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Browse our XRCC4 (XRCC4) ELISA Kits

Full name:
X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 ELISA Kits (XRCC4)
On www.antibodies-online.com are 3 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) ELISA Kits from 3 different suppliers available. Additionally we are shipping XRCC4 Antibodies (104) and XRCC4 Proteins (6) and many more products for this protein. A total of 122 XRCC4 products are currently listed.
Synonyms:
2310057B22Rik, AW413319, AW545101, homolog of human DNA ligase iv-binding protein XRCC4, MGC81443, zgc:73312
list all ELISA KIts Gene Name GeneID UniProt
XRCC4 7518 Q13426
Mouse XRCC4 XRCC4 108138 Q924T3
Rat XRCC4 XRCC4 309995  

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XRCC4 (XRCC4) ELISA Kits by Reactivity

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More ELISA Kits for XRCC4 Interaction Partners

Arabidopsis thaliana X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) interaction partners

  1. XRCC4 has a negative role in Agrobacterium T-DNA integration.

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) interaction partners

  1. Association between insertion/deletion polymorphism in intron 3 of XRCC4 and susceptibility to type I bipolar disorder

  2. For XRCC4 (rs1805377) polymorphism, no difference was found in distribution between the ESCC and control groups.

  3. using dual- and quadruple-trap optical tweezers combined with fluorescence microscopy, we show how human XRCC4, XLF (show NHEJ1 ELISA Kits) and XRCC4-XLF (show NHEJ1 ELISA Kits) complexes interact with DNA in real time

  4. The ends are then closely aligned, which requires XLF (show NHEJ1 ELISA Kits), a non-catalytic function of XRCC4-LIG4 (show LIG4 ELISA Kits), and DNA-PK activity

  5. Polymorphisms of XRCC4 are associated with susceptibility to Colorectal Cancer.

  6. FBXW7 (show FBXW7 ELISA Kits) facilitates nonhomologous end-joining via K63-linked polyubiquitylation of XRCC4 in tumor cells.

  7. The XRCC4 -1394T/G polymorphism is associated with susceptibility to endometriosis in an Iranian population.

  8. Our results suggest that the XRCC4 rs2075685 polymorphism could influence the susceptibility to pancreatic cancer in a Chinese population.

  9. The TMPRSS2 (show TMPRSS2 ELISA Kits)-ERG (show ERG ELISA Kits) Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP (show COL11A2 ELISA Kits) Inhibition

  10. Point mutations in XRCC4 is associated with microcephaly, short stature and genomic instability.

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) interaction partners

  1. Data show that combined deletion of X-ray repair cross-complementing protein 4 (Xrcc4) and tumor suppressor p53 (Trp53 (show TP53 ELISA Kits)) predisposes B cells to lymphomagenesis.

  2. FBXW7 (show FBXW7 ELISA Kits) facilitates nonhomologous end-joining via K63-linked polyubiquitylation of XRCC4 in tumor cells.

  3. The present results collectively indicated that Lys271, but not Lys210, of XRCC4 is required for the nuclear localization of XRCC4 and LIG4 (show LIG4 ELISA Kits) and that the nuclear localizing ability is essential for DSB repair function of XRCC4.

  4. DNA-PK and ATM (show ATM ELISA Kits) acts in parallel upstream of XRCC4, regulating through phosphorylation

  5. XRCC4 C-terminal point mutants, R325F and N326L, are functionally deficient in terms of cell survival after irradiation.

  6. These results establish that nonrecurrent CNVs can be, and frequently are, formed by mechanisms other than Xrcc4-dependent NHEJ.

  7. analysis of the association of radiation-induced XRCC4 with chromatin DNA, by biochemical fractionation

  8. conditional inactivation of the XRCC4 in nestin (show NES ELISA Kits)-expressing neuronal progenitor cells, although leading to no obvious phenotype in a WT background, leads to early onset of neuronally differentiated medulloblastomas (MBs (show NEU2 ELISA Kits)) in a p53 (show TP53 ELISA Kits)-deficient background

  9. DNA-PK kinase activity results in disassembly of the Ku/DNA ligase IV (show LIG4 ELISA Kits)/Xrcc4 complex

  10. Connection of XRCC4 and the nonhomologous end joining DNA repair pathway to immunoglobulin class switch recombination.

XRCC4 Antigen Profile

Antigen Summary

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.

Alternative names and synonyms associated with XRCC4

  • X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4) Elisa Kit
  • X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4) Elisa Kit
  • DNA repair protein XRCC4-like protein (XRCC4) Elisa Kit
  • X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4) Elisa Kit
  • 2310057B22Rik Elisa Kit
  • AW413319 Elisa Kit
  • AW545101 Elisa Kit
  • homolog of human DNA ligase iv-binding protein XRCC4 Elisa Kit
  • MGC81443 Elisa Kit
  • zgc:73312 Elisa Kit

Protein level used designations for XRCC4

DNA repair protein XRCC4 , X-ray repair complementing defective repair in Chinese hamster cells 4 , DNA-repair protein XRCC4 , X-ray repair cross complementing protein 4 , X-ray repair cross-complementing protein 4 , X-ray repair, complementing defective, repair in Chinese hamster

GENE ID SPECIES
488923 Canis lupus familiaris
393759 Danio rerio
427325 Gallus gallus
443786 Xenopus laevis
471491 Pan troglodytes
100127743 Xenopus (Silurana) tropicalis
100173078 Pongo abelii
100603402 Nomascus leucogenys
821885 Arabidopsis thaliana
7518 Homo sapiens
613590 Bos taurus
108138 Mus musculus
309995 Rattus norvegicus
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