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Browse our anti-TP53BP1 (TP53BP1) Antibodies

Full name:
anti-Tumor Protein P53 Binding Protein 1 Antibodies (TP53BP1)
On are 157 Tumor Protein P53 Binding Protein 1 (TP53BP1) Antibodies from 24 different suppliers available. Additionally we are shipping TP53BP1 Kits (9) and TP53BP1 Proteins (2) and many more products for this protein. A total of 170 TP53BP1 products are currently listed.
53BP1, m53BP1, MGC160112, p202, Tp53bp1, Trp53bp1
list all antibodies Gene Name GeneID UniProt
TP53BP1 27223 P70399
TP53BP1 7158 Q12888
TP53BP1 296099  

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Most Popular Reactivities for anti-TP53BP1 (TP53BP1) Antibodies

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anti-Mouse (Murine) TP53BP1 Antibodies:

anti-Human TP53BP1 Antibodies:

anti-Rat (Rattus) TP53BP1 Antibodies:

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Top referenced anti-TP53BP1 Antibodies

  1. Human Monoclonal TP53BP1 Primary Antibody for BI, WB - ABIN968860 : Iwabuchi, Bartel, Li, Marraccino, Fields: Two cellular proteins that bind to wild-type but not mutant p53. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 3 references for ABIN968860

  2. Human Monoclonal TP53BP1 Primary Antibody for FACS, IHC - ABIN1724821 : Nakada, Yonamine, Matsuo: RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1. in Cancer research 2012 (PubMed)
    Show all 2 references for ABIN1724821

  3. Human Polyclonal TP53BP1 Primary Antibody for IF (p), IHC (p) - ABIN682993 : Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis. in The Journal of biological chemistry 2015 (PubMed)

More Antibodies against TP53BP1 Interaction Partners

Mouse (Murine) Tumor Protein P53 Binding Protein 1 (TP53BP1) interaction partners

  1. Study showed that mammalian cells use microtubules in the cytoplasm to promote the mobility of sites of DNA damage in the nucleus; molecular details of this process remain to be determined, the main players, including the MOB (show SGMS1 Antibodies) domain of 53BP1, the linker of the nucleoskeleton, and cytoskeleton complex, kinesins, and microtubules are now known, allowing further study.

  2. These experiments define a novel requirement for 53BP1 in the fusions of DNA-PKcs (show PRKDC Antibodies)-deficient telomeres throughout the cell cycle.

  3. Study concludes that only the 53BP1 status in DNA lesions, induced by UVA or gamma-rays, is affected by A-type lamin (show LMNA Antibodies) deficiency, which was not observed for heterochromatin-related proteins HP1beta (show CBX1 Antibodies) and BMI1 (show BMI1 Antibodies).

  4. Binding of 53BP1 to methyl K810 occurs on E2 promoter binding factor (show E2F1 Antibodies) target genes and allows pRb (show PGR Antibodies) activity to be effectively integrated with the DNA damage response.

  5. study uncovers novel ATM (show ATM Antibodies)-independent functions for 53BP1 in the suppression of oncogenic translocations and in radioprotection

  6. Study concludes that 53BP1 promotes productive class switch recombination and suppresses mutagenic DNA repair through distinct phosphodependent interactions with RIF1 (show RIF1 Antibodies) and PTIP (show PAXIP1 Antibodies).

  7. Thus, RIF1 and 53BP1 cooperate to block DSB resection to promote NHEJ in G1, which is antagonized by BRCA1 in S phase to ensure a switch of DSB repair mode to homologous recombination

  8. loss of 53BP1 alters the translocatome by increasing rearrangements to intergenic regions.

  9. A mutant lacking the oligomerization domain (53BP1(oligo)) was only modestly impaired in promoting NHEJ of dysfunctional telomeres and showed no defect with regard to the repression of CtIP (show RBBP8 Antibodies).

  10. data establish Rif1 (show RIF1 Antibodies) as an important contributor to the control of double-strand break repair by 53BP1

Human Tumor Protein P53 Binding Protein 1 (TP53BP1) interaction partners

  1. the interaction of 53BP1 with gammaH2AX (show H2AFX Antibodies) is required for sustaining the 53BP1-dependent focal concentration of activated ATM (show ATM Antibodies) that facilitates repair of DNA double-strand breaks in heterochromatin in G1.

  2. cryo-EM structure of a dimerized human 53BP1 fragment bound to a H4K20me2-containing and H2AK15ub-containing nucleosome core particle at 4.5 A resolution

  3. The study shows higher expression of gamma-H2AX (show H2AFX Antibodies) and 53BP1 foci in rectal cancer patients compared with healthy individuals. Yet the data in vitro were not predictive in regard to the radiotherapy outcome.

  4. For both, gamma-H2AX (show H2AFX Antibodies) and 53BP1, the cellular focus number as well as the percentage of positive cells did not differ between patients with clinically isolated syndrome/early relapsing-remitting multiple sclerosis and healthy controls.

  5. Impaired TIP60 (show KAT5 Antibodies)-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 (show UIMC1 Antibodies) in Fanconi anemia (show PALB2 Antibodies) pathway-deficient cells.

  6. Depleting 53BP1, which slows cNHEJ, fully rescues the nuclear and cytogenetic abnormalities seen with EEPD1 depletion

  7. Suggest 53BP1 may serve as a candidate biomarker for predicting prognosis and disease development in colorectal cancer.

  8. After nanogold treatment, an inverse correlation between the formation of 53BP1 foci and micronuclei generation was observed. The robust 53BP1 recruitment resulted in reduced micronuclei production

  9. Studies performed genotyping analyses of eight functional CDKN1A p21 (show CDKN1A Antibodies), oncoprotein p53 (show TP53 Antibodies), TP53BP1 protein and tumor protein p73 (show TP73 Antibodies) single nucleotide polymorphisms (SNPs) in 330 gastric cardia adenocarcinoma (GCA (show NPR1 Antibodies)) cases and 608 controls in a Chinese population.

  10. we generated two HEP (show EPHB6 Antibodies)-2 cell lines with a stable knockdown of MDC1 (show MDC1 Antibodies) or 53BP1 with short hairpin RNA (shRNA), respectively, and investigated the effect of MDC1 (show MDC1 Antibodies) and 53BP1 on cell radiosensitivity

TP53BP1 Antigen Profile

Antigen Summary

May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Binds to sites of DNA damage. Plays a role in the response to DNA damage (By similarity).

Alternative names and synonyms associated with TP53BP1

  • tumor protein p53 binding protein 1 (TP53BP1) antibody
  • tumor protein p53 binding protein 1 (tp53bp1) antibody
  • tumor protein p53 binding protein 1 (predicted), 5 prime (TP53BP1) antibody
  • transformation related protein 53 binding protein 1 (Trp53bp1) antibody
  • tumor protein p53 binding protein 1 (Tp53bp1) antibody
  • 53BP1 antibody
  • m53BP1 antibody
  • MGC160112 antibody
  • p202 antibody
  • Tp53bp1 antibody
  • Trp53bp1 antibody

Protein level used designations for TP53BP1

tumor protein p53 binding protein 1 , tumor protein p53 binding protein, 1 , tumor suppressor p53-binding protein 1-like , tumor protein p53 binding protein 1 (predicted), 5 prime , tumor protein p53 binding protein 1 (predicted), 3 prime , murine p53-binding protein , p53-binding protein 1 , p53BP1 , transformation related protein 53 binding-protein 1 , tumor suppressor p53-binding protein 1 , tumor protein 53-binding protein, 1 , tumor protein p53-binding protein, 1 , transformation related protein 53 binding protein 1

415589 Gallus gallus
467668 Pan troglodytes
478274 Canis lupus familiaris
509111 Bos taurus
100137429 Papio anubis
100468474 Ailuropoda melanoleuca
100490124 Xenopus (Silurana) tropicalis
100550605 Meleagris gallopavo
100607698 Nomascus leucogenys
100328680 Oryctolagus cuniculus
27223 Mus musculus
7158 Homo sapiens
296099 Rattus norvegicus
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