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Browse our XRCC5 (XRCC5) ELISA Kits

Full name:
X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) ELISA Kits (XRCC5)
On www.antibodies-online.com are 29 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5) ELISA Kits from 8 different suppliers available. Additionally we are shipping XRCC5 Antibodies (264) and XRCC5 Proteins (3) and many more products for this protein. A total of 311 XRCC5 products are currently listed.
Synonyms:
AI314015, KARP-1, KARP1, KU80, Ku86, KUB2, Kup80, NFIV, XRCC5, xrcc5-a
list all ELISA KIts Gene Name GeneID UniProt
XRCC5 22596 P27641
XRCC5 363247  
XRCC5 7520 P13010

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Show all synonyms

More ELISA Kits for XRCC5 Interaction Partners

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5) interaction partners

  1. Ku (ku70 (show XRCC6 ELISA Kits)/ku80 heterodimer)roles in nonhomologous end joining and base excision repair pathways of DNA repair are overviewed.

  2. the downregulation of Ku80 and an impairment of repair activity in squamous cells, which are mediated by miR (show MLXIP ELISA Kits)-31.

  3. Inactivation of Ku80 and DNA-PKCS (show PRKDC ELISA Kits) causes reduced lifespan and bodyweight.

  4. A novel role for free Ku70 (show XRCC6 ELISA Kits) and free Ku80 in altering base excision repair.

  5. Ku80 plays an important role in base excision repair.

  6. Ku70/80 binds to DNA double strand breaks (DSB) in all cell cycle stages and is likely actively displaced from DSB ends to free the DNA ends for DNA end resection and thus homologous recombination to occur.

  7. There was a dose-dependent and time-dependent increase in Ku80 mRNA levels in nude mice that were inoculated with A549 cells and exposed to varying doses of irradiation.

  8. Ku70 (show XRCC6 ELISA Kits)/86 binds to the Apaf1 (show APAF1 ELISA Kits) promoter and represses its activity.

  9. Mobility of a major portion of Ku80 is not affected by DNA double strans breaks (DSBs) in order to find other DSBs in hamster cells.

  10. It was concluded that Ku86 deficiency accelerates high NaCl induced cellular senescence in cultured cells, C. elegans, and knockout mouse kidney.

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5) interaction partners

  1. DNA methylation (show HELLS ELISA Kits) modification plays an important role to regulate the gene expression of XRCC5 and XRCC7 (show PRKDC ELISA Kits), from the results that the gene methylation level of the glioma group is higher than that of the normal group

  2. Data suggest that heat shock factor 1 (HSF1) interacts with both Ku autoantigens Ku70 and Ku86 to induce defective non-homologous end joining (NHEJ) repair activity and genomic instability.

  3. The present study showed that the XRCC5 locus might be a contributor to COPD susceptibility in the Chinese Han population.

  4. Depletion of Ku80 in the lens through acute change or a consequence of aging is likely to increase levels of DNA strand breaks, which could negatively influence physiological function and promote lens opacity (show MIP ELISA Kits)

  5. Data show that ubiquitin E3 ligase RNF138 (show RNF138 ELISA Kits) regulates Ku80 antigen ubiquitylation in response to DNA damage.

  6. Polymorphisms in the Variable Number of Tandem Repeats at the promoter region of the XRCC5 is associated with gastric cancer.

  7. retinoblastoma tumor suppressor protein (show TP53 ELISA Kits) variants disabled for the interaction with XRCC5 and XRCC6 (show XRCC6 ELISA Kits), including a cancer-associated variant, are unable to support canonical non-homologous end-joining despite being able to confer cell-cycle control

  8. Genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans generated independent evidence for the involvement of XRCC5 (Ku80) in alcohol dependence

  9. Our data indicated that Ku80 expression level associates with key clinicopathological features and is an independent predictor of the OS and the DFS (show FST ELISA Kits) in pT2N0M0 ESCC patients.

  10. Polymorphism in XRCC5 gene is associated with Systemic Lupus Erythematosus.

Xenopus laevis X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5) interaction partners

  1. Double strand break (DSB)-induced ubiquitylation of Ku80 provides a mechanism to efficiently eliminate Ku from DNA for pre- and postrepair processes.

XRCC5 Antigen Profile

Antigen Summary

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Alternative names and synonyms associated with XRCC5

  • X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5) Elisa Kit
  • X-ray repair complementing defective repair in Chinese hamster cells 5 (Xrcc5) Elisa Kit
  • X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (xrcc5) Elisa Kit
  • X-ray repair cross-complementing protein 5-like (LOC531945) Elisa Kit
  • AI314015 Elisa Kit
  • KARP-1 Elisa Kit
  • KARP1 Elisa Kit
  • KU80 Elisa Kit
  • Ku86 Elisa Kit
  • KUB2 Elisa Kit
  • Kup80 Elisa Kit
  • NFIV Elisa Kit
  • XRCC5 Elisa Kit
  • xrcc5-a Elisa Kit

Protein level used designations for XRCC5

Ku autoantigen , X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) , X-ray repair protein , X-ray repair cross-complementing protein 5 , X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) , ATP-dependent DNA helicase II , ATP-dependent DNA helicase 2 subunit 2-like , x-ray repair cross-complementing protein 5-like , ATP-dependent DNA helicase 2 subunit 2 , ATP-dependent DNA helicase II 80 kDa subunit , CTC box-binding factor 85 kDa subunit , CTC85 , CTCBF , DNA repair protein XRCC5 , Ku p80 , ku autoantigen protein p86 homolog , nuclear factor IV , Ku autoantigen, 80kD) , X-ray repair cross complementation (double-strand-break rejoining , X-ray repair cross complementation (double-strand-break rejoining; Ku autoantigen, 80kD) , 86 kDa subunit of Ku antigen , Ku autoantigen, 80kDa , Ku86 autoantigen related protein 1 , TLAA , lupus Ku autoantigen protein p86 , thyroid-lupus autoantigen , X-ray repair complementing defective repair in Chinese hamster cells 5

GENE ID SPECIES
449614 Pan troglodytes
478902 Canis lupus familiaris
574279 Macaca mulatta
100173343 Pongo abelii
100347656 Oryctolagus cuniculus
100409742 Callithrix jacchus
100484832 Ailuropoda melanoleuca
100514133 Sus scrofa
100603811 Nomascus leucogenys
22596 Mus musculus
363247 Rattus norvegicus
7520 Homo sapiens
394397 Xenopus laevis
424222 Gallus gallus
531945 Bos taurus
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