Browse our anti-NEIL1 (NEIL1) Antibodies

Full name:
anti-Endonuclease VIII-Like 1 Antibodies (NEIL1)
On www.antibodies-online.com are 68 Endonuclease VIII-Like 1 (NEIL1) Antibodies from 19 different suppliers available. Additionally we are shipping NEIL1 Proteins (13) and NEIL1 Kits (7) and many more products for this protein. A total of 96 NEIL1 products are currently listed.
Synonyms:
2810450N13Rik, FPG1, hFPG1, Nei1
list all antibodies Gene Name GeneID UniProt
NEIL1 367090  
NEIL1 79661 Q96FI4
NEIL1 72774 Q8K4Q6

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Most Popular Reactivities for anti-NEIL1 (NEIL1) Antibodies

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anti-Mouse (Murine) NEIL1 Antibodies:

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Top referenced anti-NEIL1 Antibodies

  1. Human Polyclonal NEIL1 Primary Antibody for EIA, WB - ABIN953643 : Forsbring, Vik, Dalhus, Karlsen, Bergquist, Schrumpf, Bjørås, Boberg, Alseth: Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. in Carcinogenesis 2009 (PubMed)
    Show all 5 references for 953643

  2. Human Polyclonal NEIL1 Primary Antibody for WB - ABIN653649 : Zhao, Krishnamurthy, Burrows, David: Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts. in Biochemistry 2010 (PubMed)
    Show all 3 references for 653649

  3. Human Polyclonal NEIL1 Primary Antibody for IHC, ELISA - ABIN184936 : Hazra, Izumi, Boldogh, Imhoff, Kow, Jaruga, Dizdaroglu, Mitra: Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

More Antibodies against NEIL1 Interaction Partners

Human Endonuclease VIII-Like 1 (NEIL1) interaction partners

  1. identified the c-Jun N-terminal kinase 1 (JNK1 (show MAPK8 Antibodies)) as the kinase involved in the phosphorylation of NEIL1

  2. NEIL1 (rs5745908) is associated with Behcet's disease. The genetic association in NEIL1 is a predicted splice donor variant that may introduce a deleterious intron retention and result in a noncoding transcript variant.

  3. cellular NEIL1 is regulated by the UPP (show UPP1 Antibodies) mediated by the E3 ubiquitin ligases Mule (show HUWE1 Antibodies) and TRIM26 (show TRIM26 Antibodies), which plays a vital role in co-ordinating the cellular response to DNA damage.

  4. Nei (show PMCH Antibodies) Like DNA Glycosylase 1 (NEIL1) as a likely candidate gene due to its crucial role in B-cell activation (show BLNK Antibodies) and terminal differentiation.

  5. The abnormal expressions of NEIL1, NEIL2 (show NEIL2 Antibodies), and NEIL3 (show NEIL3 Antibodies) are involved in cancer through their association with the somatic mutation load.

  6. NEIL1 and NEIL2 (show NEIL2 Antibodies) cooperate with TDG (show TDG Antibodies) during base excision: TDG (show TDG Antibodies) occupies the abasic site and is displaced by NEILs, which further process the baseless sugar, thereby stimulating TDG (show TDG Antibodies)-substrate turnover.

  7. Findings suggesting that DNA glycosylase NEIL1 c.C844T is a defective allele.

  8. NEIL1 forms a multiprotein complex with DNA replication proteins via its C-terminal domain, allowing recruitment at the replication fork.

  9. Results show that YB-1 (show YBX1 Antibodies) interferes negatively with the AP site DNA cleavage activity of both APE1 (show APEX1 Antibodies) and NEIL1 for ssDNA and bubble structures.

  10. Rad9 (show RAD9A Antibodies) regulates base excision repair by controlling NEIL1 transcription.

Mouse (Murine) Endonuclease VIII-Like 1 (NEIL1) interaction partners

  1. Collectively the data suggest that NEIL1-initiated repair of a subset of ROS (show ROS1 Antibodies)-induced DNA base lesions may be insufficient to prevent the initiation of inflammatory pathways during chronic UV exposure in mouse skin.

  2. Rad9 (show RAD9A Antibodies) regulates base excision repair by controlling Neil1 protein stability in mouse embryonic stem cells.

  3. Hypersensitivity to H2O2 caused by NEIL1 knockdown was more significant in S phase than in G1 phase, suggesting that NEIL1 has an important role during S phase.

  4. Data indicate that maternal folate depletion during pregnancy and high-fat feeding from weaning altered gene expression of Ogg1 (show OGG1 Antibodies), Neil1, Mutyh (show MUTYH Antibodies) and Xrcc1 (show XRCC1 Antibodies) in the brain of adult offspring.

  5. one role for Neil3 (show NEIL3 Antibodies) and NEIL1 is to repair DNA base damages in telomeres in vivo and that Neil3 (show NEIL3 Antibodies) and Neil1 may function in quadruplex-mediated cellular events, such as gene regulation via removal of damaged bases from quadruplex DNA.

  6. binds to the BRCT domain of PARP-1 (show PARP1 Antibodies)

  7. Neil1 contributes to germline and somatic Huntington's disease CAG repeat (show CELF3 Antibodies) expansion.

  8. Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice.

  9. NEIL1 deficiency results in an increased susceptibility to obesity and related complications potentially by lowering the threshold for tolerance of cellular oxidative stress in neil1(-/-) mice.

  10. NEIL1 is involved in nucleotide excision repair of(5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines, in addition to its function as a DNA glycosylase in base excision repair.

NEIL1 Antigen Profile

Antigen Summary

This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NEIL1

  • nei endonuclease VIII-like 1 (E. coli) (Neil1) antibody
  • nei endonuclease VIII-like 1 (E. coli) (NEIL1) antibody
  • 2810450N13Rik antibody
  • FPG1 antibody
  • hFPG1 antibody
  • Nei1 antibody

Protein level used designations for NEIL1

endonuclease VIII-like 1 , DNA glycosylase/AP lyase Neil1 , DNA-(apurinic or apyrimidinic site) lyase Neil1 , NEH1 , endonuclease 8-like 1 , endonuclease VIII , nei homolog 1 , nei-like protein 1

GENE ID SPECIES
367090 Rattus norvegicus
79661 Homo sapiens
72774 Mus musculus
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