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Browse our anti-MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) Antibodies

Full name:
anti-MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) Antibodies (MSH2)
On www.antibodies-online.com are 158 MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) Antibodies from 28 different suppliers available. Additionally we are shipping MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) Proteins (8) and MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) Kits (5) and many more products for this protein. A total of 185 MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) products are currently listed.
Synonyms:
AI788990, ATMSH2, CG7895, COCA1, Dmel\CG7895, DmNK-4, DROHOXHK4, DROHOXNK4, FCC1, HNPCC, HNPCC1, HOX, LCFS2, msh-2, msh2, MUTS homolog 2, NK-4, NK-4/msh-2, NK4, NK4/msh-2, NKX2.5, Tin, tin/NK4, wu:fc06b02, wu:fc13e09, zgc:55333

All available anti-MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) Antibodies

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Top referenced anti-MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) Antibodies

  1. Human Monoclonal MSH2 Primary Antibody for IHC (fro), IHC (p) - ABIN967509 : Cleaver: It was a very good year for DNA repair. in Cell 1994 (PubMed)
    Show all 8 references for ABIN967509

  2. Human Polyclonal MSH2 Primary Antibody for EIA, FACS - ABIN953526 : Mangoni, Bisanzi, Carozzi, Sani, Biti, Livi, Barletta, Costantini, Gorini: Association between genetic polymorphisms in the XRCC1, XRCC3, XPD, GSTM1, GSTT1, MSH2, MLH1, MSH3, and MGMT genes and radiosensitivity in breast cancer patients. in International journal of radiation oncology, biology, physics 2011 (PubMed)
    Show all 5 references for ABIN953526

  3. Human Monoclonal MSH2 Primary Antibody for WB - ABIN1882267 : Leonardis: Gene symbol: msh2. Disease: hereditary nonpolyposis colorectal cancer. in Human genetics 2006 (PubMed)
    Show all 4 references for ABIN1882267

  4. Human Monoclonal MSH2 Primary Antibody for IHC (p) - ABIN115118 : Kolodner, Hall, Lipford, Kane, Rao, Morrison, Wirth, Finan, Burn, Chapman: Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations. in Genomics 1995 (PubMed)
    Show all 4 references for ABIN115118

  5. Human Monoclonal MSH2 Primary Antibody for ICC, IHC - ABIN1724643 : Palombo, Hughes, Jiricny, Truong, Hsuan: Mismatch repair and cancer. in Nature 1994 (PubMed)
    Show all 2 references for ABIN1724643

  6. Human Polyclonal MSH2 Primary Antibody for IF, IHC - ABIN1534471 : Fishel, Lescoe, Rao, Copeland, Jenkins, Garber, Kane, Kolodner: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. in Cell 1994 (PubMed)

  7. Cow (Bovine) Polyclonal MSH2 Primary Antibody for IHC, WB - ABIN2776761 : Wedrén, Lovmar, Humphreys, Magnusson, Melhus, Syvänen, Kindmark, Landegren, Fermér, Stiger, Persson, Baron, Weiderpass: Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study. in BMC cancer 2009 (PubMed)

  8. Chicken Polyclonal MSH2 Primary Antibody for WB - ABIN2776760 : Höss, Robins, Naven, Pappin, Sgouros, Lindahl: A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein. in The EMBO journal 1999 (PubMed)

More Antibodies against MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) Interaction Partners

Arabidopsis thaliana MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) interaction partners

  1. The expression of AtMutSgamma (MSH7 and MSH2) in Saccharomyces cerevisiae suggest that AtMutSgamma affects yeast genomic stability by recognizing specific mismatches.

  2. The contribution of MutSalpha (MSH2-MSH6) to ultraviolet-induced DNA lesion repair and cell cycle regulation was investigated.

  3. reported that AtMSH2 has a broad range of anti-recombination effects: it suppresses recombination between divergent direct repeats in somatic cells or between homologues from different ecotypes during meiosis

Mouse (Murine) MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) interaction partners

  1. Data show that in mutS homolog 2 protein Msh2(+/-) mice, azathioprine (Aza) induced a high incidence of microsatellite instability (MSI (show EBP Antibodies)) lymphomas in a dose-dependent manner.

  2. In Msh2-/- mice, red meat enhanced survival compared to control (p<0.01) and lowered total tumour burden compared to resistant starch (p<0.167).

  3. Angptl2 (show ANGPTL2 Antibodies)-induced inflammation increases susceptibility to microenvironmental changes, allowing increased oxidative stress and decreased Msh2 expression.

  4. Gut (show GUSB Antibodies) microbes did not induce colorectal cancer in APC (show APC Antibodies)(Min/+)MSH2(-/-) mice through an inflammatory response or the production of DNA mutagens but rather by providing carbohydrate-derived metabolites such as butyrate that fuel hyperproliferation of MSH2(-/-) colon epithelial cells.

  5. MSH2-MSH3 (show MSH3 Antibodies) suppresses chromosomal instability and modulates the tumor spectrum in p53 (show TP53 Antibodies)-deficient tumorigenesis.

  6. Results suggest that MSH2 is rate limiting for expansion in fragile X (show FMR1 Antibodies) premutation mouse model and that MSH2 levels may be a key factor that accounts for tissue-specific differences in expansion risk.

  7. Toxicity, induced by tert (show TERT Antibodies)-butyl-hydroperoxide and potassium bromate, differs in base excision repair proficient (Mpg (show MPG Antibodies) (+/+), Nth1 (show NTHL1 Antibodies) (+/+)) and deficient (Mpg (show MPG Antibodies) (-/-), Nth1 (show NTHL1 Antibodies) (-/-)) mouse embryonic fibroblasts following Msh2 knockdown, was examined.

  8. Medium-spiny striatal neurons-specific deletion of Msh2 was sufficient to eliminate the vast majority of striatal HTT (show HTT Antibodies) CAG expansions in HTT (show HTT Antibodies) CAG knock-in mice.

  9. Enhanced occupancy of Msh2 and Msh3 (show MSH3 Antibodies) proteins is detected downstream of the FXN (show FXN Antibodies) expanded GAA (show GAA Antibodies) repeat, suggesting a model in which Msh2/3 dimers are recruited to this region to repair mismatches.

  10. we show that AID binds cooperatively with UNG and the mismatch repair proteins Msh2-Msh6 to Ig Smu and Sgamma3 regions

Zebrafish MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) interaction partners

  1. Identification and characterization of novel knockout mutants of the three major MMR (show MRC1 Antibodies) genes, mlh1 (show MLH1 Antibodies), msh2, and msh6 (show MSH6 Antibodies), in zebrafish that develop tumors at low frequencies.

Human MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) interaction partners

  1. foot-drop is frequently associated with NEB (show NEB Antibodies) gene mutations . This result supports the indication deriving from the yeast model that BRCA1 driven tumorigenesis may be modulated by MSH2.

  2. Pathogenic mutations were only confined to MSH2 and identified in 28.8% of Singapore families with Hereditary Colorectal Cancer.

  3. Heterozygous germline mutations in any of the mismatch repair (MMR (show MRC1 Antibodies)) genes, MLH1 (show MLH1 Antibodies), MSH2, MSH6 (show MSH6 Antibodies), and PMS2 (show PMS2 Antibodies), cause Lynch syndrome (LS), an autosomal dominant cancer predisposition syndrome.

  4. Authors propose an Alu-mediated recombination model to explain the origin of the cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome.

  5. MSH2, MSH6 (show MSH6 Antibodies), and EXO1 (show EXO1 Antibodies) genes were overexpressed in gastroesophageal cancers.

  6. We identified several genes (FasL (show FASL Antibodies), MSH2, ABCC5 (show ABCC5 Antibodies), CASP3 (show CASP3 Antibodies), and CYP3A4 (show CYP3A4 Antibodies))that showed association with PFS in patients with osteosarcoma. These pharmacogenetic risk factors might be useful to predict treatment outcome

  7. This retrospective cohort study investigated the risk factors associated with the development of colorectal cancer in patients with MLH1 (show MLH1 Antibodies) and MSH2 germline mutations.

  8. The mismatch-binding protein MutS beta, a heterodimer of MSH2 and MSH3, activates ATR in response to DNA double-strand breaks.

  9. Expression levels of DNA repair genes, such as MSH2, may serve as informative biomarkers for identifying patients with T2 Diabetes and coronary artery disease.

  10. Prostate cancer occurs at a younger age mainly for mutations in MSH2 gene.

Fruit Fly (Drosophila melanogaster) MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) interaction partners

  1. Overexpression of Tinman and Pannier resulted in 20% of embryos with ectopic Hand and Sur (show ABCC8 Antibodies) expression. By adding MEF2 (show MYEF2 Antibodies) alongside Tinman and Pannier, an expansion in expression of Hand and Sur (show ABCC8 Antibodies) was observed.

  2. Findings provide mechanistic insight into the brake on myogenesis that occurs during mesoderm specification: twist and tin expression at early stages in turn activate the myogenic inhibitor Him; yet, once Twist or Tin levels decline at mid-embryogenesis, Him is no longer expressed in the mesoderm, and MEF2 (show MYEF2 Antibodies)-dependent muscle differentiation can proceed.

  3. Plasticity in Hox/PBC (show DLAT Antibodies) interaction modes is a common molecular strategy for shaping Hox transcriptional activities.

  4. The enhancers active in the heart progenitor cells and the heart generally are dependent on tinman gene activity, whereas those active in non-cardiac mesoderm are often bound neutrally by Tinman

  5. Genetic interaction analysis shows that spir functionally interacts with Dorsocross, tin, and pannier to properly specify the cardiac fate.

  6. Tin is a direct regulator of midline in fly heart development.

  7. wg and dpp (show TGFb Antibodies) contribute progressively to the elaboration of the expression pattern of the mesoderm-specific homeobox (show PRRX1 Antibodies)-containing gene tinman (tin), and the overlap of wg and dpp (show TGFb Antibodies) in the presence of tin-expressing cells directs cardiac-specific differentiation

  8. We show that salivary gland posterior migration requires the activities of genes that position the visceral mesoderm precursors, such as heartless, thickveins, and tinman, but does not require a differentiated visceral mesoderm.

  9. one of the major functions of mid and H15 during cardioblast development is the re-activation of tin expression at a stage when the induction of tin by Dpp (show TGFb Antibodies) in the dorsal mesoderm has ceased

  10. dSUR is regulated by tinman and plays a protective role against hypoxic stress and pacing-induced heart failure

MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) Antigen Profile

Antigen Summary

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2)

  • mismatch repair protein (MSH2) antibody
  • DNA mismatch repair protein Msh2 (MSH2) antibody
  • mutS homolog 2 (E. coli) (Msh2) antibody
  • mutS homolog 2 (E. coli) (msh2) antibody
  • mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) antibody
  • tinman (tin) antibody
  • AI788990 antibody
  • ATMSH2 antibody
  • CG7895 antibody
  • COCA1 antibody
  • Dmel\CG7895 antibody
  • DmNK-4 antibody
  • DROHOXHK4 antibody
  • DROHOXNK4 antibody
  • FCC1 antibody
  • HNPCC antibody
  • HNPCC1 antibody
  • HOX antibody
  • LCFS2 antibody
  • msh-2 antibody
  • msh2 antibody
  • MUTS homolog 2 antibody
  • NK-4 antibody
  • NK-4/msh-2 antibody
  • NK4 antibody
  • NK4/msh-2 antibody
  • NKX2.5 antibody
  • Tin antibody
  • tin/NK4 antibody
  • wu:fc06b02 antibody
  • wu:fc13e09 antibody
  • zgc:55333 antibody

Protein level used designations for MSH2

mismatch repair protein , DNA mismatch repair protein Msh2 , mutS protein homolog 2 , mismatch repair protein Msh2 , hMSH2 , mutS-like protein 2 , MutS-like protein 2 , CG7895-PA , muscle-specific-homeodomain-2 , tin-PA

GENE ID SPECIES
100268052 Vitis vinifera
821383 Arabidopsis thaliana
17685 Mus musculus
81709 Rattus norvegicus
406845 Danio rerio
4436 Homo sapiens
378799 Gallus gallus
494002 Canis lupus familiaris
100337661 Sus scrofa
533115 Bos taurus
42536 Drosophila melanogaster
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