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Browse our anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antibodies

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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Antibodies (XRCC6)
On www.antibodies-online.com are 333 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antibodies from 28 different suppliers available. Additionally we are shipping X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Kits (16) and X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Proteins (10) and many more products for this protein. A total of 380 X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 products are currently listed.
Synonyms:
70kDa, CTC75, CTCBF, G22p1, Ku70, Kup70, ML8, TLAA
list all antibodies Gene Name GeneID UniProt
XRCC6 2547 P12956
XRCC6 14375 P23475
XRCC6 25019  

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Top referenced anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Antibodies

  1. Human Monoclonal XRCC6 Primary Antibody for IF, WB - ABIN396279 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN396279

  2. Human Monoclonal XRCC6 Primary Antibody for WB - ABIN395937 : Liu, Shete, Wang, El-Zein, Etzel, Liang, Armstrong, Tsavachidis, Gilbert, Aldape, Xing, Wu, Wei, Bondy: Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk. in Carcinogenesis 2010 (PubMed)
    Show all 5 references for ABIN395937

  3. Human Polyclonal XRCC6 Primary Antibody for FACS, IF - ABIN651280 : Vishnudas, Miller: Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy. in Human molecular genetics 2009 (PubMed)
    Show all 3 references for ABIN651280

  4. Hamster Monoclonal XRCC6 Primary Antibody for ICC, FACS - ABIN151413 : Doster, Ziegler, Foermer, Rieker, Heeg, Bekeredjian-Ding: Phosphorothioate-modified CpG oligodeoxynucleotides mimic autoantigens and reveal a potential role for Toll-like receptor 9 in receptor revision. in Immunology 2013 (PubMed)
    Show all 2 references for ABIN151413

  5. Human Polyclonal XRCC6 Primary Antibody for WB - ABIN374763 : Ribes-Zamora, Mihalek, Lichtarge, Bertuch: Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions. in Nature structural & molecular biology 2007 (PubMed)

  6. Human Polyclonal XRCC6 Primary Antibody for FACS, IF - ABIN651281 : Sobczuk, Smolarz, Romanowicz, Zadrozny, Baszczyński, Westfal, Pertyński: Analysis of the polymorphisms in non-homologous DNA end joining (NHEJ) gene Ku70 and Ligase IV in sporadic breast cancer in women. in Polish journal of pathology : official journal of the Polish Society of Pathologists 2010 (PubMed)

  7. Dog (Canine) Polyclonal XRCC6 Primary Antibody for IHC, WB - ABIN2778270 : Sawchuk, Mansilla-Soto, Alarcon, Singha, Langen, Bianchi, Lees-Miller, Nussenzweig, Cortes: Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 Interaction Partners

Human X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) interaction partners

  1. Data show that the increased acetylation of Ku autoantigen 70kDa (Ku70) in sirtuin 6 (show SIRT6 Antibodies) protein (SIRT6 (show SIRT6 Antibodies))-depleted cells disrupt its interaction with Bax (show BAX Antibodies) apoptosis regulator protein (Bax (show BAX Antibodies)), which finally resulted in Bax (show BAX Antibodies) mitochondrial translocalization.

  2. Ku70 (XRCC6) was found to bind directly within the CR4 of E1A (show BCKDHA Antibodies) from human adenovirus type 5.

  3. periodic phosphorylation of Ku70 by cyclin-cyclin (show PCNA Antibodies) dependent kinases prevents the interaction of Ku with replication origin after initiation events in S-phase.

  4. The results of this preclinical study imply that Ku70 might be a primary resistance factor of gemcitabine, and Ku70 silence could significantly chemo-sensitize gemcitabine in pancreatic cancer cells.

  5. results reveal that Src (show SRC Antibodies) plays a protective role against hyperactive apoptotic cell death by reducing apoptotic susceptibility through phosphorylation of Ku70 at Tyr (show TYR Antibodies)-530.

  6. High Expression of XRCC6 Promotes Human Osteosarcoma Cell Proliferation through the beta-Catenin (show CTNNB1 Antibodies)/Wnt (show WNT2 Antibodies) Signaling Pathway.

  7. Data show that X-ray repair cross-complementing protein 6 ( Ku70) is found to interact with closed circular DNA.

  8. The rs2267437 in XRCC6 was associated with increased initial DSB damage.

  9. Ku70 expression may play an important role in hepatocellular carcinoma development

  10. Results show that under hypoxia, Ku70 and DNA-PKcs (show PRKDC Antibodies) interact with nuclear RON (show MST1R Antibodies) which activates non-homologous end joining DNA repair conferring chemoresistance.

Mouse (Murine) X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) interaction partners

  1. Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice.

  2. Bax deficiency appeared to delay the development of emphysema. This study suggests that enhanced Bax activity exacerbates the negative impact of Ku70 deletion

  3. Ku (ku70/ku80 (show XRCC5 Antibodies) heterodimer)roles in nonhomologous end joining and base excision repair pathways of DNA repair are overviewed.

  4. A novel role for free Ku70 and free Ku80 (show XRCC5 Antibodies) in altering base excision repair.

  5. A novel function of Ku70 essential for colon homeostasis.

  6. Overexpression of Bcl2 rescues the hematopoietic stem cell defect in Ku70-deficient mice by restoration of quiescence.

  7. This study highlights Ku70 as an important player not only in maintaining genomic stability through NHEJ-dependent functions, but also in regulating pancreatic beta-cell proliferation, a novel NHEJ-independent function.

  8. Ku70/80 binds to DNA double strand breaks (DSB) in all cell cycle stages and is likely actively displaced from DSB ends to free the DNA ends for DNA end resection and thus homologous recombination to occur.

  9. The findings suggest that Artemis (show DCLRE1C Antibodies) can work in not only the Ku-dependent repair process, but also the Ku-independent process at DNA double-strand break in living epithelial cells.

  10. These findings clearly indicate that Ku70 plays a key role in regulation of the Ku80 (show XRCC5 Antibodies) expression level in and the radioresistance of lung epithelial cells.

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antigen Profile

Antigen Summary

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Alternative names and synonyms associated with X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6)

  • X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6) antibody
  • ATP-dependent DNA helicase II, 70 kDa subunit (Bm1_41430) antibody
  • ATP-dependent DNA helicase II, 70 kDa subunit (LOC100351956) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 6 (xrcc6) antibody
  • X-ray repair complementing defective repair in Chinese hamster cells 6 (Xrcc6) antibody
  • 70kDa antibody
  • CTC75 antibody
  • CTCBF antibody
  • G22p1 antibody
  • Ku70 antibody
  • Kup70 antibody
  • ML8 antibody
  • TLAA antibody

Protein level used designations for XRCC6

ATP-dependent DNA helicase 2 subunit 1 , ATP-dependent DNA helicase II, 70 kDa subunit , X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) , X-ray repair cross-complementing protein 6 , 5'-dRP lyase Ku70 , 5'-deoxyribose-5-phosphate lyase Ku70 , 70 kDa subunit of Ku antigen , ATP-dependent DNA helicase II 70 kDa subunit , CTC box binding factor 75 kDa subunit , CTC box-binding factor 75 kDa subunit , DNA repair protein XRCC6 , Ku autoantigen p70 subunit , Ku autoantigen, 70kDa , lupus Ku autoantigen protein p70 , thyroid autoantigen 70kD (Ku antigen) , thyroid autoantigen 70kDa (Ku antigen) , thyroid-lupus autoantigen p70 , 5'-dRP/AP lyase Ku70 , CTC75 , CTCBF , Ku p70 , ku autoantigen protein p70 homolog , thyroid autoantigen 70 kDa , Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa) , thyroid autoantigen , X-ray repair cross-complementing protein 5

GENE ID SPECIES
465902 Pan troglodytes
6103167 Brugia malayi
100351956 Oryctolagus cuniculus
398357 Xenopus laevis
474485 Canis lupus familiaris
510132 Bos taurus
707975 Macaca mulatta
100173902 Pongo abelii
2547 Homo sapiens
14375 Mus musculus
25019 Rattus norvegicus
395767 Gallus gallus
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