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anti-Human GINS1 Antibodies:
anti-Mouse (Murine) GINS1 Antibodies:
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Human Polyclonal GINS1 Primary Antibody for EIA, WB - ABIN952518
Kang, Galal, Farina, Tappin, Hurwitz: Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis. in Proceedings of the National Academy of Sciences of the United States of America 2012
Show all 4 references for ABIN952518
Human Polyclonal GINS1 Primary Antibody for WB - ABIN653447
Nagahama, Ueno, Miyamoto, Morii, Minami, Mochizuki, Saya, Takakura: PSF1, a DNA replication factor expressed widely in stem and progenitor cells, drives tumorigenic and metastatic properties. in Cancer research 2010
Show all 3 references for ABIN653447
Cow (Bovine) Polyclonal GINS1 Primary Antibody for WB - ABIN2782573
Ueno, Itoh, Kong, Sugihara, Asano, Takakura: PSF1 is essential for early embryogenesis in mice. in Molecular and cellular biology 2005
Data show the structure of the Cdc45 (show CDC45 Antibodies)/Mcm2-7 (show MCM2 Antibodies)/Psf1 GINS (CMG (show CASK Antibodies)) helicase (show DNA2 Antibodies) in the presence of ATPgammaS and a DNA duplex bearing a 3' single-stranded tail.
CDC-48/p97 (show vcp Antibodies) coordinates CDT-1 (show CDT1 Antibodies) degradation with GINS chromatin dissociation to ensure faithful DNA replication
PSF1 (show TAP1 Antibodies) mRNA expression was an independent factor associated with prognosis of colorectal cancer.
These results suggest that PSF1 (show TAP1 Antibodies) over-expression is specifically involved in breast cancer cell growth.
Findings implicate PSF1 (show TAP1 Antibodies) in tumorigenesis and offer initial evidence of its potential as a theranostic target.
expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha (show ESR1 Antibodies), and PSF3 (show GINS3 Antibodies) acts as a gene responsive to transcription factor E2F1 (show E2F1 Antibodies)
the C-terminal domain of Psf1 (show TAP1 Antibodies) does not contribute to the stability of the GINS complex but is crucial for chromatin binding and replication activity
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4\; MIM 610611), Psf1, Psf2 (GINS2\; MIM 610609), and Psf3 (GINS3\; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005
DNA replication complex GINS protein PSF1
, DNA replication complex GINS protein psf1
, GINS complex subunit 1
, GINS complex subunit 1 (Psf1 homolog)
, partner of sld five-1
, GINS complex subunit 4 (Sld5 homolog)
, potential GINS DNA replication initiation complex subunit