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Browse our RAD51C Proteins (RAD51C)

Full name:
RAD51 Homolog C (S. Cerevisiae) Proteins (RAD51C)
On www.antibodies-online.com are 6 RAD51 Homolog C (S. Cerevisiae) (RAD51C) Proteins from 4 different suppliers available. Additionally we are shipping RAD51C Antibodies (94) and many more products for this protein. A total of 108 RAD51C products are currently listed.
Synonyms:
ATRAD51C, BROVCA3, CG2412, Dm CG2412, Dmel\\CG2412, F4L23.21, FANCO, R51H3, Rad51c, RAD51L2, RAS associated with diabetes protein 51C, RGD1563765, zgc:101596
list all proteins Gene Name GeneID UniProt
Rat RAD51C RAD51C 497976  
RAD51C 114714 Q924H5
RAD51C 5889 O43502

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RAD51C Proteins (RAD51C) by Origin

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More Proteins for RAD51C Interaction Partners

Arabidopsis thaliana RAD51 Homolog C (S. Cerevisiae) (RAD51C) interaction partners

  1. AtRAD51C and SWI (show SMARCA1 Proteins) may function at distinct stages of meiosis.

  2. AtRAD51C is essential for normal meiosis and is probably required for homologous synapsis.[AtRAD51C]

  3. Crossing of RAD51C mutant with wild-type plants showed defective male and female gametogeneses as evidenced by lack of seed production. Furthermore, meiosis was severely disturbed in the mutant.

Mouse (Murine) RAD51 Homolog C (S. Cerevisiae) (RAD51C) interaction partners

  1. a critical synergy between Rad51c and Trp53 (show TP53 Proteins) in tumour progression and provide a predictable in vivo model system for studying mechanisms of Rad51c-mediated carcinogenesis

  2. These results imply that adequate expression of Rad51C in mammalian cells is essential for maintaining genomic stability and sister chromatid cohesion to prevent malignant transformation.

  3. the RAD51C-XRCC3-associated Holliday junction resolvase complex associates with crossovers and may play an essential role in the resolution of recombination intermediates prior to chromosome segregation

  4. RAD51C has a late role in meiotic recombination.

  5. Rad51c mutation in DH-cis (show CISH Proteins) mice promoted the development of tumors of specialized sebaceous glands and suppressed tumors characteristic of Trp53 (show TP53 Proteins) mutation. In addition, DH-cis (show CISH Proteins) females developed tumors significantly earlier than any other group.

  6. DNA replication licensing factor MCM2 (show MCM2 Proteins) and DNA mismatch repair (MMR (show MRC1 Proteins)) protein MSH2 (show MSH2 Proteins) were confirmed to be present in co-precipitations with MmRAD51C.

Human RAD51 Homolog C (S. Cerevisiae) (RAD51C) interaction partners

  1. RAD51C mutations were identified in 0.5 % of Danish families.

  2. RAD51C mutation is not associated with high-risk patients from Serbian hereditary breast/ovarian cancer.

  3. a mutation analysis in 171 high-risk BRCA1 and BRCA2 (show BRCA2 Proteins) negative ovarian cancer patients, to evaluate the frequency of hereditary RAD51C and RAD51D (show RAD51D Proteins) variants in Czech population, is reported.

  4. Novel Rad51C splice variants occur in colorectal tumors and cells: Variant 1 without exon-7, Variant 2 without exon 6 and 7 , or Variant 3 without exon 7 and 8. They are associated with FANCD2 foci positive colorectal tumors and microsatellite stability.

  5. conclude that the woman has two potential disease-causing mutations and that predictive testing of family members should include both the RAD51C and BRCA2 (show BRCA2 Proteins) mutation

  6. RAD51C and RAD51D (show RAD51D Proteins) are moderate ovarian cancer susceptibility genes.

  7. RAD51C mutation is associated with breast and ovarian cancer.

  8. The effect of common single nucleotide polymorphisms (SNPs) in non-coding regions of RAD51C in modulating the risk of breast cancer was investigated.

  9. Mutations in RAD51C are associated with drug resistance in breast cancer.

  10. the Rad51C promoter fragment can be used to transcriptionally target cancer cells.

RAD51C Protein Profile

Protein Summary

This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Alternative names and synonyms associated with RAD51C

  • RAD51 homolog C (S. cerevisiae) (RAD51C)
  • RAD51 paralog C (Rad51c)
  • RAD51 paralog C (RAD51C)
  • CG2412 gene product from transcript CG2412-RB (Rad51C)
  • rad51 homolog C (S. cerevisiae) (rad51c)
  • RAD51 paralog C (rad51c)
  • Rad51 DNA recombinase 3 (RAD51C)
  • RAD51C protein (RAD51C)
  • RAD51 homolog C (Rad51c)
  • DNA repair protein RAD51 homolog 3 (RAD51C)
  • ATRAD51C protein
  • BROVCA3 protein
  • CG2412 protein
  • Dm CG2412 protein
  • Dmel\\CG2412 protein
  • F4L23.21 protein
  • FANCO protein
  • R51H3 protein
  • Rad51c protein
  • RAD51L2 protein
  • RAS associated with diabetes protein 51C protein
  • RGD1563765 protein
  • zgc:101596 protein

Protein level used designations for RAD51C

Rad51 homolog c , RAD51 homolog C , CG2412-PB , Rad51C-PB , RAD51 homolog C (S. cerevisiae) , DNA repair protein RAD51 homolog 3 , Rad51 DNA recombinase 3 , RAD51C protein , RAD51-like protein 2 , yeast RAD51 homolog 3

GENE ID SPECIES
480573 Canis lupus familiaris
497976 Rattus norvegicus
540886 Bos taurus
100070966 Equus caballus
100518577 Sus scrofa
35937 Drosophila melanogaster
417626 Gallus gallus
450081 Danio rerio
455162 Pan troglodytes
548416 Xenopus (Silurana) tropicalis
714828 Macaca mulatta
8250454 Micromonas sp. RCC299
9681081 Micromonas pusilla CCMP1545
100192184 Triticum aestivum
100286824 Nasonia vitripennis
100339674 Oryctolagus cuniculus
100583086 Nomascus leucogenys
819136 Arabidopsis thaliana
114714 Mus musculus
5889 Homo sapiens
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