NBS1 (show NBN Antibodies) rs1805794, MRE11 rs10831234, and ATM (show ATM Antibodies) rs227062.

  4. a significant increase in DKC1, RAD50, MRE11 and RPA1 expression in MM cases with high bone marrow infiltration (pISS stage

  5. Rad51 (show RAD51 Antibodies) recombinase (show RAG1 Antibodies) prevents Mre11 nuclease (show DCLRE1C Antibodies)-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation

  6. The importance of the FGFR2 (show FGFR2 Antibodies)-Mre11-DSBR link in cancer progression is suggested by the finding that genotypes of FGFR2 (show FGFR2 Antibodies) and Mre11 are associated with survival of breast cancer patients

  7. Loss of the MRE11 protein predicts sensitivity to PARP (show COL11A2 Antibodies)-inhibitor sensitivity in vitro, defining it as an additional synthetic lethal gene with PARP (show COL11A2 Antibodies).

  8. This work demonstrates that the Mre11-Rad50 (show RAD50 Antibodies)-Nbs1 (show NBN Antibodies) DNA repair complex positively regulates AAV replication and plays a role in the integration of adeno (show ADORA2A Antibodies)-associated airus in the presence of herpes simplex virus 1.

  9. ATP switches the Mre11-Rad50 (show RAD50 Antibodies)-Nbs1 (show NBN Antibodies) repair factor between signaling and processing of DNA ends. (Review)

  10. Low expression of MRE11 was associated with serous ovarian cancer.

MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Antigen Profile

Antigen Summary

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog\; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Alternative names and synonyms associated with MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)

  • meiotic recombination 11 homolog A (S. cerevisiae) (mre11a) antibody
  • MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A) antibody
  • meiotic recombination 11 homolog A (S. cerevisiae) (Mre11a) antibody
  • MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (Mre11a) antibody
  • ATLD antibody
  • HNGS1 antibody
  • MRE11 antibody
  • MRE11B antibody
  • wu:faa63d12 antibody
  • zgc:64018 antibody

Protein level used designations for MRE11A

meiotic recombination 11 homolog A , MRE11 meiotic recombination 11 homolog A (S. cerevisiae) , MRE11 homolog 1 , MRE11 homolog A , double-strand break repair protein MRE11A , meiotic recombination 11 homolog 1 , mmMRE11A , AT-like disease , DNA recombination and repair protein , endo/exonuclease Mre11 , meiotic recombination 11-like protein

GENE ID SPECIES
406637 Danio rerio
737902 Pan troglodytes
100356946 Oryctolagus cuniculus
17535 Mus musculus
4361 Homo sapiens
64046 Rattus norvegicus
494006 Canis lupus familiaris
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