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Browse our PMS2 (PMS2) ELISA Kits

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PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) ELISA Kits (PMS2)
On are 0 PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) ELISA Kits from different suppliers available. Additionally we are shipping PMS2 Antibodies (100) and PMS2 Proteins (6) and many more products for this protein. A total of 113 PMS2 products are currently listed.
AW555130, HNPCC4, PMS2CL, Pmsl2
list all ELISA KIts Gene Name GeneID UniProt
Human PMS2 PMS2 5395 P54278
Mouse PMS2 PMS2 18861  
Rat PMS2 PMS2 288479  

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More ELISA Kits for PMS2 Interaction Partners

Human PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) interaction partners

  1. Loss of MLH-1 (show MLH1 ELISA Kits)/PMS-2 expression was associated with right-colon location, poor and mucinous differentiation and dense lymphocytic infiltration in colorectal adenocarcinoma.

  2. Heterozygous germline mutations in any of the mismatch repair (MMR (show MRC1 ELISA Kits)) genes, MLH1 (show MLH1 ELISA Kits), MSH2 (show MSH2 ELISA Kits), MSH6 (show MSH6 ELISA Kits), and PMS2, cause Lynch syndrome (LS), an autosomal dominant cancer predisposition syndrome.

  3. A reliable tool for accurate molecular analysis of genes containing multiple copies of highly homologous sequences and improved PMS2 molecular analysis for patients with Lynch syndrome.

  4. These results demonstrate a functional role for PMS2 to protect against prostate cancer progression by enhancing apoptosis of prostate cancer cells and by inhibiting cell proliferation, migration, and invasion in vitro as well as tumor growth in vivo.

  5. MutSalpha, proliferating cell nuclear antigen (show PCNA ELISA Kits), and replication factor C activate MutLalpha endonuclease to remove the 1-nucleotide Okazaki fragment flaps

  6. Our genotype-phenotype study of c.2002A>G illustrates that an extremely low level of PMS2 expression likely delays cancer onset, a feature that could be exploited in cancer preventive intervention.

  7. Report high frequency of MLH1 (show MLH1 ELISA Kits) germline mutations in Lynch syndrome patients with colorectal and endometrial carcinoma demonstrating isolated loss of PMS2 immunohistochemical expression.

  8. we collected information on 66 MLH1 (show MLH1 ELISA Kits), 24 MSH2 (show MSH2 ELISA Kits) and 6 PMS2 nucleotide variants reported to be associated with altered expression of at least one of these alternative transcripts, and in many instances reported as splicing mutations

  9. Another MMR (show MRC1 ELISA Kits) protein PMS2 also displayed a declined expression while being in a later stage of transformation.

  10. Some uterine carcinosarcomas show loss of PMS2.

Mouse (Murine) PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) interaction partners

  1. Primary function of Pms2 during spermatogenesis is to stabilize Mlh1 (show MLH1 ELISA Kits) levels prior to its critical crossing over function with Mlh3. An intact Pms2 ATPase (show DNAH8 ELISA Kits) domain is not essential for male fertility.

  2. Pms2 specifically suppresses large expansions of a pathogenic trinucleotide repeat sequence in neuronal tissues, possibly acting independently of the canonical mismatch repair pathway.

  3. Down-regulation of PMS2 is associated with initiation and growth of neuroblastoma (show ARHGEF16 ELISA Kits) and brain tumour multicellular spheroids.

  4. the integrity of the MLH1 (show MLH1 ELISA Kits) ATPase (show DNAH8 ELISA Kits) domain is more critical than the PMS2 ATPase (show DNAH8 ELISA Kits) domain for normal DNA mismatch repair functions

  5. Data show that the PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance and tumor suppression.

  6. Role for mismatch repair proteins Msh2 (show MSH2 ELISA Kits), Mlh1 (show MLH1 ELISA Kits), and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions.

  7. We found that MLH1 (show MLH1 ELISA Kits) and PMS2 have functional nuclear localization signals (NLS (show ALDH1A2 ELISA Kits)) and nuclear export sequences, yet nuclear import depended on their C-terminal dimerization to form MutLalpha

  8. Pms2 has a role in the prevention of tandem CC --> TT substitutions induced by ultraviolet radiation and oxidative stress.

  9. Data show partial functional redundancy between MLH3 and PMS2 orthologues for mutation avoidance and show a role for Mlh3 in gastrointestinal and extragastrointestinal tumor suppression.

  10. In order to determine the effect of Pms2-deficiency on mutation, mutant frequencies in the endogenous Hprt (show HPRT1 ELISA Kits) gene of lymphocytes from male Pms2(-/-), Pms2(+/-), and Pms2(+/+) mice, was measured.

PMS2 Antigen Profile

Antigen Summary

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with PMS2

  • PMS2 postmeiotic segregation increased 2 (S. cerevisiae) (PMS2) Elisa Kit
  • mismatch repair endonuclease PMS2 (Tsp_08837) Elisa Kit
  • postmeiotic segregation increased 2 (S. cerevisiae) (Pms2) Elisa Kit
  • AW555130 Elisa Kit
  • HNPCC4 Elisa Kit
  • PMS2CL Elisa Kit
  • Pmsl2 Elisa Kit

Protein level used designations for PMS2

mismatch repair endonuclease PMS2 , DNA mismatch repair protein PMS2 , H_DJ0042M02.9 , PMS1 protein homolog 2 , PMS2 postmeiotic segregation increased 2

479751 Canis lupus familiaris
100514342 Sus scrofa
10897854 Trichinella spiralis
5395 Homo sapiens
463257 Pan troglodytes
101752182 Gallus gallus
527039 Bos taurus
18861 Mus musculus
288479 Rattus norvegicus
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