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Browse our Nonhomologous End-Joining Factor 1 (NHEJ1) ELISA Kits

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Nonhomologous End-Joining Factor 1 ELISA Kits (NHEJ1)
On www.antibodies-online.com are 3 Nonhomologous End-Joining Factor 1 (NHEJ1) ELISA Kits from 1 different suppliers available. Additionally we are shipping Nonhomologous End-Joining Factor 1 Antibodies (87) and Nonhomologous End-Joining Factor 1 Proteins (7) and many more products for this protein. A total of 103 Nonhomologous End-Joining Factor 1 products are currently listed.
Synonyms:
1700029B21Rik, cernunnos, NHEJ1, XLF, zgc:85657
list all ELISA KIts Gene Name GeneID UniProt
NHEJ1 79840 Q9H9Q4
NHEJ1 75570 Q3KNJ2
NHEJ1 363251 Q6AYI4

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More ELISA Kits for Nonhomologous End-Joining Factor 1 Interaction Partners

Human Nonhomologous End-Joining Factor 1 (NHEJ1) interaction partners

  1. using dual- and quadruple-trap optical tweezers combined with fluorescence microscopy, we show how human XRCC4 (show XRCC4 ELISA Kits), XLF and XRCC4 (show XRCC4 ELISA Kits)-XLF complexes interact with DNA in real time

  2. The data suggest that XLF has multiple functions in DNA repair, and they offer potential explanations for the pleiotropic phenotypes associated with XLF deficiency.

  3. PC4 (show IFRD1 ELISA Kits) protects esophageal squamous cell carcinoma cells from IR-induced death by enhancing the nonhomologous end joining-promoting activity of XLF.

  4. Phosphorylation of XLF impairs non-homologous end-joining DNA repair.

  5. Werner syndrome protein positively regulates XRCC4-like factor transcription.

  6. Human XLF is a non-essential, but critical, classic non-homologous end-joining -repair factor.

  7. An induced pluripotent stem cell (iPSC) model of XLF deficiency, which accurately replicates the double-strand break repair deficiency observed in XLF syndrome patients, is reported.

  8. Data indicate that Ku70 (show XRCC6 ELISA Kits)/Ku80 (show XRCC5 ELISA Kits) facilitates the cooperative binding of multiple XRCC4 (show XRCC4 ELISA Kits)/Ligase IV (XL) and XLF molecules to DNA.

  9. XRCC4 (show XRCC4 ELISA Kits) and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. (Review)

  10. Cernunnos deficiency results in chronic activation of the DNA damage response, P53 (show TP53 ELISA Kits)-driven upregulation of proapoptotic factors, leading to decreased thymocyte viability and a qualitative alteration of the T cell repertoire in both humans and mice.

Mouse (Murine) Nonhomologous End-Joining Factor 1 (NHEJ1) interaction partners

  1. These results reveal an unanticipated functional interplay between the RAG complex and XLF in repairing RAG-induced DNA breaks and maintaining genome integrity during antigen receptor gene assembly.

  2. XLF-deficient mice recapitulate the age-dependent lymphocytopenia of patients.

  3. XLF functionally overlaps with DNA-PKcs in normal development, promotion of genomic stability in fibroblasts, and in IgH class switch recombination in mature B cells.

  4. Cernunnos deficiency results in chronic activation of the DNA damage response, P53 (show TP53 ELISA Kits)-driven upregulation of proapoptotic factors, leading to decreased thymocyte viability and a qualitative alteration of the T cell repertoire in both humans and mice.

  5. XLF repair protein and 53BP1 (show TP53BP1 ELISA Kits) DNA damage response factor have overlapping functions in end joining and lymphocyte development

  6. find that combined XLF/53BP1 (show TP53BP1 ELISA Kits) deficiency in mice severely impairs C-NHEJ, V(D)J recombination, and lymphocyte development while also leading to general genomic instability and growth defects

  7. XLF, ATM and H2AX all have fundamental roles in processing and joining DNA ends during V(D)J recombination, but that these roles have been masked by unanticipated functional redundancies

  8. in mice, Cernunnos-XLF is essential for normal NHEJ-mediated repair of DNA DSBs and the Cernunnos-XLF acts as a genomic caretaker to prevent genomic instability

Nonhomologous End-Joining Factor 1 (NHEJ1) Antigen Profile

Antigen Summary

Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

Alternative names and synonyms associated with Nonhomologous End-Joining Factor 1 (NHEJ1)

  • nonhomologous end-joining factor 1 (NHEJ1) Elisa Kit
  • nonhomologous end-joining factor 1 (nhej1) Elisa Kit
  • nonhomologous end-joining factor 1 (LOC100353092) Elisa Kit
  • nonhomologous end-joining factor 1 (Nhej1) Elisa Kit
  • 1700029B21Rik Elisa Kit
  • cernunnos Elisa Kit
  • NHEJ1 Elisa Kit
  • XLF Elisa Kit
  • zgc:85657 Elisa Kit

Protein level used designations for NHEJ1

nonhomologous end-joining factor 1 , non-homologous end-joining factor 1 , XRCC4-like factor , protein cernunnos

GENE ID SPECIES
424205 Gallus gallus
445871 Xenopus laevis
509157 Bos taurus
742646 Pan troglodytes
100145147 Xenopus (Silurana) tropicalis
100153546 Sus scrofa
100353092 Oryctolagus cuniculus
100581628 Nomascus leucogenys
406593 Danio rerio
79840 Homo sapiens
75570 Mus musculus
363251 Rattus norvegicus
610570 Canis lupus familiaris
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