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Partner and Localizer of BRCA2 ELISA Kits (PALB2)
On www.antibodies-online.com are 2 Partner and Localizer of BRCA2 (PALB2) ELISA Kits from 1 different suppliers available. Additionally we are shipping PALB2 Antibodies (69) and PALB2 Proteins (3) and many more products for this protein. A total of 80 PALB2 products are currently listed.
Synonyms:
4732427B05, BC066140, FANCN, PALB2, PNCA3, RGD1304759, si:ch211-14k19.9
list all ELISA KIts Gene Name GeneID UniProt
PALB2 79728 Q86YC2
PALB2 233826 Q3U0P1
Rat PALB2 PALB2 293452  

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PALB2 (PALB2) ELISA Kits by Reactivity

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More ELISA Kits for PALB2 Interaction Partners

Human Partner and Localizer of BRCA2 (PALB2) interaction partners

  1. PALB2 rare variants were associated with an increased risk of breast cancer.

  2. our findings highlight a critical importance of PALB2 phosphorylation as a novel regulatory step in genome maintenance after genotoxic stress.

  3. identification of a hidden nuclear export signal (NES (show NES ELISA Kits)) within the WD40 domain (show DCAF12L2 ELISA Kits) of PALB2 and found that the W1038X truncation leads to the exposure of this NES (show NES ELISA Kits) to CRM1 (show XPO1 ELISA Kits), an export protein

  4. PALB2 mutation along with BRCA1 mutation confers chemoresistance in breast cancer.

  5. Germline mutation in PALB2 gene is associated with neoadjuvant therapy response in triple negative breast patients.

  6. Germline PALB2 mutation was found in patients with hereditary and sporadic gastric cancer.

  7. PALB2 is involved in BC risk.

  8. we describe a genetic approach to examine the functional significance of the interaction between BRCA2 (show BRCA2 ELISA Kits) and PALB2 by generating a knock-in mouse model of Brca2 (show BRCA2 ELISA Kits) carrying a single amino acid change (Gly25Arg, Brca2G25R) that disrupts this interaction. In addition, we have combined Brca2G25R homozygosity as well as hemizygosity with Palb2 and Trp53 (show TP53 ELISA Kits) heterozygosity .

  9. Results identified novel intronic mutations in PALB2 gene associated with early-onset breast cancer patients from Turkey. PABL2 mutations accounted for 4.03 % in BRCA1/2-negative Turkish patients.

  10. rs120963 and rs249954 of the PALB2 gene are associated with increased breast cancer risk, and the association of rs249935 with breast cancer risk may be modified by the tumor pathological characteristics.

Mouse (Murine) Partner and Localizer of BRCA2 (PALB2) interaction partners

  1. we describe a genetic approach to examine the functional significance of the interaction between BRCA2 (show BRCA2 ELISA Kits) and PALB2 by generating a knock-in mouse model of Brca2 (show BRCA2 ELISA Kits) carrying a single amino acid change (Gly25Arg, Brca2G25R) that disrupts this interaction. In addition, we have combined Brca2G25R homozygosity as well as hemizygosity with Palb2 and Trp53 (show TP53 ELISA Kits) heterozygosity .

  2. results underscore the in vivo importance of the PALB2-BRCA1 complex formation in DSB repair and male meiosis

  3. Palb2 synergizes with Trp53 (show TP53 ELISA Kits) to suppress mammary tumor formation in a model of inherited breast cancer.

  4. A key function for PALB2 is to interact with and to build up appropriate communication between BRCA1 (show BRCA1 ELISA Kits) and BRCA2 (show BRCA2 ELISA Kits).

PALB2 Antigen Profile

Antigen Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.

Alternative names and synonyms associated with PALB2

  • partner and localizer of BRCA2 (PALB2) Elisa Kit
  • partner and localizer of BRCA2 (palb2) Elisa Kit
  • partner and localizer of BRCA2 (LOC100356031) Elisa Kit
  • partner and localizer of BRCA2 (Palb2) Elisa Kit
  • 4732427B05 Elisa Kit
  • BC066140 Elisa Kit
  • FANCN Elisa Kit
  • PALB2 Elisa Kit
  • PNCA3 Elisa Kit
  • RGD1304759 Elisa Kit
  • si:ch211-14k19.9 Elisa Kit

Protein level used designations for PALB2

partner and localizer of BRCA2 , Fanconi N , Fanconi anemia , complementation group N , partner and localizer of BRCA2-like

GENE ID SPECIES
416572 Gallus gallus
453988 Pan troglodytes
558923 Danio rerio
608527 Canis lupus familiaris
700843 Macaca mulatta
733293 Xenopus laevis
100069097 Equus caballus
100356031 Oryctolagus cuniculus
100408318 Callithrix jacchus
100436331 Pongo abelii
100479015 Ailuropoda melanoleuca
100523630 Sus scrofa
100593417 Nomascus leucogenys
79728 Homo sapiens
233826 Mus musculus
293452 Rattus norvegicus
507620 Bos taurus
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